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CO8G Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9513984

The protein encoded by this gene belongs to the lipocalin family. It is one of the three subunits that constitutes complement component 8 (C8), which is composed of a disulfide-linked C8 alpha-gamma heterodimer and a non-covalently associated C8 beta chain.… More details

$300 / 0.05 mL +1 FREE 8GB USB
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
CO8G, Polyclonal Antibody
Full Product Name
CO8G Rabbit Polyclonal Antibody
Product Gene Name
Product Synonym Gene Name
C8G
Product Synonym Names
BH6842; Complement component C8 gamma chain
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1mg/ml (lot specific)
Specificity
CO8G Polyclonal Antibody detects endogenous levels of protein.
Preparation and Storage
Store at -20 degree C/1 year
Molecular Weight
22,277 Da
Chromosome Location
Chromosome: 9; NC_000009.11 (139839698..139841426). Location: 9q34.3
OMIM
120930
3D Structure
ModBase 3D Structure for P07360
Immunogen
Synthesized peptide derived from part region of human protein
Modification
Unmodified/Total
Applications Tested/Suitable for anti-CO8G antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-CO8G antibody
WB: 1:500-2000
ELISA: 1:5000-20000

Western Blot (WB) of anti-CO8G antibody

Western blot analysis of lysates from KB cells, primary antibody was diluted at 1:1000, 4 degree over night
Rabbit Anti-CO8G Polyclonal Antibody – Cat# MBS9513984

Other Notes

Small volumes of anti-CO8G antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CO8G purchase

MBS9513984 is an antibody targeting CO8G. Also known as CO8G Rabbit Polyclonal Antibody. Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CO8G. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
complement component C8 gamma chain
NCBI Official Synonym Full Names
complement component 8, gamma polypeptide
NCBI Official Symbol
C8G
NCBI Official Synonym Symbols
C8C
UniProt Protein Name
Complement component C8 gamma chain
UniProt Gene Name
C8G
UniProt Entry Name
CO8G_HUMAN
NCBI Protein Information
complement component C8 gamma chain

NCBI Summary for CO8G

The protein encoded by this gene belongs to the lipocalin family. It is one of the three subunits that constitutes complement component 8 (C8), which is composed of a disulfide-linked C8 alpha-gamma heterodimer and a non-covalently associated C8 beta chain. C8 participates in the formation of the membrane attack complex (MAC) on bacterial cell membranes. While subunits alpha and beta play a role in complement-mediated bacterial killing, the gamma subunit is not required for the bactericidal activity. [provided by RefSeq, Jul 2011]
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UniProt Comments for CO8G

C8G: C8 is a constituent of the membrane attack complex. C8 binds to the C5B-7 complex, forming the C5B-8 complex. C5-B8 binds C9 and acts as a catalyst in the polymerization of C9. The gamma subunit seems to be able to bind retinol. Belongs to the calycin superfamily. Lipocalin family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 9q34.3

Cellular Component: membrane attack complex; extracellular region

Molecular Function: complement binding; protein complex binding; retinol binding

Biological Process: cytolysis; complement activation, alternative pathway; regulation of complement activation; innate immune response; complement activation, classical pathway
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-CO8G antibody

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