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LTB Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS7130004

MBS7130004 is an antibody targeting LTB. Also known as LTB Antibody. Reactive in Human, Mouse. Host: Rabbit. More details

$230 / 0.05 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
LTB, Polyclonal Antibody
Full Product Name
LTB Antibody
Product Gene Name
Product Synonym Names
lymphotoxin beta (TNF superfamily; member 3)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Liquid; In Phosphate Buffered Saline, pH 7.4, 0.05% NaN3, and 40% Glycerol
Purity/Purification
Antigen Affinity Purification
Preparation and Storage
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.
Molecular Weight
25,390 Da
Chromosome Location
Chromosome: 6; NC_000006.11 (31548335..31550202, complement). Location: 6p21.3
OMIM
600978
3D Structure
ModBase 3D Structure for Q06643
Immunogen
Synthetic peptide of human LTB
Immunogen Species
Human
Conjugate
Non-conjugated

Product Categories/Family for anti-LTB antibody

ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-LTB antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes for anti-LTB antibody
ELISA: 1:2000-1:10000
IHC: 1:30-1:150

Immunohistochemistry (IHC)-Paraffin of anti-LTB antibody

The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using MBS7130004(LTB Antibody) at dilution 1/45, on the right is treated with synthetic peptide. (Original magnification: ×200)
Rabbit Anti-LTB Polyclonal Antibody – Cat# MBS7130004

Other Notes

Small volumes of anti-LTB antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for LTB. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
lymphotoxin-beta isoform a
NCBI Official Synonym Full Names
lymphotoxin beta (TNF superfamily, member 3)
NCBI Official Symbol
LTB
NCBI Official Synonym Symbols
p33; TNFC; TNFSF3
UniProt Protein Name
Lymphotoxin-beta
UniProt Synonym Protein Names
Tumor necrosis factor C; TNF-C; Tumor necrosis factor ligand superfamily member 3
Protein Family
UniProt Gene Name
LTB
UniProt Synonym Gene Names
TNFC; TNFSF3; LT-beta; TNF-C
UniProt Entry Name
TNFC_HUMAN
NCBI Protein Information
lymphotoxin-beta; TNF-C; LT-beta; tumor necrosis factor C; tumor necrosis factor ligand superfamily member 3

NCBI Summary for LTB

Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex (e.g. 1 molecule alpha/2 molecules beta) and this complex is the primary ligand for the lymphotoxin-beta receptor. The minor complex is lymphotoxin-alpha 2/beta 1. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is unable to complex with lymphotoxin-alpha suggesting a function for lymphotoxin-beta which is independent of lympyhotoxin-alpha. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
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UniProt Comments for LTB

LTB: Cytokine that binds to LTBR/TNFRSF3. May play a specific role in immune response regulation. Provides the membrane anchor for the attachment of the heterotrimeric complex to the cell surface. Isoform 2 is probably non-functional. Belongs to the tumor necrosis factor family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 6p21.3

Cellular Component: extracellular space; integral to membrane

Molecular Function: cytokine activity; tumor necrosis factor receptor binding; receptor binding

Biological Process: skin development; positive regulation of interleukin-12 biosynthetic process; cell-cell signaling; gene expression; immune response; signal transduction; lymph node development
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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