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CLEC12B Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6286595

Cell surface receptor that protects target cells against natural killer cell-mediated lysis. Modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases. More details

$1060 / 0.2 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CLEC12B, Polyclonal Antibody
Full Product Name
CLEC12B, CT (CLEC12B, C-type lectin domain family 12 member B, Macrophage antigen H) (Azide free) (HRP)
Product Gene Name
Product Synonym Names
CLEC12B; C-type lectin domain family 12 member B; Macrophage antigen H
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Horseradish Peroxidase (HRP).
Purity/Purification
Purified by Protein A Affinity Chromatography.
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
26,740 Da
3D Structure
ModBase 3D Structure for Q2HXU8
Immunogen
CLEC12B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 245-276 amino acids from the C-terminal region of human CLEC12B.
Conjugate
HRP
Note
Preservative Free

Product Categories/Family for anti-CLEC12B antibody

Applications Tested/Suitable for anti-CLEC12B antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes for anti-CLEC12B antibody
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-CLEC12B antibody

Western Blot analysis of K562 cell line lysates (35ug/lane) usingMBS6008238.This demonstrates MBS6008238 detected the CLEC12B protein (arrow).
Rabbit Anti-CLEC12B Polyclonal Antibody – Cat# MBS6286595

Western Blot (WB) of anti-CLEC12B antibody

Western Blot analysis of mouse testis tissue lysates (35ug/lane) usingMBS6008238. This demonstrates MBS6008238 detected the CLEC12B protein (arrow).
Rabbit Anti-CLEC12B Polyclonal Antibody, Western Blot (WB) – Cat# MBS6286595

Immunohistochemistry (IHC) of anti-CLEC12B antibody

Immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue using MBS6008238 followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of MBS6008238 for immunohistochemistry.
Rabbit Anti-CLEC12B Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS6286595

Product References and Citations for anti-CLEC12B antibody

Hoffmann, S.C., et al. J. Biol. Chem. 282(31):22370-22375(2007). Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003).

Other Notes

Small volumes of anti-CLEC12B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CLEC12B purchase

MBS6286595 is an antibody targeting CLEC12B. Also known as CLEC12B, CT (CLEC12B, C-type lectin domain family 12 member B, Macrophage antigen H) (Azide free) (HRP). Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CLEC12B. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI Related Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
C-type lectin domain family 12 member B isoform 1
NCBI Official Synonym Full Names
C-type lectin domain family 12 member B
NCBI Official Symbol
CLEC12B
NCBI Official Synonym Symbols
UNQ5782
UniProt Protein Name
C-type lectin domain family 12 member B
UniProt Synonym Protein Names
Macrophage antigen H
UniProt Gene Name
CLEC12B
UniProt Entry Name
CL12B_HUMAN
NCBI Protein Information
C-type lectin domain family 12 member B

UniProt Comments for CLEC12B

CLEC12B: Cell surface receptor that protects target cells against natural killer cell-mediated lysis. Modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Receptor, misc.

Chromosomal Location of Human Ortholog: 12p13.2

Cellular Component: integral to membrane; plasma membrane

Molecular Function: carbohydrate binding
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Research Articles on CLEC12B

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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