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EDEM3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9514346

Quality control in the endoplasmic reticulum (ER) ensures that only properly folded proteins are retained in the cell through recognition and degradation of misfolded or unassembled proteins. EDEM3 belongs to a group of proteins that accelerate degradation of… More details

$300 / 0.05 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
EDEM3, Polyclonal Antibody
Full Product Name
EDEM3 Rabbit Polyclonal Antibody
Product Gene Name
Product Synonym Gene Name
EDEM3, C1orf22
Product Synonym Names
BH6842; ER degradation-enhancing alpha-mannosidase-like 3
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1mg/ml (lot specific)
Specificity
EDEM3 Polyclonal Antibody detects endogenous levels of protein.
Preparation and Storage
Store at -20 degree C/1 year
Molecular Weight
104,664 Da
Chromosome Location
Chromosome: 1; NC_000001.10 (184659625..184724041, complement). Location: 1q25
OMIM
610214
3D Structure
ModBase 3D Structure for Q9BZQ6
Immunogen
Synthesized peptide derived from part region of human protein
Modification
Unmodified/Total
Applications Tested/Suitable for anti-EDEM3 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-EDEM3 antibody
WB: 1:500-2000
ELISA: 1:5000-20000

Other Notes

Small volumes of anti-EDEM3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for EDEM3 purchase

MBS9514346 is an antibody targeting EDEM3. Also known as EDEM3 Rabbit Polyclonal Antibody. Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for EDEM3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
ER degradation-enhancing alpha-mannosidase-like protein 3
NCBI Official Synonym Full Names
ER degradation enhancer, mannosidase alpha-like 3
NCBI Official Symbol
EDEM3
NCBI Official Synonym Symbols
C1orf22
UniProt Protein Name
ER degradation-enhancing alpha-mannosidase-like protein 3
UniProt Synonym Protein Names
Alpha-1,2-mannosidase EDEM3
UniProt Gene Name
EDEM3
UniProt Synonym Gene Names
C1orf22
UniProt Entry Name
EDEM3_HUMAN
NCBI Protein Information
ER degradation-enhancing alpha-mannosidase-like protein 3; alpha-1,2-mannosidase EDEM3; ER degradation-enhancing alpha-mannosidase-like 3; ER degradation-enhancing -mannosidase-like protein 3

UniProt Comments for EDEM3

Function: Involved in endoplasmic reticulum-associated degradation (ERAD). Accelerates the glycoprotein ERAD by proteasomes. This process depends on mannose-trimming from the N-glycans. Seems to have alpha 1,2-mannosidase activity

By similarity.

Catalytic activity: Hydrolysis of the terminal (1->2)-linked alpha-D-mannose residues in the oligo-mannose oligosaccharide Man9(GlcNAc)2.

Subcellular location: Endoplasmic reticulum lumen

By similarity.

Domain: Contains a protease-associated domain (PA) of unknown function.

Sequence similarities: Belongs to the glycosyl hydrolase 47 family.Contains 1 PA (protease associated) domain.

Sequence caution: The sequence AAG60613.1 differs from that shown. Reason: Erroneous initiation. The sequence BAG37573.1 differs from that shown. Reason: Erroneous initiation.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-EDEM3 antibody

Organs/Tissues associated with anti-EDEM3 antibody

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