• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

FCGR2C Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6475763

MBS6475763 is an antibody targeting FCGR2C. Also known as FCGR2C, CT (CD32, CDw32, Fc-gamma RII-c, Fc-gamma-RIIc, FcRII-c, Low Affinity Immunoglobulin gamma Fc Region Receptor II-c, IgG Fc Receptor II-c, CD32, FCG2, IGFR2) (MaxLight 750). Reactive in Human,… More details

$1025 / 0.1 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
FCGR2C, Polyclonal Antibody
Full Product Name
FCGR2C, CT (CD32, CDw32, Fc-gamma RII-c, Fc-gamma-RIIc, FcRII-c, Low Affinity Immunoglobulin gamma Fc Region Receptor II-c, IgG Fc Receptor II-c, CD32, FCG2, IGFR2) (MaxLight 750)
Product Gene Name
anti-FCGR2C antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight750.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Specificity
Recognizes human FCGR2C. Species Crossreactivity: mouse
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight750 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
35.578
OMIM
612169
3D Structure
ModBase 3D Structure for P31995
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 281-307 in the C-terminal region of human FCGR2C, UniProt Accession #NP_001005410.2; P31995; P12318.
Conjugate
MaxLight750
Note
Preservative Free

Product Categories/Family for anti-FCGR2C antibody

Antibodies; Receptors
Applications Tested/Suitable for anti-FCGR2C antibody
Western Blot (WB), FLISA, Immunohistochemistry (IHC)
Application Notes for anti-FCGR2C antibody
WB: 1:100-1:500
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-FCGR2C antibody

Western Blot analysis in mouse brain tissue lysates (35ug/lane) usingMBS631339. FCGR2C (arrow) was detected usingF0025-92.
Rabbit Anti-FCGR2C Polyclonal Antibody – Cat# MBS6475763

Immunohistochemistry (IHC) of anti-FCGR2C antibody

Immunohistochemistry analysis in formalin-fixed and paraffin-embedded human lung carcinoma usingMBS631339, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of MBS631339 for immunohistochemistry.
Rabbit Anti-FCGR2C Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS6475763

Product References and Citations for anti-FCGR2C antibody

1. Metes D., et.al., Blood 91:2369-2380(1998). 2. Stuart S.G., et.al., EMBO J. 8:3657-3666(1989).

Other Notes

Small volumes of anti-FCGR2C antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for FCGR2C. It may not necessarily be applicable to this product.

NCBI GI #
126116583
NCBI Accession #
NP_001005410.2
UniProt Primary Accession #
P31995
UniProt Secondary Accession #
P12318
UniProt Protein Name
Low affinity immunoglobulin gamma Fc region receptor II-c
UniProt Synonym Protein Names
CDw32; Fc-gamma RII-c
Protein Family
Low affinity immunoglobulin gamma Fc region receptor
UniProt Gene Name
FCGR2C
UniProt Synonym Gene Names
CD32; FCG2; IGFR2; IgG Fc receptor II-c; Fc-gamma-RIIc; FcRII-c
UniProt Entry Name
FCG2C_HUMAN

UniProt Comments for FCGR2C

FCGR2C: a transmembrane receptor for the Fc region of complexed or aggregated immunoglobulin gamma (IgG). Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down modulation of previous state of cell activation triggered via antigen receptors on B cells, T cells or via another Fc receptor. Three splice-variant isoforms have been observed.

Protein type: Immunoglobulin superfamily; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1q23.3

Cellular Component: cytoplasm; plasma membrane; integral to membrane

Molecular Function: protein binding; transmembrane receptor activity; IgG binding

Biological Process: immune response; signal transduction

Disease: Thrombocytopenic Purpura, Autoimmune
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000