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KLF2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6313953

KLF2 binds to the CACCC box in the beta-globin gene promoter and activates transcription (By similarity). More details

$1060 / 0.2 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
KLF2, Polyclonal Antibody
Full Product Name
KLF2, NT (KLF2, LKLF, Krueppel-like factor 2, Lung krueppel-like factor) (APC)
Product Gene Name
Product Synonym Names
KLF2; LKLF; Krueppel-like factor 2; Lung krueppel-like factor
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
Purity/Purification
Purified by Protein A Affinity Chromatography.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
37,420 Da
OMIM
AF123344 Genomic DNA
3D Structure
ModBase 3D Structure for Q9Y5W3
Immunogen
KLF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 12-42 amino acids from the N-terminal region of human KLF2.
Conjugate
APC
Note
Preservative Free
Special Handling
Light sensitive
Applications Tested/Suitable for anti-KLF2 antibody
Western Blot (WB), FLISA
Application Notes for anti-KLF2 antibody
WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-KLF2 antibody

KLF2 Antibody (N-term) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the KLF2 antibody detected the KLF2 protein (arrow).
Rabbit Anti-KLF2 Polyclonal Antibody – Cat# MBS6313953

Western Blot (WB) of anti-KLF2 antibody

KLF2 Antibody (N-term) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the KLF2 antibody detected the KLF2 protein (arrow).
Rabbit Anti-KLF2 Polyclonal Antibody, Western Blot (WB) – Cat# MBS6313953

Product References and Citations for anti-KLF2 antibody

Lin, Z., et al. Arterioscler. Thromb. Vasc. Biol. 30(10):1952-1959(2010). Zahlten, J., et al. J. Immunol. 185(1):597-604(2010). Wang, W., et al. Blood 115(14):2971-2979(2010). Boon, R.A., et al. Blood 115(12):2533-2542(2010). Villarreal, G. Jr., et al. Biochem. Biophys. Res. Commun. 391(1):984-989(2010).

Other Notes

Small volumes of anti-KLF2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for KLF2 purchase

MBS6313953 is an antibody targeting KLF2. Also known as KLF2, NT (KLF2, LKLF, Krueppel-like factor 2, Lung krueppel-like factor) (APC). Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for KLF2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
Krueppel-like factor 2
NCBI Official Synonym Full Names
Kruppel-like factor 2
NCBI Official Symbol
KLF2
NCBI Official Synonym Symbols
LKLF
UniProt Protein Name
Krueppel-like factor 2
UniProt Synonym Protein Names
Lung krueppel-like factor
Protein Family
UniProt Gene Name
KLF2
UniProt Synonym Gene Names
LKLF
NCBI Protein Information
Krueppel-like factor 2

NCBI Summary for KLF2

Kruppel-like factors (KLFs) are a family of broadly expressed zinc finger transcription factors. KLF2 regulates T-cell trafficking by promoting expression of the lipid-binding receptor S1P1 (S1PR1; MIM 601974) and the selectin CD62L (SELL; MIM 153240) (summary by Weinreich et al., 2009 [PubMed 19592277]).[supplied by OMIM, Feb 2011]
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UniProt Comments for KLF2

Transcription factor that binds to the CACCC box in the promoter of target genes such as HBB/beta globin or NOV and activates their transcription.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-KLF2 antibody

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