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DRAK1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6472992

MBS6472992 is an antibody targeting DRAK1. Also known as DRAK1, NT (Serine/Threonine protein Kinase 17A, DAP Kinase-related Apoptosis-inducing Protein Kinase 1, STK17A) (FITC). Reactive in Human, Mouse. Host: Rabbit. More details

$1060 / 0.2 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
DRAK1, Polyclonal Antibody
Full Product Name
DRAK1, NT (Serine/Threonine protein Kinase 17A, DAP Kinase-related Apoptosis-inducing Protein Kinase 1, STK17A) (FITC)
Product Gene Name
anti-DRAK1 antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).
Purity/Purification
Purified by Protein A/G Affinity Chromatography.
Specificity
Recognizes human DRAK1. Species Crossreactivity: mouse.
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
46,558 Da
OMIM
604726
3D Structure
ModBase 3D Structure for Q9UEE5
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 1-30 in the N-terminal region of human DRAK1 UniProt Accession # Q9UEE5.
Conjugate
FITC
Note
Preservative Free
Special Handling
Light sensitive

Product Categories/Family for anti-DRAK1 antibody

Antibodies; Protein Kinases
Applications Tested/Suitable for anti-DRAK1 antibody
Western Blot (WB), FLISA
Application Notes for anti-DRAK1 antibody
WB: 1:100-1:500
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-DRAK1 antibody

Western Blot analysis in mouse thymus tissue lysate (35ug/lane) usingMBS625481. This demonstrates that detected the DRAK1 protein (arrow).
Rabbit Anti-DRAK1 Polyclonal Antibody – Cat# MBS6472992

Western Blot (WB) of anti-DRAK1 antibody

Western Blot analysis in SK-BR-3 cell line lysates (35ug/lane) usingMBS625481. This demonstrates that detected the DRAK1 protein (arrow).
Rabbit Anti-DRAK1 Polyclonal Antibody, Western Blot (WB) – Cat# MBS6472992

Product References and Citations for anti-DRAK1 antibody

1. Sanjo, H., et al., J. Biol. Chem. 273(44):29066-29071 (1998).

Other Notes

Small volumes of anti-DRAK1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for DRAK1. It may not necessarily be applicable to this product.

NCBI GI #
109255245
NCBI GeneID
9263
NCBI Accession #
NP_004751.2
UniProt Primary Accession #
Q9UEE5
UniProt Secondary Accession #
Q8IVC8; A4D1V6
UniProt Related Accession #
Q9UEE5
GenBank Nucleotide #
NM_004760.2
NCBI Official Full Name
serine/threonine-protein kinase 17A
NCBI Official Synonym Full Names
serine/threonine kinase 17a
NCBI Official Symbol
STK17A
NCBI Official Synonym Symbols
DRAK1
UniProt Protein Name
Serine/threonine-protein kinase 17A
UniProt Synonym Protein Names
DAP kinase-related apoptosis-inducing protein kinase 1
UniProt Gene Name
STK17A
UniProt Synonym Gene Names
DRAK1
UniProt Entry Name
ST17A_HUMAN
NCBI Protein Information
serine/threonine-protein kinase 17A; DAP kinase-related apoptosis-inducing protein kinase 1; death-associated protein kinase-related 1; serine/threonine kinase 17a (apoptosis-inducing)

NCBI Summary for DRAK1

This gene is a member of the DAP kinase-related apoptosis-inducing protein kinase family and encodes an autophosphorylated nuclear protein with a protein kinase domain. The protein has apoptosis-inducing activity. [provided by RefSeq, Jul 2008]

UniProt Comments for DRAK1

DRAK1: a calmodulin-dependent kinase of the DAPK family. Interacts with and is regulated by calcineurin homologous protein (CHP), an EF-hand Ca(2+)-binding protein. In vitro, CHP inhibits the apoptosis-inducing protein kinase DRAK2 in the presence of elevated Ca(2+) levels. Highly expressed in placenta, lung, pancreas. Lower levels in heart, brain, liver, skeletal muscle and kidney.

Protein type: Kinase, protein; Protein kinase, CAMK; EC 2.7.11.1; Protein kinase, Ser/Thr (non-receptor); CAMK group; DAPK family

Chromosomal Location of Human Ortholog: 7p13

Cellular Component: nucleus

Molecular Function: protein serine/threonine kinase activity; ATP binding

Biological Process: apoptosis; positive regulation of apoptosis; protein amino acid phosphorylation
Show more

Research Articles on DRAK1

1. STK17A provides a proliferative and survival advantage to GBM cells

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-DRAK1 antibody

 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >1 publications with DRAK1 and Nervous System Diseases
 Carcinoma, Squamous Cell Antibodies  >1 publications with DRAK1 and Carcinoma, Squamous Cell
 Pancreatic Neoplasms Antibodies  >1 publications with DRAK1 and Pancreatic Neoplasms
 Prostatic Neoplasms Antibodies  >1 publications with DRAK1 and Prostatic Neoplasms
 Uterine Cervical Neoplasms Antibodies  >1 publications with DRAK1 and Uterine Cervical Neoplasms
 Colonic Neoplasms Antibodies  >1 publications with DRAK1 and Colonic Neoplasms
 Kidney Diseases Antibodies  >1 publications with DRAK1 and Kidney Diseases
 Breast Neoplasms Antibodies  >1 publications with DRAK1 and Breast Neoplasms

Organs/Tissues associated with anti-DRAK1 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >2 publications with DRAK1 and Blood
 Kidney Antibodies  >2 publications with DRAK1 and Kidney
 Bone Marrow Antibodies  >1 publications with DRAK1 and Bone Marrow
 Prostate Antibodies  >1 publications with DRAK1 and Prostate
 Bone Antibodies  >1 publications with DRAK1 and Bone
 Spleen Antibodies  >1 publications with DRAK1 and Spleen
 Brain Antibodies  >1 publications with DRAK1 and Brain
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