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WDR35 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS643201

May promote CASP3 activation and TNF-stimulated apoptosis. Required for ciliogenesis. More details

$915 / 0.05 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
WDR35, Polyclonal Antibody
Full Product Name
WDR35, NT (WD Repeat-containing Protein 35, Intraflagellar Transport Protein 121 Homolog, IFT121, KIAA1336)
Product Gene Name
Product Synonym Names
Anti -WDR35, NT (WD Repeat-containing Protein 35, Intraflagellar Transport Protein 121 Homolog, IFT121, KIAA1336)
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, 0.02% sodium azide.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Specificity
Recognizes human WDR35.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
133,547 Da
Chromosome Location
Chromosome: 2; NC_000002.11 (20110024..20189884, complement). Location: 2p24.1
OMIM
613602
3D Structure
ModBase 3D Structure for Q9P2L0
Immunogen
Synthetic peptide corresponding to the N-terminus of human WDR35.
Applications Tested/Suitable for anti-WDR35 antibody
Immunohistochemistry (IHC)
Application Notes for anti-WDR35 antibody
Suitable for use in Immunohistochemistry.
Dilution: Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml

Immunohistochemistry (IHC) of anti-WDR35 antibody

Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)
Rabbit Anti-WDR35 Polyclonal Antibody – Cat# MBS643201

Immunohistochemistry (IHC) of anti-WDR35 antibody

Human Thyroid: Formalin-Fixed, Paraffin-Embedded (FFPE)
Rabbit Anti-WDR35 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS643201

Other Notes

Small volumes of anti-WDR35 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for WDR35 purchase

MBS643201 is an antibody targeting WDR35. Also known as WDR35, NT (WD Repeat-containing Protein 35, Intraflagellar Transport Protein 121 Homolog, IFT121, KIAA1336). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for WDR35. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
WD repeat-containing protein 35 isoform 2
NCBI Official Synonym Full Names
WD repeat domain 35
NCBI Official Symbol
WDR35
NCBI Official Synonym Symbols
CED2; IFT121
UniProt Protein Name
WD repeat-containing protein 35
UniProt Synonym Protein Names
Intraflagellar transport protein 121 homolog
UniProt Gene Name
WDR35
UniProt Synonym Gene Names
IFT121; KIAA1336
UniProt Entry Name
WDR35_HUMAN
NCBI Protein Information
WD repeat-containing protein 35; naofen; intraflagellar transport protein 121 homolog

NCBI Summary for WDR35

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. Two patients with Sensenbrenner syndrome / cranioectodermal dysplasia (CED) were identified with mutations in this gene, consistent with a possible ciliary function.[provided by RefSeq, Sep 2010]
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UniProt Comments for WDR35

WDR35: a WD40 repeat protein. WD40 repeats are found in a number of eukaryotic proteins that coordinate multi-protein complex assemblies. WD40 proteins are implicated in many functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly. Two alternatively spliced human isoforms have been described.

Protein type: Cytoskeletal

Chromosomal Location of Human Ortholog: 2p24.1

Cellular Component: centrosome; axoneme

Biological Process: organelle organization and biogenesis; cilium biogenesis

Disease: Cranioectodermal Dysplasia 2; Short-rib Thoracic Dysplasia 7 With Or Without Polydactyly
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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