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BLOC1S1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS9133996
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MBS9133996 is an antibody targeting BLOC1S1. Also known as BLOC1S1 Polyclonal Antibody. Reactive in Human, Mouse. Host: Rabbit. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
BLOC1S1, Polyclonal Antibody
Full Product Name
BLOC1S1 Polyclonal Antibody
Product Gene Name
Product Synonym Names
BLOS1; BORCS1; GCN5L1; MICoA; RT14
Immunogen Sequence
MLSRLLKEHQ AKQNERKELQ EKRRREAITA ATCLTEALVD HLNVGVAQAY MNQRKLDHEV KTLQVQAAQF AKQTGQWIGM VENFNQALKE IGDVENWARS IELDMRTIAT ALEYVYKGQL QSAPS
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Purity/Purification
Affinity Purification
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles.
Molecular Weight
14kDa/17kDa
OMIM
D64007 mRNA
3D Structure
ModBase 3D Structure for P78537
Immunogen
Recombinant protein of human BLOC1S1
Immunogen Species
Human
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Cellular Location
Cytoplasm, Mitochondrion intermembrane space, Mitochondrion matrix, cytosol

Product Categories/Family for anti-BLOC1S1 antibody

ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-BLOC1S1 antibody
Western Blot (WB)
Application Notes for anti-BLOC1S1 antibody
WB: 1:500 - 1:2000

Other Notes

Small volumes of anti-BLOC1S1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for BLOC1S1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
biogenesis of lysosome-related organelles complex 1 subunit 1
NCBI Official Synonym Full Names
biogenesis of lysosomal organelles complex 1 subunit 1
NCBI Official Symbol
BLOC1S1
NCBI Official Synonym Symbols
RT14; BLOS1; MICoA; BORCS1; GCN5L1
UniProt Protein Name
Biogenesis of lysosome-related organelles complex 1 subunit 1
UniProt Synonym Protein Names
GCN5-like protein 1; Protein RT14
UniProt Gene Name
BLOC1S1
UniProt Synonym Gene Names
BLOS1; GCN5L1; RT14; BLOC-1 subunit 1
NCBI Protein Information
biogenesis of lysosome-related organelles complex 1 subunit 1

NCBI Summary for BLOC1S1

BLOC1S1 is a component of the ubiquitously expressed BLOC1 multisubunit protein complex. BLOC1 is required for normal biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules (Starcevic and Dell'Angelica, 2004 [PubMed 15102850]).[supplied by OMIM, Mar 2008]
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UniProt Comments for BLOC1S1

Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension (PubMed:17182842). As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor (PubMed:25898167).
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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