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VPR Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS7151028

MBS7151028 is an antibody targeting VPR. Also known as Rabbit anti-Human immunodeficiency virus type 1 group M subtype K (isolate 97ZR-EQTB11)(HIV-1) VPR Polyclonal Antibody. Reactive in Human immunodeficiency virus type 1 group M subtype K (isolate… More details

Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
VPR, Polyclonal Antibody
Full Product Name
Rabbit anti-Human immunodeficiency virus type 1 group M subtype K (isolate 97ZR-EQTB11)(HIV-1) VPR Polyclonal Antibody
Product Gene Name
Product Synonym Names
VPR Antibody; Protein Vpr; R ORF protein; Viral protein R; vpr
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human immunodeficiency virus type 1 group M subtype K (isolate 97ZR-EQTB11)(HIV-1)
Form/Format
Liquid
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH7.4
Purity/Purification
Antigen-affinity
Preparation and Storage
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.
Molecular Weight
11,383 Da
3D Structure
ModBase 3D Structure for P0C1P3
Immunogen
Recombinant Human immunodeficiency virus type 1 group M subtype K (isolate 97ZR-EQTB11) (HIV-1) vpr protein
Conjugation
Non-conjugate
Modification
Unmodified
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-VPR antibody
ELISA (EIA), WB (Western Blot) (ensure identification of antigen)

Other Notes

Small volumes of anti-VPR antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for VPR. It may not necessarily be applicable to this product.

NCBI GI #
NCBI Accession #
UniProt Primary Accession #
NCBI Official Full Name
Protein Vpr
UniProt Protein Name
Protein Vpr
UniProt Synonym Protein Names
R ORF protein
UniProt Gene Name
vpr

UniProt Comments for VPR

During virus replication, may deplete host UNG protein, and incude G2-M cell cycle arrest. Acts by targeting specific host proteins for degradation by the 26S proteasome, through association with the cellular CUL4A-DDB1 E3 ligase complex by direct interaction with host VPRPB/DCAF-1. Cell cycle arrest reportedly occurs within hours of infection and is not blocked by antiviral agents, suggesting that it is initiated by the VPR carried into the virion. Additionally, VPR induces apoptosis in a cell cycle dependent manner suggesting that these two effects are mechanistically linked. Detected in the serum and cerebrospinal fluid of AIDS patient, VPR may also induce cell death to bystander cells.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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