• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

MFSD2A Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS7129289

MBS7129289 is an antibody targeting MFSD2A. Also known as MFSD2A Antibody. Reactive in Human, Mouse. Host: Rabbit. More details

$230 / 0.05 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MFSD2A, Polyclonal Antibody
Full Product Name
MFSD2A Antibody
Product Gene Name
anti-MFSD2A antibody
Product Synonym Names
major facilitator superfamily domain containing 2A
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Liquid; In Phosphate Buffered Saline, pH 7.4, 0.05% NaN3, and 40% Glycerol
Purity/Purification
Antigen Affinity Purification
Preparation and Storage
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.
Molecular Weight
50,230 Da
OMIM
AY358636 mRNA
3D Structure
ModBase 3D Structure for Q8NA29
Immunogen
Synthetic peptide of human MFSD2A
Immunogen Species
Human
Conjugate
Non-conjugated

Product Categories/Family for anti-MFSD2A antibody

Neuroscience
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-MFSD2A antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-MFSD2A antibody
ELISA: 1:1000-1:2000
WB: 1:500-1:2000
IHC: 1:25-1:100

Immunohistochemistry (IHC)-Paraffin of anti-MFSD2A antibody

The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using MBS7129289(MFSD2A Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ×200)
Rabbit Anti-MFSD2A Polyclonal Antibody – Cat# MBS7129289

Immunohistochemistry (IHC)-Paraffin of anti-MFSD2A antibody

The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using MBS7129289(MFSD2A Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ×200)
Rabbit Anti-MFSD2A Polyclonal Antibody, Immunohistochemistry (IHC)-Paraffin – Cat# MBS7129289

SDS-Page of anti-MFSD2A antibody

Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane 1-5: Human thyroid cancer tissue, mouse liver tissue, human fetal liver tissue, A549 cells, 293T cells, Primary antibody: MBS7129289(MFSD2A Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
Rabbit Anti-MFSD2A Polyclonal Antibody, SDS-Page – Cat# MBS7129289

Other Notes

Small volumes of anti-MFSD2A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for MFSD2A. It may not necessarily be applicable to this product.

NCBI GI #
211063479
NCBI GeneID
84879
NCBI Accession #
NP_001129965.1
UniProt Primary Accession #
Q8NA29
UniProt Secondary Accession #
Q6UWU5; Q96F59; Q9BRC8; A8K675
UniProt Related Accession #
Q8NA29
GenBank Nucleotide #
NM_001136493.2
NCBI Official Full Name
sodium-dependent lysophosphatidylcholine symporter 1 isoform 1
NCBI Official Synonym Full Names
major facilitator superfamily domain containing 2A
NCBI Official Symbol
MFSD2A
NCBI Official Synonym Symbols
NLS1; MFSD2; MCPH15
UniProt Protein Name
Sodium-dependent lysophosphatidylcholine symporter 1
UniProt Synonym Protein Names
Major facilitator superfamily domain-containing protein 2A
Protein Family
Sodium-dependent lysophosphatidylcholine symporter
UniProt Gene Name
MFSD2A
UniProt Synonym Gene Names
MFSD2; NLS1; NLS1; Sodium-dependent LPC symporter 1
NCBI Protein Information
sodium-dependent lysophosphatidylcholine symporter 1

NCBI Summary for MFSD2A

The protein encoded by this gene is a transmembrane protein and sodium-dependent lysophosphatidylcholine transporter. The encoded protein is involved in the establishment of the blood-brain barrier and is required for brain growth and function. Defects in this gene are a cause of a progressive microcephaly syndrome. [provided by RefSeq, Mar 2017]
Show more

UniProt Comments for MFSD2A

MFSD2: Plays a role in thermogenesis via beta-adrenergic signaling pathway. May be the main plasma membrane tunicamycin transporter. Belongs to the major facilitator superfamily. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 1p34.2

Cellular Component: endoplasmic reticulum membrane; integral component of plasma membrane; plasma membrane

Molecular Function: fatty acid transmembrane transporter activity; lysophospholipid transporter activity; phospholipid transporter activity; symporter activity

Biological Process: fatty acid transport; hippocampus development; lysophospholipid transport; phosphatidylcholine biosynthetic process; transcytosis; transmembrane transport

Disease: Microcephaly 15, Primary, Autosomal Recessive
Show more

Research Articles on MFSD2A

1. Levels of DHA-derived epoxides are lower in colon tissues from patients with ulcerative colitis than healthy and resolving mucosa. Production of these metabolites by gut endothelium requires MFSD2A; endothelial progenitor cells that overexpress MFSD2A reduce colitis in mice.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-MFSD2A antibody

 Products by Pathway  Pathway Diagram
 Glycerophospholipid Biosynthesis Pathway antibodies  Glycerophospholipid Biosynthesis Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 Phospholipid Metabolism Pathway antibodies  Phospholipid Metabolism Pathway Diagram
 Synthesis Of PC Pathway antibodies  Synthesis Of PC Pathway Diagram

Diseases associated with anti-MFSD2A antibody

 Disease Name  Pubmed Publications
 Lung Neoplasms Antibodies  >2 publications with MFSD2A and Lung Neoplasms
 Neoplasms Antibodies  >2 publications with MFSD2A and Neoplasms
 Neoplasms, Experimental Antibodies  >1 publications with MFSD2A and Neoplasms, Experimental
 Drug Hypersensitivity Antibodies  >1 publications with MFSD2A and Drug Hypersensitivity
 Fatty Liver Antibodies  >1 publications with MFSD2A and Fatty Liver
 Drug Toxicity Antibodies  >1 publications with MFSD2A and Drug Toxicity

Organs/Tissues associated with anti-MFSD2A antibody

 Organ/Tissue Name  Pubmed Publications
 Adipose Tissue Antibodies  >2 publications with MFSD2A and Adipose Tissue
 Liver Antibodies  >2 publications with MFSD2A and Liver
 Lung Antibodies  >2 publications with MFSD2A and Lung
 Connective Tissue Antibodies  >1 publications with MFSD2A and Connective Tissue
 Placenta Antibodies  >1 publications with MFSD2A and Placenta
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000