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UQCRC1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6361698

This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1. More details

$1060 / 0.2 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
UQCRC1, Polyclonal Antibody
Full Product Name
UQCRC1, NT (UQCRC1, Cytochrome b-c1 complex subunit 1, mitochondrial, Complex III subunit 1, Core protein I, Ubiquinol-cytochrome-c reductase complex core protein 1) (Biotin)
Product Gene Name
anti-UQCRC1 antibody
Product Synonym Names
UQCRC1; Cytochrome b-c1 complex subunit 1, mitochondrial; Complex III subunit 1; Core protein I; Ubiquinol-cytochrome-c reductase complex core protein 1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
52,646 Da
OMIM
191328
3D Structure
ModBase 3D Structure for P31930
Immunogen
UQCRC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 141-170 amino acids from the N-terminal region of human UQCRC1.
Conjugate
Biotin
Note
Preservative Free

Product Categories/Family for anti-UQCRC1 antibody

Antibodies; Enzymes; Cytochrome
Applications Tested/Suitable for anti-UQCRC1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-UQCRC1 antibody
WB: 1:100-500
ELISA: 1:1,000
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-UQCRC1 antibody

UQCRC1 Antibody (N-term) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the UQCRC1 antibody detected the UQCRC1 protein (arrow).
Rabbit Anti-UQCRC1 Polyclonal Antibody – Cat# MBS6361698

Product References and Citations for anti-UQCRC1 antibody

Martins-de-Souza, D., et al. J Psychiatr Res 43(11):978-986(2009). Martins-de-Souza, D., et al. Eur Arch Psychiatry Clin Neurosci 259(3):151-163(2009). Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007): Kulawiec, M., et al. Cancer Biol. Ther. 5(8):967-975(2006). Aboulaich, N., et al. Biochem. J. 383 (PT 2), 237-248 (2004).

Other Notes

Small volumes of anti-UQCRC1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for UQCRC1 purchase

MBS6361698 is an antibody targeting UQCRC1. Also known as UQCRC1, NT (UQCRC1, Cytochrome b-c1 complex subunit 1, mitochondrial, Complex III subunit 1, Core protein I, Ubiquinol-cytochrome-c reductase complex core protein 1) (Biotin). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for UQCRC1. It may not necessarily be applicable to this product.

NCBI GI #
46593007
NCBI GeneID
7384
NCBI Accession #
NP_003356.2
UniProt Primary Accession #
P31930
UniProt Secondary Accession #
Q96DD2; B2R7R8
UniProt Related Accession #
P31930
GenBank Nucleotide #
NM_003365.2
NCBI Official Full Name
cytochrome b-c1 complex subunit 1, mitochondrial
NCBI Official Synonym Full Names
ubiquinol-cytochrome c reductase core protein I
NCBI Official Symbol
UQCRC1
NCBI Official Synonym Symbols
QCR1; UQCR1; D3S3191
UniProt Protein Name
Cytochrome b-c1 complex subunit 1, mitochondrial
UniProt Synonym Protein Names
Complex III subunit 1; Core protein I; Ubiquinol-cytochrome-c reductase complex core protein 1
UniProt Gene Name
UQCRC1
UniProt Entry Name
QCR1_HUMAN
NCBI Protein Information
cytochrome b-c1 complex subunit 1, mitochondrial; complex III subunit 1; core protein I; ubiquinol-cytochrome-c reductase complex core protein 1

UniProt Comments for UQCRC1

UQCRC1: This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1. Belongs to the peptidase M16 family. UQCRC1/QCR1 subfamily.

Protein type: EC 1.10.2.2; Mitochondrial; Energy Metabolism - oxidative phosphorylation; Oxidoreductase

Chromosomal Location of Human Ortholog: 3p21.3

Cellular Component: mitochondrion; mitochondrial inner membrane; mitochondrial respiratory chain complex III; mitochondrial respiratory chain

Molecular Function: metal ion binding; ubiquinol-cytochrome-c reductase activity; protein complex binding

Biological Process: response to alkaloid; cellular metabolic process; aerobic respiration; response to activity; oxidative phosphorylation; mitochondrial electron transport, ubiquinol to cytochrome c
Show more

Research Articles on UQCRC1

1. Observational study of gene-disease association. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-UQCRC1 antibody

 Reference Product  PubMed Publications
 UQCRC2 antibody  >4 publications with UQCRC1 and UQCRC2
 NDUFS3 antibody  >1 publications with UQCRC1 and NDUFS3
 COX5A antibody  >1 publications with UQCRC1 and COX5A
 NDUFV1 antibody  >1 publications with UQCRC1 and NDUFV1
 CYC1 antibody  >1 publications with UQCRC1 and CYC1
 UQCRQ antibody  >1 publications with UQCRC1 and UQCRQ

Pathways associated with anti-UQCRC1 antibody

 Products by Pathway  Pathway Diagram
 Alzheimer's Disease Pathway antibodies  Alzheimer's Disease Pathway Diagram
 Alzheimer's Disease Pathway antibodies  Alzheimer's Disease Pathway Diagram
 Cardiac Muscle Contraction Pathway antibodies  Cardiac Muscle Contraction Pathway Diagram
 Cardiac Muscle Contraction Pathway antibodies  Cardiac Muscle Contraction Pathway Diagram
 Cytochrome Bc1 Complex Pathway antibodies  Cytochrome Bc1 Complex Pathway Diagram
 Cytochrome Bc1 Complex Pathway antibodies  Cytochrome Bc1 Complex Pathway Diagram
 Electron Transport Chain Pathway antibodies  Electron Transport Chain Pathway Diagram
 Huntington's Disease Pathway antibodies  Huntington's Disease Pathway Diagram
 Huntington's Disease Pathway antibodies  Huntington's Disease Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram

Diseases associated with anti-UQCRC1 antibody

 Disease Name  Pubmed Publications
 Insulin Resistance Antibodies  >4 publications with UQCRC1 and Insulin Resistance
 Cardiovascular Diseases Antibodies  >2 publications with UQCRC1 and Cardiovascular Diseases
 Nervous System Diseases Antibodies  >2 publications with UQCRC1 and Nervous System Diseases
 Weight Gain Antibodies  >1 publications with UQCRC1 and Weight Gain
 Vascular Diseases Antibodies  >1 publications with UQCRC1 and Vascular Diseases
 Hypertrophy Antibodies  >1 publications with UQCRC1 and Hypertrophy
 Diabetes Mellitus Antibodies  >1 publications with UQCRC1 and Diabetes Mellitus
 Heart Diseases Antibodies  >1 publications with UQCRC1 and Heart Diseases
 Inflammation Antibodies  >1 publications with UQCRC1 and Inflammation
 Cardiovascular Abnormalities Antibodies  >1 publications with UQCRC1 and Cardiovascular Abnormalities

Organs/Tissues associated with anti-UQCRC1 antibody

 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >10 publications with UQCRC1 and Muscle
 Brain Antibodies  >4 publications with UQCRC1 and Brain
 Vascular Antibodies  >2 publications with UQCRC1 and Vascular
 Heart Antibodies  >2 publications with UQCRC1 and Heart
 Liver Antibodies  >2 publications with UQCRC1 and Liver
 Ovary Antibodies  >2 publications with UQCRC1 and Ovary
 Bone Antibodies  >1 publications with UQCRC1 and Bone
 Blood Antibodies  >1 publications with UQCRC1 and Blood
 Uterus Antibodies  >1 publications with UQCRC1 and Uterus
 Nerve Antibodies  >1 publications with UQCRC1 and Nerve
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