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KLC3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6313877

KLC3 encodes a member of the kinesin light chain gene family. Kinesins are molecular motors involved in the transport of cargo along microtubules, and are composed of two kinesin heavy chain (KHC) and two kinesin light chain (KLC) molecules. KLCs are thought… More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
KLC3, Polyclonal Antibody
Full Product Name
KLC3, ID (KLC3, KLC2, KLC2L, Kinesin light chain 3, KLC2-like, kinesin light chain 2) (Biotin)
Product Gene Name
anti-KLC3 antibody
Product Synonym Names
KLC3; KLC2; KLC2L; Kinesin light chain 3; KLC2-like; kinesin light chain 2
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
56,793 Da
OMIM
601334
3D Structure
ModBase 3D Structure for Q6P597
Immunogen
KLC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 253-283 amino acids from the Central region of human KLC3.
Conjugate
Biotin
Note
Preservative Free

Product Categories/Family for anti-KLC3 antibody

Antibodies; Spermatogenesis; Testis Proteins
Applications Tested/Suitable for anti-KLC3 antibody
Flow Cytometry (FC/FACS), ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)
Application Notes for anti-KLC3 antibody
FC/FACS: 1:10-50
ELISA: 1:1,000
IHC: 1:50-100
WB: 1:100-500
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-KLC3 antibody

KLC3 Antibody (Center) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the KLC3 antibody detected the KLC3 protein (arrow).
Rabbit Anti-KLC3 Polyclonal Antibody – Cat# MBS6313877

Immunohistochemistry (IHC) of anti-KLC3 antibody

KLC3 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human colon carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the KLC3 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Rabbit Anti-KLC3 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS6313877

Flow Cytometry (FC/FACS) of anti-KLC3 antibody

KLC3 Antibody (Center) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Rabbit Anti-KLC3 Polyclonal Antibody, Flow Cytometry (FC/FACS) – Cat# MBS6313877

Product References and Citations for anti-KLC3 antibody

Zhang, Y., et al. Dev. Biol. 275(1):23-33(2004). Bhullar, B., et al. J. Biol. Chem. 278(18):16159-16168(2003). Junco, A., et al. Biol. Reprod. 64(5):1320-1330(2001).

Other Notes

Small volumes of anti-KLC3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for KLC3 purchase

MBS6313877 is an antibody targeting KLC3. Also known as KLC3, ID (KLC3, KLC2, KLC2L, Kinesin light chain 3, KLC2-like, kinesin light chain 2) (Biotin). Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for KLC3. It may not necessarily be applicable to this product.

NCBI GI #
91825557
NCBI GeneID
147700
NCBI Accession #
NP_803136.2
UniProt Primary Accession #
Q6P597
UniProt Secondary Accession #
Q6GMU2; Q8NAL1; Q8WWJ9; A0AVM3; A2RUT6
UniProt Related Accession #
Q6P597
GenBank Nucleotide #
NM_177417.2
NCBI Official Full Name
kinesin light chain 3
NCBI Official Synonym Full Names
kinesin light chain 3
NCBI Official Symbol
KLC3
NCBI Official Synonym Symbols
KLC2; KLCt; KLC2L; KNS2B
UniProt Protein Name
Kinesin light chain 3
UniProt Synonym Protein Names
KLC2-like; kinesin light chain 2
Protein Family
Kinesin
UniProt Gene Name
KLC3
UniProt Synonym Gene Names
KLC2; KLC2L
UniProt Entry Name
KLC3_HUMAN
NCBI Protein Information
kinesin light chain 3; kinesin light chain 2

NCBI Summary for KLC3

This gene encodes a member of the kinesin light chain gene family. Kinesins are molecular motors involved in the transport of cargo along microtubules, and are composed of two kinesin heavy chain (KHC) and two kinesin light chain (KLC) molecules. KLCs are thought to typically be involved in binding cargo and regulating kinesin activity. In the rat, a protein similar to this gene product is expressed in post-meiotic spermatids, where it associates with structural components of sperm tails and mitochondria. [provided by RefSeq, Jul 2008]
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Research Articles on KLC3

1. Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-KLC3 antibody

 Reference Product  PubMed Publications
 KIF5C antibody  >1 publications with KLC3 and KIF5C
 KIF5A antibody  >1 publications with KLC3 and KIF5A
 KIF5B antibody  >1 publications with KLC3 and KIF5B

Pathways associated with anti-KLC3 antibody

 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Factors Involved In Megakaryocyte Development And Platelet Production Pathway antibodies  Factors Involved In Megakaryocyte Development And Platelet Production Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Kinesins Pathway antibodies  Kinesins Pathway Diagram
 MHC Class II Antigen Presentation Pathway antibodies  MHC Class II Antigen Presentation Pathway Diagram
 Salmonella Infection Pathway antibodies  Salmonella Infection Pathway Diagram
 Salmonella Infection Pathway antibodies  Salmonella Infection Pathway Diagram

Organs/Tissues associated with anti-KLC3 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >1 publications with KLC3 and Brain
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