Rabbit Anti-MARK1 Polyclonal Antibody – Cat# MBS7116574

Western Blot analysis of COS7 cells using MARK1/2/3/4 Polyclonal Antibody

MARK1 Antibody – Rabbit Polyclonal

Name: MARK1 Antibody; Polyclonal; Rabbit; Human/Mouse/Rat-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS7116574
Price: 185 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS7116574

MBS7116574 is an antibody targeting MARK1. Also known as MARK1/MARK2/MARK3/MARK4 Antibody. Reactive in Human, Mouse, Rat, Monkey. Host: Rabbit. More details

$185 / 0.05 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

MARK1/MARK2/MARK3/MARK4, Polyclonal Antibody

Full Product Name

MARK1/MARK2/MARK3/MARK4 Antibody

Product Gene Name

anti-MARK1 antibody

Product Synonym Names

MARK1; KIAA1477; MARK; Serine/threonine-protein kinase MARK1; MAP/microtubule affinity-regulating kinase 1; PAR1 homolog c; Par-1c; Par1c; MARK2; EMK1; Serine/threonine-protein kinase MARK2; ELKL motif kinase 1; EMK-1; MAP/microtubule affin

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human, Mouse, Rat, Monkey

Form/Format

Liquid; In Phosphate Buffered Saline, 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.

Purity/Purification

Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Preparation and Storage

Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

Molecular Weight

84,911 Da

OMIM

606511

3D Structure

ModBase 3D Structure for Q9P0L2

Immunogen

Synthesized peptide derived from human MARK1/2/3/4 around the non-phosphorylation site of T215.

Immunogen Species

Human

Conjugate

Non-conjugated

Product Categories/Family for anti-MARK1 antibody

Signal Transduction

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for anti-MARK1 antibody

Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA)

Application Notes for anti-MARK1 antibody

WB: 1:500-1:2000
IHC: 1:100-1:300
IF: 1:200-1:1000
ELISA: 1:10000

Other Notes

Small volumes of anti-MARK1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for MARK1. It may not necessarily be applicable to this product.

NCBI GI #

153791472

NCBI GeneID

4139

NCBI Accession #

NP_061120.3

UniProt Primary Accession #

Q9P0L2

UniProt Secondary Accession #

Q7KZI7; P27448; Q96L34

UniProt Related Accession #

Q9P0L2

GenBank Nucleotide #

NM_018650.4

NCBI Official Full Name

serine/threonine-protein kinase MARK1 isoform 2

NCBI Official Synonym Full Names

MAP/microtubule affinity-regulating kinase 1

NCBI Official Symbol

MARK1

NCBI Official Synonym Symbols

MARK; Par1c; Par-1c

UniProt Protein Name

Serine/threonine-protein kinase MARK1

UniProt Synonym Protein Names

MAP/microtubule affinity-regulating kinase 1; PAR1 homolog c; Par-1c; Par1c

Protein Family

Serine/threonine-protein kinase

UniProt Gene Name

MARK1

UniProt Synonym Gene Names

Par-1c; Par1c

UniProt Entry Name

MARK1_HUMAN

NCBI Protein Information

serine/threonine-protein kinase MARK1; PAR1 homolog c

UniProt Comments for MARK1

MARK1: a member of the CAMKL family of protein kinases. The MARK group of kinases is apparently involved in the control of cell polarity, microtubule stability and cancer. MARK1 forms a tight association with Tau in neurofibrillary tangles in Alzheimer disease tissue.

Protein type: Protein kinase, Ser/Thr (non-receptor); Kinase, protein; EC 2.7.11.26; EC 2.7.11.1; Protein kinase, CAMK; CAMK group; CAMKL family; MARK subfamily

Chromosomal Location of Human Ortholog: 1q41

Cellular Component: microtubule cytoskeleton; cytoskeleton; cytoplasm; plasma membrane

Molecular Function: protein serine/threonine kinase activity; phosphatidylinositol-4,5-bisphosphate binding; phosphatidylserine binding; tau-protein kinase activity; magnesium ion binding; ATP binding

Biological Process: Wnt receptor signaling pathway; neuron migration; cytoskeleton organization and biogenesis; protein amino acid phosphorylation

Research Articles on MARK1

1. the positioning of MARK/Par-1 at the crosstalk of regulating cytoskeletal dynamics allows its participation in neuronal polarity decisions. [review]

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-MARK1 antibody

Reference Product	PubMed Publications
MARK2 antibody	>79 publications with MARK1 and MARK2
MAP2 antibody	>8 publications with MARK1 and MAP2
MAP4 antibody	>6 publications with MARK1 and MAP4
STK11 antibody	>5 publications with MARK1 and STK11
MAPT antibody	>1 publications with MARK1 and MAPT

Pathways associated with anti-MARK1 antibody

Products by Pathway	Pathway Diagram
Regulation Of Microtubule Cytoskeleton Pathway antibodies	Regulation Of Microtubule Cytoskeleton Pathway Diagram

Diseases associated with anti-MARK1 antibody

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>19 publications with MARK1 and Nervous System Diseases
Brain Diseases Antibodies	>17 publications with MARK1 and Brain Diseases
Inflammation Antibodies	>9 publications with MARK1 and Inflammation
Necrosis Antibodies	>7 publications with MARK1 and Necrosis
Carcinoma, Hepatocellular Antibodies	>5 publications with MARK1 and Carcinoma, Hepatocellular
Liver Diseases Antibodies	>4 publications with MARK1 and Liver Diseases
Anemia Antibodies	>4 publications with MARK1 and Anemia
Fibrosis Antibodies	>4 publications with MARK1 and Fibrosis
Liver Cirrhosis Antibodies	>3 publications with MARK1 and Liver Cirrhosis
Stomach Neoplasms Antibodies	>3 publications with MARK1 and Stomach Neoplasms

Organs/Tissues associated with anti-MARK1 antibody

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>38 publications with MARK1 and Brain
Heart Antibodies	>16 publications with MARK1 and Heart
Lung Antibodies	>14 publications with MARK1 and Lung
Bone Antibodies	>8 publications with MARK1 and Bone
Kidney Antibodies	>6 publications with MARK1 and Kidney
Skin Antibodies	>5 publications with MARK1 and Skin
Stomach Antibodies	>4 publications with MARK1 and Stomach
Nerve Antibodies	>4 publications with MARK1 and Nerve
Bladder Antibodies	>3 publications with MARK1 and Bladder
Intestine Antibodies	>2 publications with MARK1 and Intestine