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VIM Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9406642

This gene encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the… More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
VIM, Polyclonal Antibody
Full Product Name
VIM Antibody
Product Gene Name
anti-VIM antibody
Product Synonym Names
Vimentin
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied at 0.7mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.3, 0.05% sodium azide and 50% glycerol.
Specificity
The antibody detects endogenous level of total VIM protein.
Preparation and Storage
Store at -20 degree C/1 year
Molecular Weight
53,652 Da
OMIM
116300
Immunogen Type
Recombinant protein
Immunogen Description
Fusion protein corresponding to a region derived from 96-407 amino acids of Human Vimentin
Target Name
VIM

Product Categories/Family for anti-VIM antibody

Total protein Ab
Applications Tested/Suitable for anti-VIM antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-VIM antibody
ELISA: 1:1000-1:5000
Western blotting: 1:200-1:1000

Testing Data of anti-VIM antibody

Gel: 8%SDS-PAGELane1: Hela cell lysateLane2: 293T cell lysateLysates: 30ug per lanePrimary antibody: 1/250 dilutionSecondary antibody: Donkey anti Rabbit IgG - H&L (HRP) at 1/3000 dilutionExposure time: 30 seconds
Rabbit Anti-VIM Polyclonal Antibody – Cat# MBS9406642

Other Notes

Small volumes of anti-VIM antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for VIM purchase

MBS9406642 is an antibody targeting VIM. Also known as VIM Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for VIM. It may not necessarily be applicable to this product.

NCBI GI #
13111800
NCBI GeneID
7431
NCBI Accession #
BC000163
UniProt Secondary Accession #
Q15867; Q15868; Q15869; Q548L2; Q6LER9; Q8N850; Q96ML2; Q9NTM3; B0YJC2; D3DRU4
UniProt Related Accession #
P08670
NCBI Official Full Name
Homo sapiens vimentin, mRNA
NCBI Official Synonym Full Names
vimentin
NCBI Official Symbol
VIM
NCBI Official Synonym Symbols
HEL113; CTRCT30
UniProt Protein Name
Vimentin
Protein Family
Vimentin
UniProt Gene Name
VIM
UniProt Entry Name
VIME_HUMAN
NCBI Protein Information
vimentin

UniProt Comments for VIM

Vimentin: an intermediate filament protein. Intermediate filament proteins are expressed in a tissue-specific manner. Desmin is the subunit specific for muscle and vimentin the subunit specific for mesenchymal tissue.

Protein type: Motility/polarity/chemotaxis; Cytoskeletal

Chromosomal Location of Human Ortholog: 10p13

Cellular Component: cytoplasm; cytoskeleton; cytosol; focal adhesion; intermediate filament; intermediate filament cytoskeleton; leading edge; neuron projection; peroxisome; plasma membrane

Molecular Function: double-stranded RNA binding; glycoprotein binding; identical protein binding; protein binding; protein C-terminus binding; structural constituent of cytoskeleton; structural constituent of eye lens

Biological Process: apoptosis; astrocyte development; Bergmann glial cell differentiation; cell motility; cell structure disassembly during apoptosis; intermediate filament organization; muscle filament sliding; programmed cell death; viral reproduction

Disease: Cataract 30
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Research Articles on VIM

1. This study focused on analyzing the immunoexpression of CK19, vimentin and E-cadherin in a number of 43 differentiated thyroid carcinomas.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-VIM antibody

 Reference Product  PubMed Publications
 CASP3 antibody  >6 publications with VIM and CASP3
 AKT1 antibody  >4 publications with VIM and AKT1
 TPM3 antibody  >1 publications with VIM and TPM3
 CASP8 antibody  >1 publications with VIM and CASP8

Pathways associated with anti-VIM antibody

 Products by Pathway  Pathway Diagram
 Alpha6-Beta4 Integrin Signaling Pathway antibodies  Alpha6-Beta4 Integrin Signaling Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Apoptotic Cleavage Of Cellular Proteins Pathway antibodies  Apoptotic Cleavage Of Cellular Proteins Pathway Diagram
 Apoptotic Execution Phase Pathway antibodies  Apoptotic Execution Phase Pathway Diagram
 Aurora B Signaling Pathway antibodies  Aurora B Signaling Pathway Diagram
 Caspase Cascade In Apoptosis Pathway antibodies  Caspase Cascade In Apoptosis Pathway Diagram
 Caspase-mediated Cleavage Of Cytoskeletal Proteins Pathway antibodies  Caspase-mediated Cleavage Of Cytoskeletal Proteins Pathway Diagram
 Epstein-Barr Virus Infection Pathway antibodies  Epstein-Barr Virus Infection Pathway Diagram
 Epstein-Barr Virus Infection Pathway antibodies  Epstein-Barr Virus Infection Pathway Diagram
 MicroRNAs In Cancer Pathway antibodies  MicroRNAs In Cancer Pathway Diagram

Diseases associated with anti-VIM antibody

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >434 publications with VIM and Nervous System Diseases
 Neurodegenerative Diseases Antibodies  >181 publications with VIM and Neurodegenerative Diseases
 Inflammation Antibodies  >62 publications with VIM and Inflammation
 Kidney Diseases Antibodies  >42 publications with VIM and Kidney Diseases
 Disease Models, Animal Antibodies  >42 publications with VIM and Disease Models, Animal
 Neoplasm Metastasis Antibodies  >38 publications with VIM and Neoplasm Metastasis
 Liver Diseases Antibodies  >37 publications with VIM and Liver Diseases
 Hemorrhage Antibodies  >36 publications with VIM and Hemorrhage
 Breast Neoplasms Antibodies  >35 publications with VIM and Breast Neoplasms
 Fibrosis Antibodies  >34 publications with VIM and Fibrosis

Organs/Tissues associated with anti-VIM antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >521 publications with VIM and Brain
 Blood Antibodies  >229 publications with VIM and Blood
 Muscle Antibodies  >125 publications with VIM and Muscle
 Nerve Antibodies  >86 publications with VIM and Nerve
 Bone Antibodies  >84 publications with VIM and Bone
 Kidney Antibodies  >66 publications with VIM and Kidney
 Liver Antibodies  >62 publications with VIM and Liver
 Bone Marrow Antibodies  >53 publications with VIM and Bone Marrow
 Eye Antibodies  >49 publications with VIM and Eye
 Lung Antibodies  >46 publications with VIM and Lung
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