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ALB Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6462195

MBS6462195 is an antibody targeting ALB. Also known as ALB, CT (Serum Albumin, GIG20, GIG42, PRO0903, PRO1708, PRO2044, PRO2619, PRO2675, UNQ696/PRO1341, DKFZp779N1935, PRO0883, PRO1341) (Biotin). Reactive in Human, Mouse. Host: Rabbit. More details

$1060 / 0.2 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ALB, Polyclonal Antibody
Full Product Name
ALB, CT (Serum Albumin, GIG20, GIG42, PRO0903, PRO1708, PRO2044, PRO2619, PRO2675, UNQ696/PRO1341, DKFZp779N1935, PRO0883, PRO1341) (Biotin)
Product Gene Name
anti-ALB antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
Purity/Purification
Purified by Ammonium Sulfate Precipitation.
Specificity
Recognizes human ALB. Species Crossreactivity: mouse.
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
68kDa (597aa) 50-70kDa (SDS-PAGE under reducing conditions.)
OMIM
103600
3D Structure
ModBase 3D Structure for P02768
Immunogen
Synthetic peptide selected from the C-terminal region of human ALB (KLH).
Conjugate
Biotin
Note
Preservative Free

Product Categories/Family for anti-ALB antibody

Antibodies; Albumin
Applications Tested/Suitable for anti-ALB antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-ALB antibody
WB: 1:50-1:100
ELISA: 1:1,000
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-ALB antibody

Western blot analysis of ALB antibody (C-term) in mouse liver tissue lysates (35ug/lane). ALB (arrow) was detected using the purified Pab.
Rabbit Anti-ALB Polyclonal Antibody – Cat# MBS6462195

Western Blot (WB) of anti-ALB antibody

ALB Antibody (C-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the ALB antibody detected the ALB protein (arrow).
Rabbit Anti-ALB Polyclonal Antibody, Western Blot (WB) – Cat# MBS6462195

Immunofluorescence (IF) of anti-ALB antibody

Confocal immunofluorescent analysis of ALB Antibody (C-term) with 293 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
Rabbit Anti-ALB Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS6462195

Flow Cytometry (FC/FACS) of anti-ALB antibody

ALB Antibody (C-term) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Rabbit Anti-ALB Polyclonal Antibody, Flow Cytometry (FC/FACS) – Cat# MBS6462195

Product References and Citations for anti-ALB antibody

1. Liu, Z., Biophys. J. 96(10), 3917-3925 (2009). 2. Minchiotti, L., Hum. Mutat. 29(8), 1007-1016 (2008).

Other Notes

Small volumes of anti-ALB antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ALB. It may not necessarily be applicable to this product.

NCBI GI #
4502027
NCBI GeneID
213
NCBI Accession #
NP_000468
UniProt Primary Accession #
P02768
UniProt Secondary Accession #
O95574; P04277; Q13140; Q645G4; Q68DN5; Q6UXK4; Q86YG0; Q8IUK7; Q9P157; Q9P1I7; E7ESS9
UniProt Related Accession #
P02768
GenBank Nucleotide #
NM_000477.6
NCBI Official Full Name
serum albumin preproprotein
NCBI Official Synonym Full Names
albumin
NCBI Official Symbol
ALB
NCBI Official Synonym Symbols
HSA; PRO0883; PRO0903; PRO1341
UniProt Protein Name
Serum albumin
Protein Family
Serum albumin
UniProt Gene Name
ALB
UniProt Entry Name
ALBU_HUMAN
NCBI Protein Information
serum albumin

NCBI Summary for ALB

This gene encodes the most abundant protein in human blood. This protein functions in the regulation of blood plasma colloid osmotic pressure and acts as a carrier protein for a wide range of endogenous molecules including hormones, fatty acids, and metabolites, as well as exogenous drugs. Additionally, this protein exhibits an esterase-like activity with broad substrate specificity. The encoded preproprotein is proteolytically processed to generate the mature protein. A peptide derived from this protein, EPI-X4, is an endogenous inhibitor of the CXCR4 chemokine receptor. [provided by RefSeq, Jul 2016]
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UniProt Comments for ALB

albumin: Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc. Plasma. Belongs to the ALB/AFP/VDB family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Carrier; Secreted

Chromosomal Location of Human Ortholog: 4q13.3

Cellular Component: extracellular space; protein complex; extracellular region; basement membrane; nucleus

Molecular Function: antioxidant activity; toxin binding; protein binding; copper ion binding; enzyme binding; DNA binding; zinc ion binding; chaperone binding; drug binding; oxygen binding; fatty acid binding; pyridoxal phosphate binding

Biological Process: platelet activation; receptor-mediated endocytosis; sodium-independent organic anion transport; bile acid metabolic process; maintenance of mitochondrion localization; lipoprotein metabolic process; hemolysis by symbiont of host red blood cells; cellular response to starvation; response to organic substance; response to mercury ion; bile acid and bile salt transport; retinal homeostasis; platelet degranulation; transport; negative regulation of programmed cell death; blood coagulation; transmembrane transport; positive regulation of circadian sleep/wake cycle, non-REM sleep; response to nutrient; negative regulation of apoptosis

Disease: Analbuminemia; Hyperthyroxinemia, Familial Dysalbuminemic
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Research Articles on ALB

1. these peptides are identified as fragments of albumin. The isolated fragments activate MRGPRX2 and degranulate MRGPRX2 expressing LAD 2 cells in dose-dependent manner. The isolated basic peptides generated from human albumin are able to degranulate mast cells via the MRGPRX2.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-ALB antibody

 Products by Pathway  Pathway Diagram
 Bile Acid And Bile Salt Metabolism Pathway antibodies  Bile Acid And Bile Salt Metabolism Pathway Diagram
 Binding And Uptake Of Ligands By Scavenger Receptors Pathway antibodies  Binding And Uptake Of Ligands By Scavenger Receptors Pathway Diagram
 Defective SLCO1B1 Causes Hyperbilirubinemia, Rotor Type (HBLRR) Pathway antibodies  Defective SLCO1B1 Causes Hyperbilirubinemia, Rotor Type (HBLRR) Pathway Diagram
 Defective SLCO1B3 Causes Hyperbilirubinemia, Rotor Type (HBLRR) Pathway antibodies  Defective SLCO1B3 Causes Hyperbilirubinemia, Rotor Type (HBLRR) Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Disorders Of Transmembrane Transporters Pathway antibodies  Disorders Of Transmembrane Transporters Pathway Diagram
 FOXA2 And FOXA3 Transcription Factor Networks Pathway antibodies  FOXA2 And FOXA3 Transcription Factor Networks Pathway Diagram
 Folate Metabolism Pathway antibodies  Folate Metabolism Pathway Diagram
 HDL-mediated Lipid Transport Pathway antibodies  HDL-mediated Lipid Transport Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram

Diseases associated with anti-ALB antibody

 Disease Name  Pubmed Publications
 Kidney Diseases Antibodies  >253 publications with ALB and Kidney Diseases
 Proteinuria Antibodies  >172 publications with ALB and Proteinuria
 Cardiovascular Diseases Antibodies  >167 publications with ALB and Cardiovascular Diseases
 Disease Models, Animal Antibodies  >162 publications with ALB and Disease Models, Animal
 Liver Cirrhosis Antibodies  >131 publications with ALB and Liver Cirrhosis
 Respiratory Tract Diseases Antibodies  >121 publications with ALB and Respiratory Tract Diseases
 Brain Diseases Antibodies  >88 publications with ALB and Brain Diseases
 Kidney Failure, Chronic Antibodies  >68 publications with ALB and Kidney Failure, Chronic
 Hypertension Antibodies  >67 publications with ALB and Hypertension
 Nephritis Antibodies  >48 publications with ALB and Nephritis

Organs/Tissues associated with anti-ALB antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >1251 publications with ALB and Blood
 Liver Antibodies  >695 publications with ALB and Liver
 Kidney Antibodies  >347 publications with ALB and Kidney
 Lung Antibodies  >122 publications with ALB and Lung
 Heart Antibodies  >111 publications with ALB and Heart
 Muscle Antibodies  >107 publications with ALB and Muscle
 Spleen Antibodies  >49 publications with ALB and Spleen
 Embryonic Tissue Antibodies  >42 publications with ALB and Embryonic Tissue
 Placenta Antibodies  >8 publications with ALB and Placenta
 Uterus Antibodies  >5 publications with ALB and Uterus
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