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ELOVL1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS541486

BIOTIN-Conjugated Elongation of very long chain fatty acids protein 1 AntibodyCatalyzes the first and rate-limiting reaction of the four that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ELOVL1, Polyclonal Antibody
Full Product Name
ELOVL1 Antibody BIOTIN-Conjugated
Product Gene Name
anti-ELOVL1 antibody
Product Synonym Names
3 keto acyl CoA synthase ELOVL1; CGI 88; Elongation of very long chain fatty acids (FEN1/Elo2 SUR4/Elo3 yeast) like 1; Elongation of very long chain fatty acids protein 1; ELOVL 1; ELOVL FA elongase 1; ELOVL fatty acid elongase 1; ELOVL1; Ssc1; Very-long-chain 3-oxoacyl-CoA synthase 1 antibody
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Monkey
Form/Format
BIOTIN-Conjugated
Concentration
0.5 ug/ul in antibody stabilization buffer (lot specific)
Preparation and Storage
-20 degree C for long term storage
Matching Pairs
Antibody: ELOVL1 (MBS541486)
Positive Control: ELOVL1 (MBS542730)
Antibody/Peptide Pairs
ELOVL1 peptide (MBS543627) is used for blocking the activity of ELOVL1 antibody (MBS541486)
Molecular Weight
29,485 Da
OMIM
611813
3D Structure
ModBase 3D Structure for Q9BW60
Immunogen
Synthetic peptide taken within amino acid region 148-198 on human Elongation of very long chain fatty acids protein 1.
Immunoglobulin
IgG
Expression
Ubiquitous
Molecular Function
Transferase; Fatty acid biosynthesis & metabolism; Lipid biosynthesis & metabolism
Structure
The di-lysine motif may confer endoplasmic reticulum localization.
Subcellular Location
Endoplasmic Reticulum membrane; Multi-pass membrane protein
Applications Tested/Suitable for anti-ELOVL1 antibody
ELISA (EIA), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)
Application Notes for anti-ELOVL1 antibody
ELISA: 1:10,000
Immunohistochemistry: 1:100
Immunoprecipitation: 1:200
Western Blot: 1:500

Other Notes

Small volumes of anti-ELOVL1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ELOVL1 purchase

MBS541486 is an antibody targeting ELOVL1. Also known as ELOVL1 Antibody BIOTIN-Conjugated. Reactive in Human, Monkey. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ELOVL1. It may not necessarily be applicable to this product.

NCBI GI #
373938452
NCBI GeneID
64834
NCBI Accession #
NP_001243331
UniProt Primary Accession #
Q9BW60
UniProt Secondary Accession #
Q53HT2; Q5JUY3; Q8WXU3; Q9NVD9; Q9Y396; B4DP24
UniProt Related Accession #
Q9BW60
GenBank Nucleotide #
NM_001256402.1
NCBI Official Full Name
elongation of very long chain fatty acids protein 1 isoform 3
NCBI Official Synonym Full Names
ELOVL fatty acid elongase 1
NCBI Official Symbol
ELOVL1
NCBI Official Synonym Symbols
Ssc1; CGI-88
UniProt Protein Name
Elongation of very long chain fatty acids protein 1
UniProt Synonym Protein Names
3-keto acyl-CoA synthase ELOVL1
Protein Family
Elongation of very long chain fatty acids protein
UniProt Gene Name
ELOVL1
UniProt Synonym Gene Names
ELOVL FA elongase 1
UniProt Entry Name
ELOV1_HUMAN
NCBI Protein Information
elongation of very long chain fatty acids protein 1

UniProt Comments for ELOVL1

ELOVL1: Condensing enzyme that catalyzes the synthesis of both saturated and monounsaturated very long chain fatty acids. Exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. Important for saturated C24:0 and monounsaturated C24:1 sphingolipid synthesis. Belongs to the ELO family.

Protein type: Membrane protein, multi-pass; Membrane protein, integral; EC 2.3.1.199

Chromosomal Location of Human Ortholog: 1p34.2

Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; integral to endoplasmic reticulum membrane; membrane

Molecular Function: fatty acid elongase activity; protein binding

Biological Process: fatty acid elongation, saturated fatty acid; linoleic acid metabolic process; sphingolipid biosynthetic process; very-long-chain fatty acid biosynthetic process
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Research Articles on ELOVL1

1. ELOV1 promotes very long-chain fatty acid accumulation X-linked adrenoleukodystrophy and is inhibited by CoA esters of bezafibrate and gemfibrozil.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-ELOVL1 antibody

 Products by Pathway  Pathway Diagram
 Fatty Acyl-CoA Biosynthesis Pathway antibodies  Fatty Acyl-CoA Biosynthesis Pathway Diagram
 Fatty Acid Biosynthesis, Elongation, Endoplasmic Reticulum Pathway antibodies  Fatty Acid Biosynthesis, Elongation, Endoplasmic Reticulum Pathway Diagram
 Fatty Acid Biosynthesis, Elongation, Endoplasmic Reticulum Pathway antibodies  Fatty Acid Biosynthesis, Elongation, Endoplasmic Reticulum Pathway Diagram
 Fatty Acid Elongation Pathway antibodies  Fatty Acid Elongation Pathway Diagram
 Fatty Acid Elongation Pathway antibodies  Fatty Acid Elongation Pathway Diagram
 Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway antibodies  Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway Diagram
 Linoleic Acid (LA) Metabolism Pathway antibodies  Linoleic Acid (LA) Metabolism Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 Synthesis Of Very Long-chain Fatty Acyl-CoAs Pathway antibodies  Synthesis Of Very Long-chain Fatty Acyl-CoAs Pathway Diagram

Diseases associated with anti-ELOVL1 antibody

 Disease Name  Pubmed Publications
 Fatty Liver Antibodies  >6 publications with ELOVL1 and Fatty Liver
 Inflammation Antibodies  >5 publications with ELOVL1 and Inflammation
 Congenital Abnormalities Antibodies  >2 publications with ELOVL1 and Congenital Abnormalities
 Breast Neoplasms Antibodies  >1 publications with ELOVL1 and Breast Neoplasms
 Liver Diseases Antibodies  >1 publications with ELOVL1 and Liver Diseases
 Weight Gain Antibodies  >1 publications with ELOVL1 and Weight Gain
 Disease Models, Animal Antibodies  >1 publications with ELOVL1 and Disease Models, Animal

Organs/Tissues associated with anti-ELOVL1 antibody

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >6 publications with ELOVL1 and Liver
 Skin Antibodies  >5 publications with ELOVL1 and Skin
 Brain Antibodies  >5 publications with ELOVL1 and Brain
 Blood Antibodies  >4 publications with ELOVL1 and Blood
 Eye Antibodies  >3 publications with ELOVL1 and Eye
 Adipose Tissue Antibodies  >3 publications with ELOVL1 and Adipose Tissue
 Connective Tissue Antibodies  >3 publications with ELOVL1 and Connective Tissue
 Thyroid Antibodies  >2 publications with ELOVL1 and Thyroid
 Lung Antibodies  >1 publications with ELOVL1 and Lung
 Bladder Antibodies  >1 publications with ELOVL1 and Bladder
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