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FABP3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6475656

MBS6475656 is an antibody targeting FABP3. Also known as FABP3, NT (Fatty Acid-binding Protein, Heart, Heart-type Fatty Acid-binding Protein, H-FABP, Fatty Acid-binding Protein 3, Muscle Fatty Acid-binding Protein, M-FABP, Mammary-derived Growth Inhibitor,… More details

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Product Overview

Online Datasheet in PDF
Product Name
FABP3, Polyclonal Antibody
Full Product Name
FABP3, NT (Fatty Acid-binding Protein, Heart, Heart-type Fatty Acid-binding Protein, H-FABP, Fatty Acid-binding Protein 3, Muscle Fatty Acid-binding Protein, M-FABP, Mammary-derived Growth Inhibitor, MDGI, FABP11) (FITC)
Product Gene Name
anti-FABP3 antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).
Purity/Purification
Purified by Ammonium Sulfate Precipitation.
Specificity
Recognizes human FABP3. Species Crossreactivity: mouse.
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer.
Molecular Weight
19.1 kDa (170aa), confirmed by MALDI-TOF.
OMIM
134651
3D Structure
ModBase 3D Structure for P05413
Immunogen
Synthetic peptide selected from the C-terminal region of human FABP3 (KLH).
Conjugate
FITC
Note
Preservative Free

Product Categories/Family for anti-FABP3 antibody

Antibodies; Fatty Acid Binding Protein
Applications Tested/Suitable for anti-FABP3 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-FABP3 antibody
WB: 1:50-1:100
ELISA: 1:1,000
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-FABP3 antibody

Western blot analysis of FABP3 antibody (N-term) in mouse heart tissue lysates (35ug/lane). FABP3 (arrow) was detected using the purified Pab.
Rabbit Anti-FABP3 Polyclonal Antibody – Cat# MBS6475656

Immunohistochemistry (IHC) of anti-FABP3 antibody

Formalin-fixed and paraffin-embedded human hepatocarcinoma with FABP3 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Rabbit Anti-FABP3 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS6475656

Flow Cytometry (FC/FACS) of anti-FABP3 antibody

Flow cytometric analysis of MDA-231 cells using FABP3 Antibody (N-term)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Rabbit Anti-FABP3 Polyclonal Antibody, Flow Cytometry (FC/FACS) – Cat# MBS6475656

Western Blot (WB) of anti-FABP3 antibody

Western blot analysis of FABP3 (arrow) using rabbit polyclonal FABP3 Antibody (N-term). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the FABP3 gene.
Rabbit Anti-FABP3 Polyclonal Antibody, Western Blot (WB) – Cat# MBS6475656

Product References and Citations for anti-FABP3 antibody

1. Iwayama, Y., Am. J. Med. Genet. B Neuropsychiatr. Genet. (2009). 2. Lazary, A., Eur. J. Endocrinol. 159(2), 187-196 (2008).

Other Notes

Small volumes of anti-FABP3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for FABP3. It may not necessarily be applicable to this product.

NCBI GI #
4758328
NCBI GeneID
2170
NCBI Accession #
NP_004093
UniProt Primary Accession #
P05413
UniProt Secondary Accession #
Q5VV93; Q99957; B2RAB6
UniProt Related Accession #
P05413
GenBank Nucleotide #
NM_004102.4
NCBI Official Full Name
fatty acid-binding protein, heart isoform 2
NCBI Official Synonym Full Names
fatty acid binding protein 3
NCBI Official Symbol
FABP3
NCBI Official Synonym Symbols
MDGI; FABP11; H-FABP; M-FABP; O-FABP
UniProt Protein Name
Fatty acid-binding protein, heart
UniProt Synonym Protein Names
Fatty acid-binding protein 3; Heart-type fatty acid-binding protein; H-FABP; Mammary-derived growth inhibitor; MDGI; Muscle fatty acid-binding protein; M-FABP
Protein Family
Fatty acid-binding protein
UniProt Gene Name
FABP3
UniProt Synonym Gene Names
FABP11; MDGI; H-FABP; MDGI; M-FABP
UniProt Entry Name
FABPH_HUMAN
NCBI Protein Information
fatty acid-binding protein, heart

NCBI Summary for FABP3

The intracellular fatty acid-binding proteins (FABPs) belongs to a multigene family. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Fatty acid-binding protein 3 gene contains four exons and its function is to arrest growth of mammary epithelial cells. This gene is a candidate tumor suppressor gene for human breast cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
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UniProt Comments for FABP3

FABP3: FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

Protein type: Lipid-binding

Chromosomal Location of Human Ortholog: 1p33-p32

Cellular Component: extracellular space; sarcoplasm; cytosol

Molecular Function: protein binding; icosatetraenoic acid binding; cytoskeletal protein binding; long-chain fatty acid transporter activity

Biological Process: response to drug; negative regulation of cell proliferation; cholesterol homeostasis; regulation of fatty acid oxidation; fatty acid metabolic process; response to insulin stimulus; phospholipid homeostasis
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Research Articles on FABP3

1. our research demonstrated that high FABP3 or FABP4 expression had strong prognostic value for overall survival in non-small cell lung cancer

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-FABP3 antibody

 Reference Product  PubMed Publications
 FABP1 antibody  >17 publications with FABP3 and FABP1
 FAAH antibody  >2 publications with FABP3 and FAAH
 SIRT1 antibody  >1 publications with FABP3 and SIRT1

Pathways associated with anti-FABP3 antibody

 Products by Pathway  Pathway Diagram
 Hormone-sensitive Lipase (HSL)-mediated Triacylglycerol Hydrolysis Pathway antibodies  Hormone-sensitive Lipase (HSL)-mediated Triacylglycerol Hydrolysis Pathway Diagram
 Lipid Digestion, Mobilization, And Transport Pathway antibodies  Lipid Digestion, Mobilization, And Transport Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 PPAR Signaling Pathway antibodies  PPAR Signaling Pathway Diagram
 PPAR Signaling Pathway antibodies  PPAR Signaling Pathway Diagram

Diseases associated with anti-FABP3 antibody

 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >150 publications with FABP3 and Cardiovascular Diseases
 Heart Diseases Antibodies  >129 publications with FABP3 and Heart Diseases
 Nervous System Diseases Antibodies  >38 publications with FABP3 and Nervous System Diseases
 Fatty Liver Antibodies  >33 publications with FABP3 and Fatty Liver
 Necrosis Antibodies  >29 publications with FABP3 and Necrosis
 Heart Failure Antibodies  >24 publications with FABP3 and Heart Failure
 Inflammation Antibodies  >20 publications with FABP3 and Inflammation
 Disease Models, Animal Antibodies  >17 publications with FABP3 and Disease Models, Animal
 Breast Neoplasms Antibodies  >15 publications with FABP3 and Breast Neoplasms
 Hypertension Antibodies  >11 publications with FABP3 and Hypertension

Organs/Tissues associated with anti-FABP3 antibody

 Organ/Tissue Name  Pubmed Publications
 Heart Antibodies  >236 publications with FABP3 and Heart
 Muscle Antibodies  >111 publications with FABP3 and Muscle
 Brain Antibodies  >82 publications with FABP3 and Brain
 Liver Antibodies  >34 publications with FABP3 and Liver
 Kidney Antibodies  >22 publications with FABP3 and Kidney
 Connective Tissue Antibodies  >22 publications with FABP3 and Connective Tissue
 Embryonic Tissue Antibodies  >13 publications with FABP3 and Embryonic Tissue
 Lung Antibodies  >12 publications with FABP3 and Lung
 Placenta Antibodies  >8 publications with FABP3 and Placenta
 Bone Antibodies  >5 publications with FABP3 and Bone
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