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TXNDC11 Antibody – Goat Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS422889

MBS422889 is an antibody targeting TXNDC11. Also known as Goat anti-TXNDC11 (aa113-126) Antibody. Reactive in Tested: Human; Expected from sequence similarity: Human. Host: Goat. More details

$450 / 0.1 mg +1 FREE 8GB USB
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
TXNDC11, Polyclonal Antibody
Full Product Name
Goat anti-TXNDC11 (aa113-126) Antibody
Product Gene Name
Product Synonym Names
TXNDC11; thioredoxin domain containing 11; EFP1; EF-hand binding protein 1; EF-hand-binding protein 1; thioredoxin domain-containing protein 11; TXNDC11 antibody; thioredoxin domain containing 11 antibody; EFP1 antibody; EF-hand binding protein 1 antibody; EF-hand-binding protein 1 antibody; thioredoxin domain-containing protein 11 antibody; TXNDC11 (aa113-126)
Immunogen Sequence
QLDYAEYVRR DSE
Clonality
Polyclonal
Host
Goat
Species Reactivity
Tested: Human; Expected from sequence similarity: Human
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration
100ug specific antibody in 200ul (lot specific)
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.
Antibody/Peptide Pairs
TXNDC11 peptide (MBS427703) is used for blocking the activity of TXNDC11 antibody (MBS422889)
Molecular Weight
30,375 Da
Immunogen
Peptide with sequence C-QLDYAEYVRRDSE, from the internal region of the protein sequence according to NP_056998.4.
Epitope
Internal region
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Applications Tested/Suitable for anti-TXNDC11 antibody
Peptide ELISA (EIA), Western Blot (WB)
Application Notes for anti-TXNDC11 antibody
Peptide ELISA: Antibody detection limit dilution 1: 16000.
Western Blot: Approx 100kDa band observed in Human Spleen and Thymus lysates (calculated MW of 108kDa according to NP_056998.4). Recommended concentration: 1-3ug/ml.

Western Blot (WB) of anti-TXNDC11 antibody

(1ug/ml) staining of Human Thymus lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Goat Anti-TXNDC11 Polyclonal Antibody – Cat# MBS422889

Other Notes

Small volumes of anti-TXNDC11 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TXNDC11. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
thioredoxin domain-containing protein 11 isoform 2
NCBI Official Synonym Full Names
thioredoxin domain containing 11
NCBI Official Symbol
TXNDC11
NCBI Official Synonym Symbols
EFP1
UniProt Protein Name
Thioredoxin domain-containing protein 11
UniProt Synonym Protein Names
EF-hand-binding protein 1
UniProt Gene Name
TXNDC11
UniProt Synonym Gene Names
EFP1
UniProt Entry Name
TXD11_HUMAN
NCBI Protein Information
thioredoxin domain-containing protein 11

UniProt Comments for TXNDC11

TXNDC11: May act as a redox regulator involved in DUOX proteins folding. The interaction with DUOX1 and DUOX2 suggest that it belongs to a multiprotein complex constituting the thyroid H(2)O(2) generating system. It is however not sufficient to assist DUOX1 and DUOX2 in H(2)O(2) generation. Belongs to the protein disulfide isomerase family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 16p13.13

Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane

Molecular Function: protein binding; protein disulfide isomerase activity

Biological Process: cell redox homeostasis; protein folding
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-TXNDC11 antibody

 Reference Product  PubMed Publications
 DUOX1 antibody  >1 publications with TXNDC11 and DUOX1

Organs/Tissues associated with anti-TXNDC11 antibody

 Organ/Tissue Name  Pubmed Publications
 Thyroid Antibodies  >1 publications with TXNDC11 and Thyroid
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