Rabbit Anti-USP2 Polyclonal Antibody – Cat# MBS6008653

UBP46 Antibody (C-term) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the UBP46 antibody detected the UBP46 protein (arrow).

UBP46 (USP2) Antibody – Rabbit Polyclonal

Name: USP2 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6008653
Price: 895 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6008653

Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes. USP46 belongs to a large family of cysteine proteases that function as… More details

$895 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

UBP46 (USP2), Polyclonal Antibody

Full Product Name

UBP46, CT (USP46, Ubiquitin carboxyl-terminal hydrolase 46, Deubiquitinating enzyme 46, Ubiquitin thioesterase 46, Ubiquitin-specific-processing protease 46)

Product Gene Name

anti-USP2 antibody

Product Synonym Names

Anti -UBP46, CT (USP46, Ubiquitin carboxyl-terminal hydrolase 46, Deubiquitinating enzyme 46, Ubiquitin thioesterase 46, Ubiquitin-specific-processing protease 46)

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Purity/Purification

Affinity Purified
Purified by Protein A affinity chromatography.

Specificity

Human

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

40,932 Da

Chromosome Location

Chromosome: 24; NC_006111.3 (4179526..4184536). Location: chromosome: 24

3D Structure

ModBase 3D Structure for O57429

Immunogen

UBP46 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 240-269 amino acids from the C-terminal region of human UBP46.

Product Categories/Family for anti-USP2 antibody

Antibodies; Abs to Ubiquitin

Applications Tested/Suitable for anti-USP2 antibody

ELISA (EL/EIA), Western Blot (WB)

Application Notes for anti-USP2 antibody

Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500

Other Notes

Small volumes of anti-USP2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for USP2 purchase

MBS6008653 is an antibody targeting USP2. Also known as UBP46, CT (USP46, Ubiquitin carboxyl-terminal hydrolase 46, Deubiquitinating enzyme 46, Ubiquitin thioesterase 46, Ubiquitin-specific-processing protease 46). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for USP2. It may not necessarily be applicable to this product.

NCBI GI #

45382531

NCBI GeneID

395766

NCBI Accession #

NP_990257.1

UniProt Primary Accession #

O57429

UniProt Related Accession #

O57429

GenBank Nucleotide #

NM_204926.1

NCBI Official Full Name

ubiquitin carboxyl-terminal hydrolase 2

NCBI Official Synonym Full Names

ubiquitin specific peptidase 2

NCBI Official Symbol

USP2

NCBI Official Synonym Symbols

UBP41; UBP46; ubp52; ubp66

UniProt Protein Name

Ubiquitin carboxyl-terminal hydrolase 2

UniProt Synonym Protein Names

41 kDa ubiquitin-specific protease; Deubiquitinating enzyme 2; Ubiquitin thioesterase 2; Ubiquitin-specific-processing protease 2

Protein Family

Protein

UniProt Gene Name

USP2

UniProt Synonym Gene Names

UBP41

UniProt Entry Name

UBP2_CHICK

NCBI Protein Information

ubiquitin carboxyl-terminal hydrolase 2; ubiquitin thioesterase 2; deubiquitinating enzyme 2; ubiquitin thiolesterase 2; family of cysteine protease; ubiquitin specific protease 2; ubiquitin specific protease 41; ubiquitin specific protease 46; ubiquitin specific protease 52; ubiquitin specific protease 66; 41 kDa ubiquitin-specific protease; ubiquitin-specific-processing protease 2

UniProt Comments for USP2

Function: Hydrolase that deubiquitinates polyubiquitinated target proteins such as MDM2, MDM4 and CCND1. Possesses both ubiquitin-specific peptidase and isopeptidase activities

By similarity.

Catalytic activity: Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).

Cofactor: Binds 1 zinc ion

By similarity.

Subunit structure: Homooligomer

By similarity.

Subcellular location: Cytoplasm

By similarity. Cytoplasm › perinuclear region

By similarity.

Sequence similarities: Belongs to the peptidase C19 family. USP2 subfamily.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-USP2 antibody

Reference Product	PubMed Publications
USP5 antibody	>3 publications with USP2 and USP5
GREM2 antibody	>1 publications with USP2 and GREM2
CBL antibody	>1 publications with USP2 and CBL

Organs/Tissues associated with anti-USP2 antibody

Organ/Tissue Name	Pubmed Publications
Liver Antibodies	>11 publications with USP2 and Liver
Muscle Antibodies	>11 publications with USP2 and Muscle
Testis Antibodies	>6 publications with USP2 and Testis
Brain Antibodies	>4 publications with USP2 and Brain
Embryonic Tissue Antibodies	>3 publications with USP2 and Embryonic Tissue