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COMMD3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9630678

MBS9630678 is an antibody targeting COMMD3. Also known as COMMD3 Antibody. Reactive in Human, Mouse. Host: Rabbit. More details

$325 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
COMMD3, Polyclonal Antibody
Full Product Name
COMMD3 Antibody
Product Gene Name
Product Synonym Names
BUP; C10orf8; COMM domain containing 3; COMM domain containing protein 3; DKFZp686K0399; FLJ45471; Protein Bup; Protein PIL
Clonality
Polyclonal
Isotype
Rabbit IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Concentration
1mg/ml (lot specific)
Specificity
COMMD3 Antibody detects endogenous levels of COMMD3.
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Antibody/Peptide Pairs
COMMD3 peptide (MBS9633061) is used for blocking the activity of COMMD3 antibody (MBS9630678)
Molecular Weight
22,151 Da
Chromosome Location
Chromosome: 10; NC_000010.10 (22605299..22609237). Location: 10pter-q22.1
3D Structure
ModBase 3D Structure for Q9UBI1
Supply Chain Verification
Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available, please inquire.
Immunogen
A synthesized peptide derived from human COMMD3.
Conjugation
Unconjugated
Subunit Structure
Interacts (via COMM domain) with COMMD1 (via COMM domain). Interacts with NFKB1/p105. Interacts with CCDC22, CCDC93, SCNN1B, CUL3, CUL4A, CUL4B, CUL5.
Tissue Specificity
Widely expressed with highest expression in thymus.
Function
May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. May down-regulate activation of NF-kappa-B. Modulates Na(+) transport in epithelial cells by regulation of apical cell surface expression of amiloride-sensitive sodium channel (ENaC) subunits.

Product Categories/Family for anti-COMMD3 antibody

ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-COMMD3 antibody
ELISA (EIA)(peptide)
Application Notes for anti-COMMD3 antibody
ELISA(peptide): 1:20000-1:40000

Other Notes

Small volumes of anti-COMMD3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for COMMD3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
COMM domain-containing protein 3
NCBI Official Synonym Full Names
COMM domain containing 3
NCBI Official Symbol
COMMD3
NCBI Official Synonym Symbols
BUP; C10orf8; FLJ45471; DKFZp686K0399
UniProt Protein Name
COMM domain-containing protein 3
UniProt Synonym Protein Names
Protein Bup; Protein PIL
UniProt Gene Name
COMMD3
UniProt Synonym Gene Names
BUP; C10orf8
UniProt Entry Name
COMD3_HUMAN
NCBI Protein Information
COMM domain-containing protein 3; protein Bup; OTTHUMP00000019286; OTTHUMP00000019287; OTTHUMP00000019288; OTTHUMP00000019289

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-COMMD3 antibody

Organs/Tissues associated with anti-COMMD3 antibody

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