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CAMK4 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Special Promotion Catalog #: MBS129911
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The product of this gene belongs to the serine/threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This enzyme is a multifunctional serine/threonine protein kinase with limited tissue distribution, that has been… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CAMK4, Polyclonal Antibody
Full Product Name
CAMK4 Polyclonal Antibody
Product Gene Name
anti-CAMK4 antibody
Product Synonym Names
IV; caMK; CaMK IV; CaMK-GR
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Purity/Purification
Affinity Purification
Concentration
1mg/ml (lot specific)
Preparation and Storage
Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Molecular Weight
473
OMIM
114080
3D Structure
ModBase 3D Structure for Q16566
Species
Human
Immunogen
Recombinant protein of human CAMK4
Calculated Molecular Weight
52kDa

Product Categories/Family for anti-CAMK4 antibody

Polyclonal
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-CAMK4 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes for anti-CAMK4 antibody
WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
IF: 1:50 - 1:200

Western Blot (WB) of anti-CAMK4 antibody

Western blot analysis of extracts of various cell lines, using CAMK4 antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 30s.
Rabbit Anti-CAMK4 Polyclonal Antibody – Cat# MBS129911

Immunofluorescence (IF) of anti-CAMK4 antibody

Immunofluorescence analysis of U2OS cells using CAMK4 antibody. Blue: DAPI for nuclear staining.
Rabbit Anti-CAMK4 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS129911

Other Notes

Small volumes of anti-CAMK4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CAMK4 purchase

MBS129911 is an antibody targeting CAMK4. Also known as CAMK4 Polyclonal Antibody. Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CAMK4. It may not necessarily be applicable to this product.

NCBI GI #
2499586
NCBI GeneID
814
NCBI Accession #
Q16566.1
UniProt Primary Accession #
Q16566
UniProt Secondary Accession #
D3DSZ7
UniProt Related Accession #
Q16566
NCBI Official Full Name
Calcium/calmodulin-dependent protein kinase type IV
NCBI Official Synonym Full Names
calcium/calmodulin-dependent protein kinase IV
NCBI Official Symbol
CAMK4
NCBI Official Synonym Symbols
IV; caMK; CaMK IV; CaMK-GR
UniProt Protein Name
Calcium/calmodulin-dependent protein kinase type IV
UniProt Synonym Protein Names
CaM kinase-GR
Protein Family
Calcium/calmodulin-dependent protein kinase
UniProt Gene Name
CAMK4
UniProt Synonym Gene Names
CAMK; CAMK-GR; CAMKIV; CaMK IV
UniProt Entry Name
KCC4_HUMAN
NCBI Protein Information
calcium/calmodulin-dependent protein kinase type IV; CAM kinase IV; caM kinase-GR; CAM kinase- GR; brain Ca++-calmodulin-dependent protein kinase type IV; brain Ca(2+)-calmodulin-dependent protein kinase type IV; calcium/calmodulin-dependent protein kinase type IV catalytic chain

UniProt Comments for CAMK4

CAMK4: a protein kinase of the CAMK1 family. Implicated in transcriptional regulation in lymphocytes, neurons and male germ cells. Two alternatively sliced isoforms have been described.

Protein type: Kinase, protein; Protein kinase, CAMK; EC 2.7.11.17; Protein kinase, Ser/Thr (non-receptor); CAMK group; CAMK1 family

Chromosomal Location of Human Ortholog: 5q21.3

Cellular Component: nucleoplasm; nucleolus; cytosol

Molecular Function: calmodulin binding; calmodulin-dependent protein kinase activity; ATP binding

Biological Process: epidermal growth factor receptor signaling pathway; mitochondrion organization and biogenesis; fibroblast growth factor receptor signaling pathway; nerve growth factor receptor signaling pathway; regulation of T cell differentiation in the thymus; positive regulation of transcription, DNA-dependent; organelle organization and biogenesis; nucleocytoplasmic transport; myeloid dendritic cell differentiation; signal transduction; protein amino acid phosphorylation; positive regulation of protein export from nucleus; synaptic transmission; regulation of osteoclast differentiation; long-term memory; phospholipase C activation; innate immune response; nerve-nerve synaptic transmission; inflammatory response; myeloid dendritic cell cytokine production
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Research Articles on CAMK4

1. An imbalance of specific isoforms of CYFIP1, an FMRP interaction partner, and CAMK4, a transcriptional regulator of the FMRP gene, modulates risk for autism spectrum disorders.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CAMK4 antibody

 Reference Product  PubMed Publications
 CREBBP antibody  >6 publications with CAMK4 and CREBBP
 CREB1 antibody  >5 publications with CAMK4 and CREB1
 SRF antibody  >2 publications with CAMK4 and SRF
 MEF2D antibody  >1 publications with CAMK4 and MEF2D
 CALM1 antibody  >1 publications with CAMK4 and CALM1
 HDAC4 antibody  >1 publications with CAMK4 and HDAC4
 CABIN1 antibody  >1 publications with CAMK4 and CABIN1

Pathways associated with anti-CAMK4 antibody

 Products by Pathway  Pathway Diagram
 Activation Of CaMK IV Pathway antibodies  Activation Of CaMK IV Pathway Diagram
 Activation Of NMDA Receptor Upon Glutamate Binding And Postsynaptic Events Pathway antibodies  Activation Of NMDA Receptor Upon Glutamate Binding And Postsynaptic Events Pathway Diagram
 Alcoholism Pathway antibodies  Alcoholism Pathway Diagram
 Alcoholism Pathway antibodies  Alcoholism Pathway Diagram
 Amphetamine Addiction Pathway antibodies  Amphetamine Addiction Pathway Diagram
 Amphetamine Addiction Pathway antibodies  Amphetamine Addiction Pathway Diagram
 BDNF Signaling Pathway antibodies  BDNF Signaling Pathway Diagram
 CREB Phosphorylation Through The Activation Of CaMKK Pathway antibodies  CREB Phosphorylation Through The Activation Of CaMKK Pathway Diagram
 Ca-dependent Events Pathway antibodies  Ca-dependent Events Pathway Diagram
 CaM Pathway antibodies  CaM Pathway Diagram

Diseases associated with anti-CAMK4 antibody

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >21 publications with CAMK4 and Nervous System Diseases
 Brain Diseases Antibodies  >12 publications with CAMK4 and Brain Diseases
 Cardiovascular Diseases Antibodies  >11 publications with CAMK4 and Cardiovascular Diseases
 Mental Disorders Antibodies  >11 publications with CAMK4 and Mental Disorders
 Pain Antibodies  >9 publications with CAMK4 and Pain
 Memory Disorders Antibodies  >8 publications with CAMK4 and Memory Disorders
 Inflammation Antibodies  >7 publications with CAMK4 and Inflammation
 Learning Disorders Antibodies  >6 publications with CAMK4 and Learning Disorders
 Necrosis Antibodies  >5 publications with CAMK4 and Necrosis
 Heart Diseases Antibodies  >4 publications with CAMK4 and Heart Diseases

Organs/Tissues associated with anti-CAMK4 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >131 publications with CAMK4 and Brain
 Blood Antibodies  >40 publications with CAMK4 and Blood
 Muscle Antibodies  >21 publications with CAMK4 and Muscle
 Testis Antibodies  >12 publications with CAMK4 and Testis
 Thymus Antibodies  >10 publications with CAMK4 and Thymus
 Kidney Antibodies  >6 publications with CAMK4 and Kidney
 Spleen Antibodies  >5 publications with CAMK4 and Spleen
 Skin Antibodies  >3 publications with CAMK4 and Skin
 Liver Antibodies  >2 publications with CAMK4 and Liver
 Lymph Node Antibodies  >1 publications with CAMK4 and Lymph Node
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