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AKAP6 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9609137

Function: Binds to type II regulatory subunits of protein kinase A and anchors/targets them to the nuclear membrane or sarcoplasmic reticulum. May act as an adapter for assembling multiprotein complexes.Subunit Structure: Interacts with RII subunit of PKA,… More details

$325 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
AKAP6, Polyclonal Antibody
Full Product Name
AKAP6 Antibody
Product Gene Name
Product Synonym Names
A kinase (PRKA) anchor protein 6; A kinase anchor protein 100; A kinase anchor protein 100 kDa; A kinase anchor protein 6; ADAP 100; ADAP 6; ADAP100; ADAP6; AKAP 100; AKAP 6; AKAP100; Human A kinase anchor protein AKAP100; KIAA0311; mAKAP; PRKA 6; PRKA6; Protein kinase A anchoring protein 6
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Concentration
1mg/ml (lot specific)
Specificity
AKAP6 antibody detects endogenous levels of total AKAP6
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Antibody/Peptide Pairs
AKAP6 peptide (MBS9627842) is used for blocking the activity of AKAP6 antibody (MBS9609137)
Molecular Weight
Observed: 257 kDa
Predicted: 257 kDa
3D Structure
ModBase 3D Structure for Q13023
Supply Chain Verification
Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available, please inquire.
Immunogen
A synthesized peptide derived from human AKAP6
Subcellular Location
Sarcoplasmic reticulum and nuclear membrane in heart muscle.
Tissue Specificity
Highly expressed in cardiac and skeletal muscle, followed by brain.
Conjugation
Unconjugated
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-AKAP6 antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes for anti-AKAP6 antibody
WB: 1:1000-3000
IHC: 1:200

Western Blot (WB) of anti-AKAP6 antibody

Western blot analysis of AKAP6 using HuvEc whole cell lysates
Rabbit Anti-AKAP6 Polyclonal Antibody – Cat# MBS9609137

Immunohistochemistry (IHC) of anti-AKAP6 antibody

MBS9609137 at 1/100 staining Mouse muscle tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22 degree C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
Rabbit Anti-AKAP6 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS9609137

Other Notes

Small volumes of anti-AKAP6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AKAP6 purchase

MBS9609137 is an antibody targeting AKAP6. Also known as AKAP6 Antibody. Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for AKAP6. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
A-kinase anchor protein 6
NCBI Official Synonym Full Names
A-kinase anchoring protein 6
NCBI Official Symbol
AKAP6
NCBI Official Synonym Symbols
ADAP6; PRKA6; mAKAP; ADAP100; AKAP100
UniProt Protein Name
A-kinase anchor protein 6
UniProt Synonym Protein Names
A-kinase anchor protein 100 kDa; AKAP 100; Protein kinase A-anchoring protein 6; PRKA6; mAKAP
UniProt Gene Name
AKAP6
UniProt Synonym Gene Names
AKAP100; KIAA0311; AKAP-6; AKAP 100; PRKA6
NCBI Protein Information
A-kinase anchor protein 6

NCBI Summary for AKAP6

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is highly expressed in various brain regions and cardiac and skeletal muscle. It is specifically localized to the sarcoplasmic reticulum and nuclear membrane, and is involved in anchoring PKA to the nuclear membrane or sarcoplasmic reticulum. [provided by RefSeq, Jul 2008]
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UniProt Comments for AKAP6

Binds to type II regulatory subunits of protein kinase A and anchors/targets them to the nuclear membrane or sarcoplasmic reticulum. May act as an adapter for assembling multiprotein complexes.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-AKAP6 antibody

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