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LSM4 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6317485

MBS6317485 is an antibody targeting LSM4. Also known as LSM4, ID (LSM4, U6 snRNA-associated Sm-like protein LSm4, Glycine-rich protein) (Biotin). Reactive in Human, Mouse. Host: Rabbit. More details

$1060 / 0.2 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
LSM4, Polyclonal Antibody
Full Product Name
LSM4, ID (LSM4, U6 snRNA-associated Sm-like protein LSm4, Glycine-rich protein) (Biotin)
Product Gene Name
anti-LSM4 antibody
Product Synonym Names
LSM4; U6 snRNA-associated Sm-like protein LSm4; Glycine-rich protein
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
15,350 Da
OMIM
607284
3D Structure
ModBase 3D Structure for Q9Y4Z0
Immunogen
LSM4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 54-82 amino acids from the Central region of human LSM4.
Conjugate
Biotin
Note
Preservative Free

Product Categories/Family for anti-LSM4 antibody

Antibodies; Amino Acids
Applications Tested/Suitable for anti-LSM4 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-LSM4 antibody
WB: 1:100-500
ELISA: 1:1,000
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-LSM4 antibody

LSM4 Antibody (Center) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the LSM4 antibody detected the LSM4 protein (arrow).
Rabbit Anti-LSM4 Polyclonal Antibody – Cat# MBS6317485

Western Blot (WB) of anti-LSM4 antibody

LSM4 Antibody (Center) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the LSM4 antibody detected the LSM4 protein (arrow).
Rabbit Anti-LSM4 Polyclonal Antibody, Western Blot (WB) – Cat# MBS6317485

Other Notes

Small volumes of anti-LSM4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for LSM4. It may not necessarily be applicable to this product.

NCBI GI #
6912486
NCBI GeneID
25804
NCBI Accession #
NP_036453.1
UniProt Primary Accession #
Q9Y4Z0
UniProt Related Accession #
Q9Y4Z0
GenBank Nucleotide #
NM_012321.4
NCBI Official Full Name
U6 snRNA-associated Sm-like protein LSm4 isoform 1
NCBI Official Synonym Full Names
LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
NCBI Official Symbol
LSM4
NCBI Official Synonym Symbols
GRP; YER112W
UniProt Protein Name
U6 snRNA-associated Sm-like protein LSm4
UniProt Synonym Protein Names
Glycine-rich protein; GRP
Protein Family
Probable U6 snRNA-associated Sm-like protein
UniProt Gene Name
LSM4
UniProt Synonym Gene Names
GRP
UniProt Entry Name
LSM4_HUMAN
NCBI Protein Information
U6 snRNA-associated Sm-like protein LSm4; glycine-rich protein

NCBI Summary for LSM4

This gene encodes a member of the LSm family of RNA-binding proteins. LSm proteins form stable heteromers that bind specifically to the 3'-terminal oligo(U) tract of U6 snRNA and may play a role in pre-mRNA splicing by mediating U4/U6 snRNP formation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]
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UniProt Comments for LSM4

LSM4: Binds specifically to the 3'-terminal U-tract of U6 snRNA. Belongs to the snRNP Sm proteins family.

Protein type: RNA-binding; Spliceosome

Chromosomal Location of Human Ortholog: 19p13.11

Cellular Component: small nuclear ribonucleoprotein complex; spliceosome; cytosol

Molecular Function: protein binding

Biological Process: RNA splicing; gene expression; mRNA processing; mRNA catabolic process, deadenylation-dependent decay
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Research Articles on LSM4

1. C-terminal extension of Lsm4 interacts directly with the histone mRNP, contacting both SLBP and 3'hExo.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-LSM4 antibody

 Reference Product  PubMed Publications
 LSM1 antibody  >7 publications with LSM4 and LSM1
 SNRPE antibody  >5 publications with LSM4 and SNRPE
 LSM2 antibody  >5 publications with LSM4 and LSM2
 LSM6 antibody  >4 publications with LSM4 and LSM6
 LSM3 antibody  >3 publications with LSM4 and LSM3
 LSM7 antibody  >3 publications with LSM4 and LSM7
 NAA38 antibody  >2 publications with LSM4 and NAA38
 XRN1 antibody  >2 publications with LSM4 and XRN1

Pathways associated with anti-LSM4 antibody

 Products by Pathway  Pathway Diagram
 Deadenylation-dependent MRNA Decay Pathway antibodies  Deadenylation-dependent MRNA Decay Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Lsm 1-7 Complex Pathway antibodies  Lsm 1-7 Complex Pathway Diagram
 Lsm 1-7 Complex Pathway antibodies  Lsm 1-7 Complex Pathway Diagram
 Lsm 2-8 Complex Pathway antibodies  Lsm 2-8 Complex Pathway Diagram
 Lsm 2-8 Complex Pathway antibodies  Lsm 2-8 Complex Pathway Diagram
 RNA Degradation Pathway antibodies  RNA Degradation Pathway Diagram
 RNA Degradation Pathway antibodies  RNA Degradation Pathway Diagram
 Spliceosome Pathway antibodies  Spliceosome Pathway Diagram
 Spliceosome Pathway antibodies  Spliceosome Pathway Diagram

Diseases associated with anti-LSM4 antibody

 Disease Name  Pubmed Publications
 Fetal Death Antibodies  >1 publications with LSM4 and Fetal Death
 Prostatic Diseases Antibodies  >1 publications with LSM4 and Prostatic Diseases
 Liver Diseases Antibodies  >1 publications with LSM4 and Liver Diseases
 Kidney Diseases Antibodies  >1 publications with LSM4 and Kidney Diseases
 Liver Neoplasms Antibodies  >1 publications with LSM4 and Liver Neoplasms
 Carcinoma, Hepatocellular Antibodies  >1 publications with LSM4 and Carcinoma, Hepatocellular

Organs/Tissues associated with anti-LSM4 antibody

 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >4 publications with LSM4 and Nerve
 Blood Antibodies  >2 publications with LSM4 and Blood
 Brain Antibodies  >2 publications with LSM4 and Brain
 Uterus Antibodies  >1 publications with LSM4 and Uterus
 Kidney Antibodies  >1 publications with LSM4 and Kidney
 Prostate Antibodies  >1 publications with LSM4 and Prostate
 Embryonic Tissue Antibodies  >1 publications with LSM4 and Embryonic Tissue
 Liver Antibodies  >1 publications with LSM4 and Liver
 Intestine Antibodies  >1 publications with LSM4 and Intestine
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