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COX7A2L Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6288155

Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial… More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
COX7A2L, Polyclonal Antibody
Full Product Name
COX7A2L, ID (COX7A2L, COX7AR, COX7RP, Cytochrome c oxidase subunit 7A-related protein, mitochondrial, COX7a-related protein, Cytochrome c oxidase subunit VIIa-related protein, EB1) (Biotin)
Product Gene Name
anti-COX7A2L antibody
Product Synonym Names
COX7A2L; COX7AR; COX7RP; Cytochrome c oxidase subunit 7A-related protein, mitochondrial; COX7a-related protein; Cytochrome c oxidase subunit VIIa-related protein; EB1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
12,615 Da
Chromosome Location
Chromosome: 2; NC_000002.11 (42577640..42596150, complement). Location: 2p21
OMIM
605771
3D Structure
ModBase 3D Structure for O14548
Immunogen
COX7A2L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-65 amino acids from the Central region of human COX7A2L.
Conjugate
Biotin
Note
Preservative Free

Product Categories/Family for anti-COX7A2L antibody

Antibodies; Enzymes; Cytochrome
Applications Tested/Suitable for anti-COX7A2L antibody
Immunohistochemistry (IHC), ELISA (EIA), Western Blot (WB)
Application Notes for anti-COX7A2L antibody
IHC: 1:10-50
ELISA: 1:1,000
WB: 1:100-500
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-COX7A2L antibody

COX7A2L Antibody (Center) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the COX7A2L antibody detected the COX7A2L protein (arrow).
Rabbit Anti-COX7A2L Polyclonal Antibody – Cat# MBS6288155

Western Blot (WB) of anti-COX7A2L antibody

COX7A2L Antibody (Center) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the COX7A2L antibody detected the COX7A2L protein (arrow).
Rabbit Anti-COX7A2L Polyclonal Antibody, Western Blot (WB) – Cat# MBS6288155

Immunohistochemistry (IHC) of anti-COX7A2L antibody

COX7A2L Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of COX7A2L Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Rabbit Anti-COX7A2L Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS6288155

Product References and Citations for anti-COX7A2L antibody

Fornuskova, D., et al. Biochem. J. 428(3):363-374(2010). Wheeler, H.E., et al. PLoS Genet. 5 (10), E1000685 (2009): Wang, L., et al. Cancer Epidemiol. Biomarkers Prev. 17(12):3558-3566(2008). Schmidt, T.R., et al. J. Mol. Evol. 57(2):222-228(2003). Lee, N., et al. Am. J. Hum. Genet. 68(2):397-409(2001).

Other Notes

Small volumes of anti-COX7A2L antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for COX7A2L purchase

MBS6288155 is an antibody targeting COX7A2L. Also known as COX7A2L, ID (COX7A2L, COX7AR, COX7RP, Cytochrome c oxidase subunit 7A-related protein, mitochondrial, COX7a-related protein, Cytochrome c oxidase subunit VIIa-related protein, EB1) (Biotin). Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for COX7A2L. It may not necessarily be applicable to this product.

NCBI GI #
18105037
NCBI GeneID
9167
NCBI Accession #
NP_004709.2
UniProt Primary Accession #
O14548
UniProt Secondary Accession #
Q9P118
UniProt Related Accession #
O14548
GenBank Nucleotide #
NM_004718.2
NCBI Official Full Name
cytochrome c oxidase subunit 7A-related protein, mitochondrial
NCBI Official Synonym Full Names
cytochrome c oxidase subunit VIIa polypeptide 2 like
NCBI Official Symbol
COX7A2L
NCBI Official Synonym Symbols
EB1; SIG81; COX7AR; COX7RP
UniProt Protein Name
Cytochrome c oxidase subunit 7A-related protein, mitochondrial
UniProt Synonym Protein Names
COX7a-related protein; Cytochrome c oxidase subunit VIIa-related protein; EB1
Protein Family
Cytochrome c oxidase subunit 7A-related protein
UniProt Gene Name
COX7A2L
UniProt Synonym Gene Names
COX7AR; COX7RP
UniProt Entry Name
COX7R_HUMAN
NCBI Protein Information
cytochrome c oxidase subunit 7A-related protein, mitochondrial; COX7a-related protein; estrogen receptor binding CpG island; cytochrome c oxidase subunit VII-related protein; cytochrome c oxidase subunit VIIa-related protein

UniProt Comments for COX7A2L

Function: May be a regulatory subunit of cytochrome c oxidase that mediates the higher level of energy production in target cells by estrogen.

Subcellular location: Mitochondrion inner membrane

By similarity.

Induction: By estrogen.

Sequence similarities: Belongs to the cytochrome c oxidase VIIa family.
Show more

Research Articles on COX7A2L

1. Novel insights into the assembly and function of human nuclear-encoded cytochrome c oxidase subunits 7a

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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