• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

LSM1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9609071

Function: Plays a role in the degradation of histone mRNAs, the only eukaryotic mRNAs that are not polyadenylated (PubMed:18172165). Probably also part of an LSm subunits-containing complex involved in the general process of mRNA degradation (By… More details

$325 / 0.1 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
LSM1, Polyclonal Antibody
Full Product Name
LSM1 Antibody
Product Gene Name
anti-LSM1 antibody
Product Synonym Names
Cancer associated Sm like protein; Cancer associated Sm-like; Cancer-associated Sm-like; CASM; lsm1; LSM1 antibody; LSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae); Lsm1 protein; LSM1, U6 small nuclear RNA associated; LSM1_HUMAN; Small nuclear ribonuclear CaSm; U6 snRNA associated Sm-like protein LSm1; U6 snRNA-associated Sm-like protein LSm1; YJL124C
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Concentration
1mg/ml (lot specific)
Specificity
LSM1 antibody detects endogenous levels of total LSM1
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Antibody/Peptide Pairs
LSM1 peptide (MBS9627783) is used for blocking the activity of LSM1 antibody (MBS9609071)
Molecular Weight
Observed: 15 kDa
Predicted: 16 kDa
3D Structure
ModBase 3D Structure for O15116
Supply Chain Verification
Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available, please inquire.
Immunogen
A synthesized peptide derived from human LSM1
Subcellular Location
Nucleus.
Conjugation
Unconjugated
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-LSM1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-LSM1 antibody
WB: 1:1000-3000

Western Blot (WB) of anti-LSM1 antibody

Western blot analysis of LSM1 using Jurkat whole cell lysates
Rabbit Anti-LSM1 Polyclonal Antibody – Cat# MBS9609071

Other Notes

Small volumes of anti-LSM1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LSM1 purchase

MBS9609071 is an antibody targeting LSM1. Also known as LSM1 Antibody. Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for LSM1. It may not necessarily be applicable to this product.

NCBI GI #
7657313
NCBI GeneID
27257
NCBI Accession #
NP_055277.1
UniProt Primary Accession #
O15116
UniProt Secondary Accession #
B2R5E6
UniProt Related Accession #
O15116
GenBank Nucleotide #
NM_014462.2
NCBI Official Full Name
U6 snRNA-associated Sm-like protein LSm1
NCBI Official Synonym Full Names
LSM1 homolog, mRNA degradation associated
NCBI Official Symbol
LSM1
NCBI Official Synonym Symbols
CASM; YJL124C
UniProt Protein Name
U6 snRNA-associated Sm-like protein LSm1
UniProt Synonym Protein Names
Cancer-associated Sm-like; Small nuclear ribonuclear CaSm
Protein Family
Probable U6 snRNA-associated Sm-like protein
UniProt Gene Name
LSM1
UniProt Synonym Gene Names
CASM
NCBI Protein Information
U6 snRNA-associated Sm-like protein LSm1

NCBI Summary for LSM1

This gene encodes a member of the LSm family of RNA-binding proteins. LSm proteins form stable heteromers that bind specifically to the 3'-terminal oligo(U) tract of U6 snRNA and may play a role in pre-mRNA splicing by mediating U4/U6 snRNP formation. Increased expression of this gene may play a role in cellular transformation and the progression of several malignancies including lung cancer, mesothelioma and breast cancer. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9. [provided by RefSeq, Nov 2011]
Show more

UniProt Comments for LSM1

Plays a role in the degradation of histone mRNAs, the only eukaryotic mRNAs that are not polyadenylated (PubMed:18172165). Probably also part of an LSm subunits-containing complex involved in the general process of mRNA degradation ().

Research Articles on LSM1

1. These results provide evidence that LSm1 binding to the DENV RNA 3' UTR positively regulates DENV RNA replication.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-LSM1 antibody

 Reference Product  PubMed Publications
 LSM2 antibody  >20 publications with LSM1 and LSM2
 LSM7 antibody  >10 publications with LSM1 and LSM7
 LSM4 antibody  >7 publications with LSM1 and LSM4
 LSM3 antibody  >5 publications with LSM1 and LSM3
 LSM6 antibody  >3 publications with LSM1 and LSM6
 LSM5 antibody  >2 publications with LSM1 and LSM5
 UPF2 antibody  >1 publications with LSM1 and UPF2

Pathways associated with anti-LSM1 antibody

 Products by Pathway  Pathway Diagram
 Deadenylation-dependent MRNA Decay Pathway antibodies  Deadenylation-dependent MRNA Decay Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Lsm 1-7 Complex Pathway antibodies  Lsm 1-7 Complex Pathway Diagram
 Lsm 1-7 Complex Pathway antibodies  Lsm 1-7 Complex Pathway Diagram
 RNA Degradation Pathway antibodies  RNA Degradation Pathway Diagram
 RNA Degradation Pathway antibodies  RNA Degradation Pathway Diagram
 MRNA Decay By 5' To 3' Exoribonuclease Pathway antibodies  MRNA Decay By 5' To 3' Exoribonuclease Pathway Diagram

Diseases associated with anti-LSM1 antibody

 Disease Name  Pubmed Publications
 Fibrosis Antibodies  >3 publications with LSM1 and Fibrosis
 Disease Models, Animal Antibodies  >2 publications with LSM1 and Disease Models, Animal
 Liver Neoplasms Antibodies  >2 publications with LSM1 and Liver Neoplasms
 Infertility, Male Antibodies  >1 publications with LSM1 and Infertility, Male
 Nervous System Diseases Antibodies  >1 publications with LSM1 and Nervous System Diseases
 Adenoma, Liver Cell Antibodies  >1 publications with LSM1 and Adenoma, Liver Cell
 Neoplasms, Experimental Antibodies  >1 publications with LSM1 and Neoplasms, Experimental

Organs/Tissues associated with anti-LSM1 antibody

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >6 publications with LSM1 and Liver
 Blood Antibodies  >3 publications with LSM1 and Blood
 Prostate Antibodies  >2 publications with LSM1 and Prostate
 Brain Antibodies  >2 publications with LSM1 and Brain
 Kidney Antibodies  >1 publications with LSM1 and Kidney
 Eye Antibodies  >1 publications with LSM1 and Eye
 Skin Antibodies  >1 publications with LSM1 and Skin
 Pancreas Antibodies  >1 publications with LSM1 and Pancreas
 Lung Antibodies  >1 publications with LSM1 and Lung
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000