• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

DUSP2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9410305

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate… More details

$325 / 0.1 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
DUSP2, Polyclonal Antibody
Full Product Name
DUSP2 Antibody
Product Gene Name
anti-DUSP2 antibody
Product Synonym Names
PAC1; PAC-1
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Purity/Purification
Antigen affinity purification.
Concentration
1.8 mg/ml (lot specific)
Specificity
The antibody detects endogenous levels of total DUSP2 protein.
Preparation and Storage
Store at -20 degree C
Molecular Weight
34,400 Da
OMIM
603068
3D Structure
ModBase 3D Structure for Q05923
Immunogen Type
Peptide
Immunogen Description
Synthetic peptide corresponding to residues near the C terminal of human dual specificity phosphatase 2
Target Name
DUSP2

Product Categories/Family for anti-DUSP2 antibody

Total protein Ab
Applications Tested/Suitable for anti-DUSP2 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-DUSP2 antibody
Western blotting: 1:200-1:1000
Immunohistochemistry: 1:25-1:100

Testing Data of anti-DUSP2 antibody

Gel: 8%SDS-PAGE Lysate: 40ug Hela cell Primary antibody: 1/300 dilution Secondary antibody dilution: 1/8000 Exposure time: 1 minute
Rabbit Anti-DUSP2 Polyclonal Antibody – Cat# MBS9410305

Immunohistochemistry (IHC) of anti-DUSP2 antibody

Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using at dilution 1/30.
Rabbit Anti-DUSP2 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS9410305

Other Notes

Small volumes of anti-DUSP2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DUSP2 purchase

MBS9410305 is an antibody targeting DUSP2. Also known as DUSP2 Antibody. Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for DUSP2. It may not necessarily be applicable to this product.

NCBI GI #
4758206
NCBI GeneID
1844
NCBI Accession #
NP_004409.1
UniProt Primary Accession #
Q05923
UniProt Secondary Accession #
Q53T45
UniProt Related Accession #
Q05923
GenBank Nucleotide #
NM_004418.3
NCBI Official Full Name
dual specificity protein phosphatase 2
NCBI Official Synonym Full Names
dual specificity phosphatase 2
NCBI Official Symbol
DUSP2
NCBI Official Synonym Symbols
PAC1; PAC-1
UniProt Protein Name
Dual specificity protein phosphatase 2
UniProt Synonym Protein Names
Dual specificity protein phosphatase PAC-1
Protein Family
Dual specificity protein phosphatase
UniProt Gene Name
DUSP2
UniProt Synonym Gene Names
PAC1
UniProt Entry Name
DUS2_HUMAN
NCBI Protein Information
dual specificity protein phosphatase 2

NCBI Summary for DUSP2

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1 and ERK2, is predominantly expressed in hematopoietic tissues, and is localized in the nucleus. [provided by RefSeq, Jul 2008]
Show more

UniProt Comments for DUSP2

Regulates mitogenic signal transduction by dephosphorylating both Thr and Tyr residues on MAP kinases ERK1 and ERK2.

Research Articles on DUSP2

1. DUSP2 is an important molecule in endometrial physiology and that hypoxia-inhibited DUSP2 expression is a critical factor for the development of endometriosis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-DUSP2 antibody

 Reference Product  PubMed Publications
 DUSP4 antibody  >6 publications with DUSP2 and DUSP4
 MAPK1 antibody  >6 publications with DUSP2 and MAPK1
 DUSP6 antibody  >4 publications with DUSP2 and DUSP6
 MAPK3 antibody  >3 publications with DUSP2 and MAPK3
 DUSP8 antibody  >2 publications with DUSP2 and DUSP8
 MAPK12 antibody  >1 publications with DUSP2 and MAPK12
 MAPK14 antibody  >1 publications with DUSP2 and MAPK14
 MAPK8 antibody  >1 publications with DUSP2 and MAPK8

Pathways associated with anti-DUSP2 antibody

 Products by Pathway  Pathway Diagram
 ARMS-mediated Activation Pathway antibodies  ARMS-mediated Activation Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 DAP12 Interactions Pathway antibodies  DAP12 Interactions Pathway Diagram
 DAP12 Signaling Pathway antibodies  DAP12 Signaling Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 Downstream Signal Transduction Pathway antibodies  Downstream Signal Transduction Pathway Diagram
 Downstream Signaling Of Activated FGFR1 Pathway antibodies  Downstream Signaling Of Activated FGFR1 Pathway Diagram
 Downstream Signaling Of Activated FGFR2 Pathway antibodies  Downstream Signaling Of Activated FGFR2 Pathway Diagram
 Downstream Signaling Of Activated FGFR3 Pathway antibodies  Downstream Signaling Of Activated FGFR3 Pathway Diagram

Diseases associated with anti-DUSP2 antibody

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >19 publications with DUSP2 and Inflammation
 Nervous System Diseases Antibodies  >9 publications with DUSP2 and Nervous System Diseases
 Hematologic Diseases Antibodies  >5 publications with DUSP2 and Hematologic Diseases
 Necrosis Antibodies  >5 publications with DUSP2 and Necrosis
 Myocardial Infarction Antibodies  >4 publications with DUSP2 and Myocardial Infarction
 Neoplasm Metastasis Antibodies  >4 publications with DUSP2 and Neoplasm Metastasis
 Disease Models, Animal Antibodies  >4 publications with DUSP2 and Disease Models, Animal
 Breast Neoplasms Antibodies  >3 publications with DUSP2 and Breast Neoplasms
 Skin Diseases Antibodies  >3 publications with DUSP2 and Skin Diseases
 Carcinoma Antibodies  >3 publications with DUSP2 and Carcinoma

Organs/Tissues associated with anti-DUSP2 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >66 publications with DUSP2 and Blood
 Brain Antibodies  >5 publications with DUSP2 and Brain
 Bone Marrow Antibodies  >5 publications with DUSP2 and Bone Marrow
 Nerve Antibodies  >4 publications with DUSP2 and Nerve
 Kidney Antibodies  >4 publications with DUSP2 and Kidney
 Ovary Antibodies  >3 publications with DUSP2 and Ovary
 Uterus Antibodies  >2 publications with DUSP2 and Uterus
 Connective Tissue Antibodies  >1 publications with DUSP2 and Connective Tissue
 Skin Antibodies  >1 publications with DUSP2 and Skin
 Liver Antibodies  >1 publications with DUSP2 and Liver
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000