Rabbit Anti-ZNF197 Polyclonal Antibody – Cat# MBS6365804

ZNF197 Antibody – Rabbit Polyclonal

Name: ZNF197 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6365804
Price: 1025 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6365804

ZNF197 product belongs to the zinc finger protein superfamily, members of which are regulatory proteins characterized by nucleic acid-binding zinc finger domains. The encoded protein contains 20 tandemly arrayed C2H2-type zinc fingers, a Kruppel-associated… More details

$1025 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

ZNF197, Polyclonal Antibody

Full Product Name

ZNF197, NT (ZNF197, ZKSCAN9, ZNF166, Zinc finger protein 197, Zinc finger protein with KRAB and SCAN domains 9, ZnF20, pVHL-associated KRAB domain-containing protein) (MaxLight 405)

Product Gene Name

anti-ZNF197 antibody

Product Synonym Names

ZNF197; ZKSCAN9; ZNF166; Zinc finger protein 197; Zinc finger protein with KRAB and SCAN domains 9; ZnF20; pVHL-associated KRAB domain-containing protein

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight405.

Purity/Purification

Purified by Protein A Affinity Chromatography.

Preparation and Storage

Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight405 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Molecular Weight

30,229 Da

3D Structure

ModBase 3D Structure for O14709

Immunogen

ZNF197 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 321-351 amino acids from the N-terminal region of human ZNF197.

Conjugate

MaxLight405

Note

Preservative Free

Product Categories/Family for anti-ZNF197 antibody

Antibodies; Transcription Factors; Zinc (Ring) Finger

Applications Tested/Suitable for anti-ZNF197 antibody

Immunohistochemistry (IHC), FLISA, Western Blot (WB)

Application Notes for anti-ZNF197 antibody

IHC: 1:50-100
FLISA: 1:1,000
WB: 1:100-500
Applications are based on unconjugated antibody.

Product References and Citations for anti-ZNF197 antibody

Li, Z., et al. EMBO J. 22(8):1857-1867(2003). Gonsky, R., et al. Nucleic Acids Res. 25(19):3823-3831(1997). Calabro, V., et al. Hum. Genet. 95(1):18-21(1995) Pengue, G., et al. Hum. Mol. Genet. 2(6):791-796(1993).

Other Notes

Small volumes of anti-ZNF197 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ZNF197 purchase

MBS6365804 is an antibody targeting ZNF197. Also known as ZNF197, NT (ZNF197, ZKSCAN9, ZNF166, Zinc finger protein 197, Zinc finger protein with KRAB and SCAN domains 9, ZnF20, pVHL-associated KRAB domain-containing protein) (MaxLight 405). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ZNF197. It may not necessarily be applicable to this product.

NCBI GI #

11386193

NCBI GeneID

10168

NCBI Accession #

NP_008922.1

UniProt Primary Accession #

O14709

UniProt Secondary Accession #

Q86VG0; B2RAH8

UniProt Related Accession #

O14709

GenBank Nucleotide #

NM_006991.4

NCBI Official Full Name

zinc finger protein 197 isoform 1

NCBI Official Synonym Full Names

zinc finger protein 197

NCBI Official Symbol

ZNF197

NCBI Official Synonym Symbols

P18; VHLaK; ZNF20; ZNF166; ZKSCAN9; ZSCAN41; D3S1363E

UniProt Protein Name

Zinc finger protein 197

UniProt Synonym Protein Names

Zinc finger protein with KRAB and SCAN domains 9; ZnF20; pVHL-associated KRAB domain-containing protein

Protein Family

Zinc finger protein

UniProt Gene Name

ZNF197

UniProt Synonym Gene Names

ZKSCAN9; ZNF166

UniProt Entry Name

ZN197_HUMAN

NCBI Protein Information

zinc finger protein 197

NCBI Summary for ZNF197

This gene product belongs to the zinc finger protein superfamily, members of which are regulatory proteins characterized by nucleic acid-binding zinc finger domains. The encoded protein contains 20 tandemly arrayed C2H2-type zinc fingers, a Kruppel-associated box (KRAB) domain, and a SCAN box. This transcript turns over rapidly and contains 3' UTR AUUUA motifs, which are often a hallmark of rapid turnover. It is overexpressed in some thyroid papillary carcinomas. This gene is located in a cluster of zinc finger genes at 3p21. [provided by RefSeq, Apr 2016]

UniProt Comments for ZNF197

ZNF197: May be involved in transcriptional regulation. Belongs to the krueppel C2H2-type zinc-finger protein family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription factor; DNA-binding; C2H2-type zinc finger protein

Chromosomal Location of Human Ortholog: 3p21

Cellular Component: nucleus

Molecular Function: DNA binding; metal ion binding; transcription factor activity

Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent

Research Articles on ZNF197

1. a novel pVHL-interacting protein that functions as a negative regulator of hypoxia-inducible factor-1a (HIF-1alpha) transactivation; demonstrate that the KRAB-A domain in VHLaK mediates pVHL binding and functions as a transcriptional repression module

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-ZNF197 antibody

Products by Pathway	Pathway Diagram
Gene Expression Pathway antibodies	Gene Expression Pathway Diagram
Generic Transcription Pathway antibodies	Generic Transcription Pathway Diagram

Organs/Tissues associated with anti-ZNF197 antibody

Organ/Tissue Name	Pubmed Publications
Vascular Antibodies	>1 publications with ZNF197 and Vascular