• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

IPO11 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2560764

Importins, including IPO11, are a members of the karyopherin/importin-beta family of transport receptors (see KPNB1; 602738) that mediate nucleocytoplasmic transport of protein and RNA cargoes (Plafker and Macara, 2000 [PubMed 11032817]). More details

$160 / 0.02 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
IPO11, Polyclonal Antibody
Full Product Name
IPO11 Polyclonal Antibody
Product Gene Name
anti-IPO11 antibody
Product Synonym Names
Imp11; Importin 11; Importin-11; IPO11; IPO11; Ran binding protein 11; Ran-binding protein 11; RanBP11; SLRN; Synleurin
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purity/Purification
Antigen Affinity Purification
Concentration
1.2mg/mL (lot specific)
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
Molecular Weight
113 kDa
OMIM
610889
3D Structure
ModBase 3D Structure for Q9UI26
Immunogen
Fusion protein of human IPO11
Conjugation
Unconjugated

Product Categories/Family for anti-IPO11 antibody

Signal Transduction
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-IPO11 antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes for anti-IPO11 antibody
WB: 1:500-1:2000
IHC: 1:50-1:300
ELISA: 1:5000-1:10000

Western Blot (WB) of anti-IPO11 antibody

Western blot analysis of K562 cell Human fetal brain tissue lysates using IPO11 Polyclonal Antibody at dilution of 1:500
Rabbit Anti-IPO11 Polyclonal Antibody – Cat# MBS2560764

Immunohistochemistry (IHC) of anti-IPO11 antibody

Immunohistochemistry of paraffin-embedded Human tonsil tissue using IPO11 Polyclonal Antibody at dilution of 1:70(×200)
Rabbit Anti-IPO11 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2560764

Immunohistochemistry (IHC) of anti-IPO11 antibody

Immunohistochemistry of paraffin-embedded Human breast cancer tissue using IPO11 Polyclonal Antibody at dilution of 1:70(×200)
Rabbit Anti-IPO11 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS2560764

Other Notes

Small volumes of anti-IPO11 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IPO11 purchase

MBS2560764 is an antibody targeting IPO11. Also known as IPO11 Polyclonal Antibody. Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for IPO11. It may not necessarily be applicable to this product.

NCBI GI #
21707128
NCBI GeneID
51194
NCBI Accession #
AAH33776.1
NCBI Related Accession #
BC033776
UniProt Primary Accession #
Q9UI26
UniProt Related Accession #
Q9UI26
NCBI Official Full Name
Importin 11
NCBI Official Synonym Full Names
importin 11
NCBI Official Symbol
IPO11
NCBI Official Synonym Symbols
RanBP11
UniProt Protein Name
Importin-11
UniProt Synonym Protein Names
Ran-binding protein 11
Protein Family
Importin
UniProt Gene Name
IPO11
UniProt Synonym Gene Names
RANBP11; Imp11; RanBP11
UniProt Entry Name
IPO11_HUMAN
NCBI Protein Information
importin-11

UniProt Comments for IPO11

IPO11: Functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran- dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. Mediates the nuclear import of UBE2E3, and of RPL12. Belongs to the importin beta family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Karyopherin; Nuclear import

Chromosomal Location of Human Ortholog: 5q12.1

Cellular Component: cytoplasm; nucleus

Molecular Function: Ran GTPase binding; protein transporter activity

Biological Process: ribosomal protein import into nucleus
Show more

Research Articles on IPO11

1. High IPO11 expression is associated with migration, invasion, and progression of bladder cancer.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-IPO11 antibody

 Reference Product  PubMed Publications
 UBE2E2 antibody  >1 publications with IPO11 and UBE2E2
 UBE2E1 antibody  >1 publications with IPO11 and UBE2E1

Organs/Tissues associated with anti-IPO11 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >2 publications with IPO11 and Brain
 Testis Antibodies  >2 publications with IPO11 and Testis
 Blood Antibodies  >1 publications with IPO11 and Blood
 Kidney Antibodies  >1 publications with IPO11 and Kidney
 Uterus Antibodies  >1 publications with IPO11 and Uterus
 Spleen Antibodies  >1 publications with IPO11 and Spleen
 Muscle Antibodies  >1 publications with IPO11 and Muscle
 Pancreas Antibodies  >1 publications with IPO11 and Pancreas
 Liver Antibodies  >1 publications with IPO11 and Liver
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000