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FKBP11 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6476067

MBS6476067 is an antibody targeting FKBP11. Also known as FKBP11, NT (FK506-binding Protein 11, Peptidyl-prolyl cis-trans Isomerase FKBP11, PPIase FKBP11, Rotamase, 19kD FK506-binding Protein, 19kD FKBP, FKBP-19, UNQ336/PRO535, FKBP19, FKBP-11) (APC).… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
FKBP11, Polyclonal Antibody
Full Product Name
FKBP11, NT (FK506-binding Protein 11, Peptidyl-prolyl cis-trans Isomerase FKBP11, PPIase FKBP11, Rotamase, 19kD FK506-binding Protein, 19kD FKBP, FKBP-19, UNQ336/PRO535, FKBP19, FKBP-11) (APC)
Product Gene Name
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
Purity/Purification
Purified by Ammonium Sulfate Precipitation.
Specificity
Recognizes human FKBP11. Species Crossreactivity: mouse.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
19kDa
OMIM
610571
3D Structure
ModBase 3D Structure for Q9NYL4
Immunogen
Synthetic peptide selected from the N-terminal region of human FKBP11 (KLH).
Conjugate
APC
Note
Preservative Free

Product Categories/Family for anti-FKBP11 antibody

Applications Tested/Suitable for anti-FKBP11 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-FKBP11 antibody
WB: 1:50-1:100
ELISA: 1:1,000
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-FKBP11 antibody

Western blot analysis of FKBP11 Antibody (N-term) in mouse stomach tissue lysates (35ug/lane). FKBP11 (arrow) was detected using the purified Pab.
Rabbit Anti-FKBP11 Polyclonal Antibody – Cat# MBS6476067

Immunohistochemistry (IHC) of anti-FKBP11 antibody

FKBP11 Antibody (N-term) IHC analysis in formalin fixed and paraffin embedded human tonsil tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the FKBP11 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Rabbit Anti-FKBP11 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS6476067

Flow Cytometry (FC/FACS) of anti-FKBP11 antibody

FKBP11 Antibody (N-term) flow cytometric analysis of HL-60 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Rabbit Anti-FKBP11 Polyclonal Antibody, Flow Cytometry (FC/FACS) – Cat# MBS6476067

Product References and Citations for anti-FKBP11 antibody

1. Rulten, S.L., et.al., Mamm. Genome 17(4), 322-331 (2006).

Other Notes

Small volumes of anti-FKBP11 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for FKBP11. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
peptidyl-prolyl cis-trans isomerase FKBP11 isoform 1
NCBI Official Synonym Full Names
FKBP prolyl isomerase 11
NCBI Official Symbol
FKBP11
NCBI Official Synonym Symbols
FKBP19
UniProt Protein Name
Peptidyl-prolyl cis-trans isomerase FKBP11
UniProt Synonym Protein Names
19 kDa FK506-binding protein; 19 kDa FKBP; FKBP-19; FK506-binding protein 11; FKBP-11; Rotamase
UniProt Gene Name
FKBP11
UniProt Synonym Gene Names
FKBP19; PPIase FKBP11; 19 kDa FKBP; FKBP-19; FKBP-11
UniProt Entry Name
FKB11_HUMAN
NCBI Protein Information
peptidyl-prolyl cis-trans isomerase FKBP11

NCBI Summary for FKBP11

FKBP11 belongs to the FKBP family of peptidyl-prolyl cis/trans isomerases, which catalyze the folding of proline-containing polypeptides. The peptidyl-prolyl isomerase activity of FKBP proteins is inhibited by the immunosuppressant compounds FK506 and rapamycin (Rulten et al., 2006 [PubMed 16596453]).[supplied by OMIM, Mar 2008]
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UniProt Comments for FKBP11

FKBP11: PPIases accelerate the folding of proteins during protein synthesis. Belongs to the FKBP-type PPIase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Isomerase; EC 5.2.1.8

Chromosomal Location of Human Ortholog: 12q13.12

Cellular Component: endoplasmic reticulum membrane; membrane; integral to membrane

Molecular Function: peptidyl-prolyl cis-trans isomerase activity; FK506 binding

Biological Process: protein peptidyl-prolyl isomerization
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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