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ALDH9A1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9210282

ALDH9A1 belongs to the aldehyde dehydrogenase family of proteins. The protein has a high activity for oxidation of gamma-aminobutyraldehyde and other amino aldehydes. The enzyme catalyzes the dehydrogenation of gamma-aminobutyraldehyde to gamma-aminobutyric… More details

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Product Overview

Online Datasheet in PDF
Product Name
ALDH9A1, Polyclonal Antibody
Full Product Name
ALDH9A1 Antibody (N-term)
Product Gene Name
anti-ALDH9A1 antibody
Product Synonym Names
4-trimethylaminobutyraldehyde dehydrogenase; TMABADH; Aldehyde dehydrogenase E3 isozyme; Aldehyde dehydrogenase family 9 member A1; Gamma-aminobutyraldehyde dehydrogenase; R-aminobutyraldehyde dehydrogenase; ALDH9A1; ALDH4; ALDH7; ALDH9
Clonality
Polyclonal
Isotype
Rabbit Ig
Host
Rabbit
Species Reactivity
Human, mouse
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Purity/Purification
Purified Rabbit Polyclonal Antibody (Pab)
Concentration
Vial Concentration: 2 (lot specific)
Specificity
This ALDH9A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 4-34 amino acids from the N-terminal region of human ALDH9A1.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
ALDH9A1 peptide (MBS9227318) is used for blocking the activity of ALDH9A1 antibody (MBS9210282)
Molecular Weight
53802
Immunogen Sequence Positions
4-34
OMIM
602733
3D Structure
ModBase 3D Structure for P49189
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN

Product Categories/Family for anti-ALDH9A1 antibody

Metabolism; Neuroscience; Signal Transduction
Applications Tested/Suitable for anti-ALDH9A1 antibody
Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC)
Application Notes for anti-ALDH9A1 antibody
WB~~1:1000

Western Blot (WB) of anti-ALDH9A1 antibody

Western blot analysis of anti-ALDH9A1 Antibody (N-term) in mouse kidney tissue lysates (35ug/lane). ALDH9A1(arrow) was detected using the purified Pab.
Rabbit Anti-ALDH9A1 Polyclonal Antibody – Cat# MBS9210282

Immunohistochemistry (IHC) of anti-ALDH9A1 antibody

Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with ALDH9A1 antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Rabbit Anti-ALDH9A1 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS9210282

Product References and Citations for anti-ALDH9A1 antibody

Cheung,C.L., Hum. Mol. Genet. 18 (4), 679-687 (2009)
Vaz,F.M., J. Biol. Chem. 275 (10), 7390-7394 (2000)
Lin,S.W., Genomics 34 (3), 376-380 (1996)

Other Notes

Small volumes of anti-ALDH9A1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ALDH9A1 purchase

MBS9210282 is an antibody targeting ALDH9A1. Also known as ALDH9A1 Antibody (N-term). Reactive in Human, mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for ALDH9A1. It may not necessarily be applicable to this product.

NCBI GI #
115387104
NCBI GeneID
223
NCBI Accession #
NP_000687.3
UniProt Primary Accession #
P49189
UniProt Secondary Accession #
Q5VV90; Q6LCL1; Q9NZT7; B2R6X1; B4DXY7
UniProt Related Accession #
P49189
GenBank Nucleotide #
NM_000696.3
NCBI Official Full Name
4-trimethylaminobutyraldehyde dehydrogenase
NCBI Official Synonym Full Names
aldehyde dehydrogenase 9 family, member A1
NCBI Official Symbol
ALDH9A1
NCBI Official Synonym Symbols
E3; ALDH4; ALDH7; ALDH9; TMABADH
UniProt Protein Name
4-trimethylaminobutyraldehyde dehydrogenase
UniProt Synonym Protein Names
Aldehyde dehydrogenase E3 isozyme; Aldehyde dehydrogenase family 9 member A1 (EC:1.2.1.3); Gamma-aminobutyraldehyde dehydrogenase (EC:1.2.1.19); R-aminobutyraldehyde dehydrogenase
Protein Family
4-trimethylaminobutyraldehyde dehydrogenase
UniProt Gene Name
ALDH9A1
UniProt Synonym Gene Names
ALDH4; ALDH7; ALDH9; TMABADH
UniProt Entry Name
AL9A1_HUMAN
NCBI Protein Information
4-trimethylaminobutyraldehyde dehydrogenase

NCBI Summary for ALDH9A1

This protein belongs to the aldehyde dehydrogenase family of proteins. It has a high activity for oxidation of gamma-aminobutyraldehyde and other amino aldehydes. The enzyme catalyzes the dehydrogenation of gamma-aminobutyraldehyde to gamma-aminobutyric acid (GABA). This isozyme is a tetramer of identical 54-kD subunits. [provided by RefSeq, Jul 2008]
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UniProt Comments for ALDH9A1

ALDH9A1: Converts gamma-trimethylaminobutyraldehyde into gamma- butyrobetaine. Catalyzes the irreversible oxidation of a broad range of aldehydes to the corresponding acids in an NAD-dependent reaction. Belongs to the aldehyde dehydrogenase family.

Protein type: Amino Acid Metabolism - valine, leucine and isoleucine degradation; Amino Acid Metabolism - tryptophan; Carbohydrate Metabolism - pyruvate; EC 1.2.1.47; Carbohydrate Metabolism - propanoate; Other Amino Acids Metabolism - beta-alanine; Amino Acid Metabolism - lysine degradation; Carbohydrate Metabolism - butanoate; Oxidoreductase; Carbohydrate Metabolism - ascorbate and aldarate; Mitochondrial; Amino Acid Metabolism - arginine and proline; Secondary Metabolites Metabolism - limonene and pinene degradation; Lipid Metabolism - glycerolipid; Lipid Metabolism - fatty acid; Carbohydrate Metabolism - glycolysis and gluconeogenesis; EC 1.2.1.3; Amino Acid Metabolism - histidine

Chromosomal Location of Human Ortholog: 1q23.1

Cellular Component: mitochondrion; cytoplasm; cytosol

Molecular Function: 1-pyrroline dehydrogenase activity; amine binding; aldehyde dehydrogenase (NAD) activity; protein homodimerization activity; aminobutyraldehyde dehydrogenase activity; 4-trimethylammoniobutyraldehyde dehydrogenase activity; 3-chloroallyl aldehyde dehydrogenase activity; NAD binding

Biological Process: hormone metabolic process; aldehyde metabolic process; kidney development; liver development; carnitine biosynthetic process; neurotransmitter biosynthetic process
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Research Articles on ALDH9A1

1. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-ALDH9A1 antibody

 Reference Product  PubMed Publications
 BBOX1 antibody  >2 publications with ALDH9A1 and BBOX1
 ADH4 antibody  >1 publications with ALDH9A1 and ADH4
 ABAT antibody  >1 publications with ALDH9A1 and ABAT

Diseases associated with anti-ALDH9A1 antibody

 Disease Name  Pubmed Publications
 Fatty Liver Antibodies  >3 publications with ALDH9A1 and Fatty Liver
 Fibrosis Antibodies  >1 publications with ALDH9A1 and Fibrosis
 Drug-Related Side Effects and Adverse Reactions Antibodies  >1 publications with ALDH9A1 and Drug-Related Side Effects and Adverse Reactions
 Disease Models, Animal Antibodies  >1 publications with ALDH9A1 and Disease Models, Animal
 Inflammation Antibodies  >1 publications with ALDH9A1 and Inflammation
 Liver Neoplasms Antibodies  >1 publications with ALDH9A1 and Liver Neoplasms
 Poisoning Antibodies  >1 publications with ALDH9A1 and Poisoning

Organs/Tissues associated with anti-ALDH9A1 antibody

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >6 publications with ALDH9A1 and Liver
 Blood Antibodies  >2 publications with ALDH9A1 and Blood
 Embryonic Tissue Antibodies  >2 publications with ALDH9A1 and Embryonic Tissue
 Kidney Antibodies  >2 publications with ALDH9A1 and Kidney
 Ovary Antibodies  >2 publications with ALDH9A1 and Ovary
 Brain Antibodies  >2 publications with ALDH9A1 and Brain
 Adipose Tissue Antibodies  >1 publications with ALDH9A1 and Adipose Tissue
 Connective Tissue Antibodies  >1 publications with ALDH9A1 and Connective Tissue
 Skin Antibodies  >1 publications with ALDH9A1 and Skin
 Lung Antibodies  >1 publications with ALDH9A1 and Lung
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