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AMH Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6273232

MBS6273232 is an antibody targeting AMH. Also known as AMH, ID (AMH, MIF, Muellerian-inhibiting factor, Anti-Muellerian hormone, Muellerian-inhibiting substance) (MaxLight 650). Reactive in Human, Mouse. Host: Rabbit. More details

$1060 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
AMH, Polyclonal Antibody
Full Product Name
AMH, ID (AMH, MIF, Muellerian-inhibiting factor, Anti-Muellerian hormone, Muellerian-inhibiting substance) (MaxLight 650)
Product Gene Name
anti-AMH antibody
Product Synonym Names
AMH; MIF; Muellerian-inhibiting factor; Anti-Muellerian hormone; Muellerian-inhibiting substance
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight650.
Purity/Purification
Purified by Protein A and Peptide Affinity Chromatography.
Specificity
Recognizes human AMH. Species crossreactivity: mouse
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight650 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
59,195 Da
OMIM
261550
3D Structure
ModBase 3D Structure for P03971
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 424-451 in the central region of human AMH, Swiss/UniProt Accession: P03971.
Conjugate
MaxLight650
Note
Preservative Free

Product Categories/Family for anti-AMH antibody

Antibodies; Hormones; Steroids
Applications Tested/Suitable for anti-AMH antibody
Immunohistochemistry (IHC) Paraffin, FLISA, Western Blot (WB), Flow Cytometry (FC/FACS)
Application Notes for anti-AMH antibody
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-AMH antibody

Western Blot analysis in 293 cell line lysates (35ug/lane) usingMBS6000643. AMH (arrow) was detected usingMBS6000643.
Rabbit Anti-AMH Polyclonal Antibody – Cat# MBS6273232

Western Blot (WB) of anti-AMH antibody

Western Blot analysis in mouse liver tissue lysates (35ug/lane) usingMBS6000643. AMH (arrow) was detected usingMBS6000643.
Rabbit Anti-AMH Polyclonal Antibody, Western Blot (WB) – Cat# MBS6273232

Immunohistochemistry (IHC) of anti-AMH antibody

Immunohistochemistry analysis in formalin fixed and paraffin embedded prostate carcinoma using MBS6000643 followed by peroxidase conjugation of the secondary antibody and DAB staining.
Rabbit Anti-AMH Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS6273232

Flow Cytometry (FC/FACS) of anti-AMH antibody

Flow Cytometry analysis of 293 cells (right histogram) using MBS6000643 compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Rabbit Anti-AMH Polyclonal Antibody, Flow Cytometry (FC/FACS) – Cat# MBS6273232

Other Notes

Small volumes of anti-AMH antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for AMH. It may not necessarily be applicable to this product.

NCBI GI #
157266298
NCBI GeneID
268
NCBI Accession #
NP_000470.2
UniProt Primary Accession #
P03971
UniProt Secondary Accession #
O75246; Q6GTN3
UniProt Related Accession #
P03971
GenBank Nucleotide #
NM_000479.3
NCBI Official Full Name
muellerian-inhibiting factor
NCBI Official Synonym Full Names
anti-Mullerian hormone
NCBI Official Symbol
AMH
NCBI Official Synonym Symbols
MIF; MIS
UniProt Protein Name
Muellerian-inhibiting factor
UniProt Synonym Protein Names
Anti-Muellerian hormone; AMH; Muellerian-inhibiting substance
Protein Family
Muellerian-inhibiting factor
UniProt Gene Name
AMH
UniProt Synonym Gene Names
MIF; AMH; MIS
UniProt Entry Name
MIS_HUMAN
NCBI Protein Information
muellerian-inhibiting factor; anti-Muellerian hormone; Mullerian inhibiting factor; Mullerian inhibiting substance; muellerian-inhibiting substance

NCBI Summary for AMH

Anti-Mullerian hormone is a member of the transforming growth factor-beta gene family which mediates male sexual differentiation. Anti-Mullerian hormone causes the regression of Mullerian ducts which would otherwise differentiate into the uterus and fallopian tubes. Some mutations in the anti-Mullerian hormone result in persistent Mullerian duct syndrome. [provided by RefSeq, Jul 2008]
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UniProt Comments for AMH

AMH: This glycoprotein, produced by the Sertoli cells of the testis, causes regression of the Muellerian duct. It is also able to inhibit the growth of tumors derived from tissues of Muellerian duct origin. Defects in AMH are the cause of persistent Muellerian duct syndrome type 1 (PMDS1). PMDS1 is a form of male pseudohermaphroditism characterized by a failure of Muellerian duct regression in otherwise normal males. Belongs to the TGF-beta family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: extracellular space; cytoplasm; extracellular region

Molecular Function: growth factor activity; hormone activity; transforming growth factor beta receptor binding; receptor binding

Biological Process: response to drug; sex determination; Mullerian duct regression; cell-cell signaling; gonadal mesoderm development; preantral ovarian follicle growth; sex differentiation; response to organic cyclic substance; urogenital system development; activation of NF-kappaB transcription factor; aging

Disease: Persistent Mullerian Duct Syndrome, Types I And Ii
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Research Articles on AMH

1. Serum AMH was significantly lower 2 days and 3 months following hysterectomy compared with the pre-operative level. Hysterectomy may have a more lasting adverse effect on ovarian reserve than myomectomy

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-AMH antibody

 Reference Product  PubMed Publications
 FSH antibody  >545 publications with AMH and FSH
 SOX9 antibody  >75 publications with AMH and SOX9
 AMHR2 antibody  >32 publications with AMH and AMHR2
 GATA4 antibody  >21 publications with AMH and GATA4
 KITLG antibody  >13 publications with AMH and KITLG
 ZFPM2 antibody  >3 publications with AMH and ZFPM2
 SMAD5 antibody  >3 publications with AMH and SMAD5
 SMAD9 antibody  >1 publications with AMH and SMAD9
 ACVR1 antibody  >1 publications with AMH and ACVR1

Pathways associated with anti-AMH antibody

 Products by Pathway  Pathway Diagram
 ALK2 Signaling Events Pathway antibodies  ALK2 Signaling Events Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Hippo Signaling Pathway antibodies  Hippo Signaling Pathway Diagram
 Hippo Signaling Pathway antibodies  Hippo Signaling Pathway Diagram
 TGF-beta Signaling Pathway antibodies  TGF-beta Signaling Pathway Diagram
 TGF-beta Signaling Pathway antibodies  TGF-beta Signaling Pathway Diagram
 CAMP Signaling Pathway antibodies  CAMP Signaling Pathway Diagram
 CAMP Signaling Pathway antibodies  CAMP Signaling Pathway Diagram

Diseases associated with anti-AMH antibody

 Disease Name  Pubmed Publications
 Female Urogenital Diseases Antibodies  >549 publications with AMH and Female Urogenital Diseases
 Gonadal Disorders Antibodies  >449 publications with AMH and Gonadal Disorders
 Neoplasms Antibodies  >309 publications with AMH and Neoplasms
 Ovarian Diseases Antibodies  >306 publications with AMH and Ovarian Diseases
 Infertility, Female Antibodies  >264 publications with AMH and Infertility, Female
 Urogenital Abnormalities Antibodies  >151 publications with AMH and Urogenital Abnormalities
 Genital Diseases, Male Antibodies  >129 publications with AMH and Genital Diseases, Male
 Disorders of Sex Development Antibodies  >129 publications with AMH and Disorders of Sex Development
 Infertility, Male Antibodies  >76 publications with AMH and Infertility, Male
 Testicular Diseases Antibodies  >65 publications with AMH and Testicular Diseases

Organs/Tissues associated with anti-AMH antibody

 Organ/Tissue Name  Pubmed Publications
 Testis Antibodies  >319 publications with AMH and Testis
 Uterus Antibodies  >66 publications with AMH and Uterus
 Brain Antibodies  >50 publications with AMH and Brain
 Embryonic Tissue Antibodies  >47 publications with AMH and Embryonic Tissue
 Lung Antibodies  >19 publications with AMH and Lung
 Prostate Antibodies  >12 publications with AMH and Prostate
 Intestine Antibodies  >9 publications with AMH and Intestine
 Eye Antibodies  >4 publications with AMH and Eye
 Stomach Antibodies  >2 publications with AMH and Stomach
 Mammary Gland Antibodies  >2 publications with AMH and Mammary Gland
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