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WNT2B Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9412469

This gene encodes a member of the wingless-type MMTV integration site (WNT) family of highly conserved, secreted signaling factors. WNT family members function in a variety of developmental processes including regulation of cell growth and differentiation and… More details

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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
WNT2B, Polyclonal Antibody
Full Product Name
WNT2B Antibody
Product Gene Name
anti-WNT2B antibody
Product Synonym Names
WNT13
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human
Form/Format
Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Purity/Purification
Antigen affinity purification.
Concentration
0.8 mg/ml (lot specific)
Specificity
The antibody detects endogenous levels of total WNT2B protein.
Preparation and Storage
Store at -20 degree C
Molecular Weight
41,830 Da
OMIM
601968
3D Structure
ModBase 3D Structure for Q93097
Immunogen Type
Peptide
Immunogen Description
Synthetic peptide of human wingless-type MMTV integration site family, member 2B
Target Name
WNT2B

Product Categories/Family for anti-WNT2B antibody

Total protein Ab
Applications Tested/Suitable for anti-WNT2B antibody
Immunohistochemistry (IHC)
Application Notes for anti-WNT2B antibody
Immunohistochemistry: 1:10-1:50

Immunohistochemistry (IHC) of anti-WNT2B antibody

Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using at dilution 1/20.
Rabbit Anti-WNT2B Polyclonal Antibody – Cat# MBS9412469

Other Notes

Small volumes of anti-WNT2B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for WNT2B purchase

MBS9412469 is an antibody targeting WNT2B. Also known as WNT2B Antibody. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for WNT2B. It may not necessarily be applicable to this product.

NCBI GI #
630044901
NCBI GeneID
7482
NCBI Accession #
NP_001278809.1
UniProt Primary Accession #
Q93097
UniProt Secondary Accession #
O14903; Q5TEH9; Q5TEI2; Q9HDC1; Q9HDC2
UniProt Related Accession #
Q93097
GenBank Nucleotide #
NM_001291880.1
NCBI Official Full Name
protein Wnt-2b isoform 3
NCBI Official Synonym Full Names
wingless-type MMTV integration site family, member 2B
NCBI Official Symbol
WNT2B
NCBI Official Synonym Symbols
WNT13
UniProt Protein Name
Protein Wnt-2b
UniProt Synonym Protein Names
Protein Wnt-13
Protein Family
Protein
UniProt Gene Name
WNT2B
UniProt Synonym Gene Names
WNT13
UniProt Entry Name
WNT2B_HUMAN
NCBI Protein Information
protein Wnt-2b

UniProt Comments for WNT2B

WNT2B: Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters. May be involved in normal development or differentiation as well as in carcinogenesis. Belongs to the Wnt family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 1p13

Cellular Component: proteinaceous extracellular matrix; extracellular space; extracellular region

Molecular Function: frizzled binding

Biological Process: lens development in camera-type eye; neuron differentiation; Wnt receptor signaling pathway; cell fate commitment; male gonad development; chondrocyte differentiation; Wnt receptor signaling pathway through beta-catenin; forebrain regionalization; cellular response to starvation
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Research Articles on WNT2B

1. ACSL5 mediates antiproliferative activities via Wnt2B palmitoylation with diminished Wnt activity. The molecular pathway is probably relevant for intestinal homeostasis, overwhelmed by other pathways in carcinogenesis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-WNT2B antibody

 Reference Product  PubMed Publications
 FZD5 antibody  >10 publications with WNT2B and FZD5
 FZD4 antibody  >9 publications with WNT2B and FZD4
 FZD6 antibody  >9 publications with WNT2B and FZD6
 FZD2 antibody  >7 publications with WNT2B and FZD2
 FZD10 antibody  >7 publications with WNT2B and FZD10
 LRP6 antibody  >6 publications with WNT2B and LRP6
 FZD3 antibody  >5 publications with WNT2B and FZD3
 FZD8 antibody  >4 publications with WNT2B and FZD8

Pathways associated with anti-WNT2B antibody

 Products by Pathway  Pathway Diagram
 Basal Cell Carcinoma Pathway antibodies  Basal Cell Carcinoma Pathway Diagram
 Basal Cell Carcinoma Pathway antibodies  Basal Cell Carcinoma Pathway Diagram
 Class B/2 (Secretin Family Receptors) Pathway antibodies  Class B/2 (Secretin Family Receptors) Pathway Diagram
 DNA Damage Response (only ATM Dependent) Pathway antibodies  DNA Damage Response (only ATM Dependent) Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 Hedgehog Signaling Pathway antibodies  Hedgehog Signaling Pathway Diagram
 Hedgehog Signaling Pathway antibodies  Hedgehog Signaling Pathway Diagram
 Hippo Signaling Pathway antibodies  Hippo Signaling Pathway Diagram

Diseases associated with anti-WNT2B antibody

 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >8 publications with WNT2B and Breast Neoplasms
 Lung Neoplasms Antibodies  >6 publications with WNT2B and Lung Neoplasms
 Disease Models, Animal Antibodies  >4 publications with WNT2B and Disease Models, Animal
 Inflammation Antibodies  >4 publications with WNT2B and Inflammation
 Necrosis Antibodies  >4 publications with WNT2B and Necrosis
 Neoplasm Metastasis Antibodies  >3 publications with WNT2B and Neoplasm Metastasis
 Neoplasms, Experimental Antibodies  >2 publications with WNT2B and Neoplasms, Experimental
 Ovarian Neoplasms Antibodies  >2 publications with WNT2B and Ovarian Neoplasms
 Congenital Abnormalities Antibodies  >2 publications with WNT2B and Congenital Abnormalities
 Neural Tube Defects Antibodies  >2 publications with WNT2B and Neural Tube Defects

Organs/Tissues associated with anti-WNT2B antibody

 Organ/Tissue Name  Pubmed Publications
 Embryonic Tissue Antibodies  >28 publications with WNT2B and Embryonic Tissue
 Eye Antibodies  >20 publications with WNT2B and Eye
 Brain Antibodies  >19 publications with WNT2B and Brain
 Lung Antibodies  >18 publications with WNT2B and Lung
 Kidney Antibodies  >8 publications with WNT2B and Kidney
 Testis Antibodies  >6 publications with WNT2B and Testis
 Skin Antibodies  >4 publications with WNT2B and Skin
 Prostate Antibodies  >4 publications with WNT2B and Prostate
 Placenta Antibodies  >4 publications with WNT2B and Placenta
 Ovary Antibodies  >3 publications with WNT2B and Ovary
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