• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

XPC Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6364006

This gene encodes a component of the nucleotide excision repair (NER) pathway. There are multiple components involved in the NER pathway, including Xeroderma pigmentosum (XP) A-G and V, Cockayne syndrome (CS) A and B, and trichothiodystrophy (TTD) group A,… More details

$1060 / 0.2 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
XPC, Polyclonal Antibody
Full Product Name
XPC, NT (XPC, XPCC, DNA repair protein complementing XP-C cells, Xeroderma pigmentosum group C-complementing protein, p125) (AP)
Product Gene Name
Product Synonym Names
XPC; XPCC; DNA repair protein complementing XP-C cells; Xeroderma pigmentosum group C-complementing protein; p125
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).
Purity/Purification
Purified by Protein A Affinity Chromatography.
Preparation and Storage
Store product at 4 degree C. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
15,712 Da
OMIM
phenotype 613208
3D Structure
ModBase 3D Structure for Q01831
Immunogen
XPC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 154-183 amino acids from the N-terminal region of human XPC.
Conjugate
AP
Note
Preservative Free

Product Categories/Family for anti-XPC antibody

Applications Tested/Suitable for anti-XPC antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-XPC antibody
WB: 1:100-500
ELISA: 1:1,000
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-XPC antibody

XPC Antibody (N-term) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the XPC antibody detected the XPC protein (arrow).
Rabbit Anti-XPC Polyclonal Antibody – Cat# MBS6364006

Product References and Citations for anti-XPC antibody

Gangwar, R., et al. J. Cancer Res. Clin. Oncol. (2009). In press: Agalliu, I., et al. Cancer Causes Control (2009). In press: Langie, S.A., et al. Br. J. Nutr., 1-12 (2009). In press: Young, R.P., et al. Postgrad Med J 85(1008):515-524(2009). Stern, M.C., et al. Cancer Res. 69(17):6857-6864(2009).

Other Notes

Small volumes of anti-XPC antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for XPC purchase

MBS6364006 is an antibody targeting XPC. Also known as XPC, NT (XPC, XPCC, DNA repair protein complementing XP-C cells, Xeroderma pigmentosum group C-complementing protein, p125) (AP). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for XPC. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI Related Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Synonym Full Names
XPC complex subunit, DNA damage recognition and repair factor
NCBI Official Symbol
XPC
NCBI Official Synonym Symbols
XP3; RAD4; XPCC; p125
UniProt Protein Name
DNA repair protein complementing XP-C cells
UniProt Synonym Protein Names
Xeroderma pigmentosum group C-complementing protein; p125
Protein Family
UniProt Gene Name
XPC
UniProt Synonym Gene Names
XPCC
UniProt Entry Name
XPC_HUMAN
NCBI Protein Information
DNA repair protein complementing XP-C cells

NCBI Summary for XPC

The protein encoded by this gene is a key component of the XPC complex, which plays an important role in the early steps of global genome nucleotide excision repair (NER). The encoded protein is important for damage sensing and DNA binding, and shows a preference for single-stranded DNA. Mutations in this gene or some other NER components can result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2017]
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000