Rabbit Anti-NRG1 Polyclonal Antibody – Cat# MBS125466

Western blot analysis of extracts of SK-BR-3 cells, using NRG1 antibody.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.

Heregulin NRG1 (NRG1) Antibody – Rabbit Polyclonal

Name: NRG1 Antibody; Polyclonal; Rabbit; Human/Mouse-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS125466
Price: 360 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS125466

Rabbit polyclonal to NRG1Heregulin (HRG), also called neuregulin (NRG1), neu differentiation factor (NDF) or glial growth factor-2 (GGF-2), is a soluble growth factor synthesized as a transmembrane precursor molecule. Metalloproteinases and other proteases… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

Heregulin NRG1, Polyclonal Antibody

Full Product Name

NRG1 Rabbit pab Antibody

Product Gene Name

anti-NRG1 antibody

Product Synonym Names

NRG1; Heregulin NRG1; Heregulin NRG1; NRG1; ARIA; GGF; GGF2; HGL; HRG; HRG1; HRGA; NDF; SMDF;

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human, mouse

Form/Format

Liquid

Purity/Purification

Affinity purification

Preparation and Storage

Upon delivery aliquot and store at -20 degree C or -80 degree C.

Molecular Weight

640

Chromosome Location

Chromosome: 8; NC_000008.10 (31496820..32622558). Location: 8p12

OMIM

142445

3D Structure

ModBase 3D Structure for Q02297

Immunogen

A synthetic -peptide of human NRG1

Buffer

PBS with 0.1% Sodium Azide, 50% Glycerol,

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for anti-NRG1 antibody

Western Blot (WB), Immunohistochemistry (IHC)

Application Notes for anti-NRG1 antibody

Western Blot (WB): 1/500-1000
Immunohistochemistry (IHC): 1/50-100

Product References and Citations for anti-NRG1 antibody

1. Breuleux, M. (2007) Cell Mol Life Sci 64, 2358-77. 2. Ozaki, M. et al. (2004) J Neurochem 91, 176-88. 3. Falls, D.L. (2003) Exp Cell Res 284, 14-30.

Other Notes

Small volumes of anti-NRG1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NRG1 purchase

MBS125466 is an antibody targeting NRG1. Also known as NRG1 Rabbit pab Antibody. Reactive in Human, mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for NRG1. It may not necessarily be applicable to this product.

NCBI GI #

236461509

NCBI GeneID

3084

NCBI Accession #

NP_001153467.1

UniProt Primary Accession #

Q02297

UniProt Secondary Accession #

O14667; P98202; Q02298; Q02299; Q07110; Q07111; A5YAK4; A5YAK5; A8K1L2; B7Z4Z3; E9PHH4

UniProt Related Accession #

Q02297

GenBank Nucleotide #

NM_001159995.1

NCBI Official Full Name

pro-neuregulin-1, membrane-bound isoform isoform HRG-beta1c

NCBI Official Synonym Full Names

neuregulin 1

NCBI Official Symbol

NRG1

NCBI Official Synonym Symbols

GGF; HGL; HRG; NDF; ARIA; GGF2; HRG1; HRGA; SMDF; MST131

UniProt Protein Name

Pro-neuregulin-1, membrane-bound isoform

UniProt Synonym Protein Names

Acetylcholine receptor-inducing activity; ARIA; Breast cancer cell differentiation factor p45; Glial growth factor; Heregulin; HRG; Neu differentiation factor; Sensory and motor neuron-derived factor

Protein Family

Pro-neuregulin

UniProt Gene Name

NRG1

UniProt Synonym Gene Names

GGF; HGL; HRGA; NDF; SMDF; Pro-NRG1; ARIA; HRG

UniProt Entry Name

NRG1_HUMAN

NCBI Protein Information

pro-neuregulin-1, membrane-bound isoform; MSTP131; pro-NRG1; glial growth factor; neu differentiation factor; neuregulin 1 type IV beta 3; neuregulin 1 type IV beta 1a; sensory and motor neuron derived factor; heregulin, alpha (45kD, ERBB2 p185-activator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-NRG1 antibody

Products by Pathway	Pathway Diagram
Adaptive Immune System Pathway antibodies	Adaptive Immune System Pathway Diagram
Cardiac Progenitor Differentiation Pathway antibodies	Cardiac Progenitor Differentiation Pathway Diagram
Constitutive PI3K/AKT Signaling In Cancer Pathway antibodies	Constitutive PI3K/AKT Signaling In Cancer Pathway Diagram
DAP12 Interactions Pathway antibodies	DAP12 Interactions Pathway Diagram
DAP12 Signaling Pathway antibodies	DAP12 Signaling Pathway Diagram
Disease Pathway antibodies	Disease Pathway Diagram
Downregulation Of ERBB2:ERBB3 Signaling Pathway antibodies	Downregulation Of ERBB2:ERBB3 Signaling Pathway Diagram
Downstream Signaling Events Of B Cell Receptor (BCR) Pathway antibodies	Downstream Signaling Events Of B Cell Receptor (BCR) Pathway Diagram
Downstream Signal Transduction Pathway antibodies	Downstream Signal Transduction Pathway Diagram
Downstream Signaling Of Activated FGFR Pathway antibodies	Downstream Signaling Of Activated FGFR Pathway Diagram

Diseases associated with anti-NRG1 antibody

Disease Name	Pubmed Publications
Schizophrenia Antibodies	>347 publications with NRG1 and Schizophrenia
Nervous System Diseases Antibodies	>97 publications with NRG1 and Nervous System Diseases
Neoplasms Antibodies	>76 publications with NRG1 and Neoplasms
Breast Neoplasms Antibodies	>33 publications with NRG1 and Breast Neoplasms
Cardiovascular Diseases Antibodies	>29 publications with NRG1 and Cardiovascular Diseases
Heart Diseases Antibodies	>22 publications with NRG1 and Heart Diseases
Carcinoma Antibodies	>21 publications with NRG1 and Carcinoma
Cognition Disorders Antibodies	>21 publications with NRG1 and Cognition Disorders
Nerve Degeneration Antibodies	>14 publications with NRG1 and Nerve Degeneration
Drug Toxicity Antibodies	>12 publications with NRG1 and Drug Toxicity

Organs/Tissues associated with anti-NRG1 antibody

Organ/Tissue Name	Pubmed Publications
Nerve Antibodies	>295 publications with NRG1 and Nerve
Brain Antibodies	>291 publications with NRG1 and Brain
Bone Antibodies	>14 publications with NRG1 and Bone
Eye Antibodies	>8 publications with NRG1 and Eye
Liver Antibodies	>7 publications with NRG1 and Liver
Skin Antibodies	>7 publications with NRG1 and Skin
Kidney Antibodies	>6 publications with NRG1 and Kidney
Intestine Antibodies	>5 publications with NRG1 and Intestine