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MOBP Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9201074

MOBP may play a role in compacting or stabilizing the myelin sheath, possibly by binding the negatively charged acidic phospholipids of the cytoplasmic membrane (By similarity). More details

$240 / 0.08 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MOBP, Polyclonal Antibody
Full Product Name
MOBP Antibody (N-term)
Product Gene Name
Product Synonym Names
Myelin-associated oligodendrocyte basic protein; MOBP
Clonality
Polyclonal
Isotype
Rabbit Ig
Host
Rabbit
Species Reactivity
Human, mouse
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Concentration
Vial Concentration: 0.5 (lot specific)
Specificity
This MOBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human MOBP.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
MOBP peptide (MBS9226423) is used for blocking the activity of MOBP antibody (MBS9201074)
Molecular Weight
20959
Immunogen Sequence Positions
1-30
OMIM
600948
3D Structure
ModBase 3D Structure for Q13875
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Function
May play a role in compacting or stabilizing the myelin sheath, possibly by binding the negatively charged acidic phospholipids of the cytoplasmic membrane.
Cellular Location
Cytoplasm, perinuclear region. Note=Present in the major dense line of CNS myelin.

Product Categories/Family for anti-MOBP antibody

Applications Tested/Suitable for anti-MOBP antibody
Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)
Application Notes for anti-MOBP antibody
WB~~1:1000
IHC-P~~1:50-100
FC~~1:10~50

Western Blot (WB) of anti-MOBP antibody

Western blot analysis of MOBP Antibody (N-term) in 293 cell line lysates (35ug/lane). MOBP (arrow) was detected using the purified Pab.
Rabbit Anti-MOBP Polyclonal Antibody – Cat# MBS9201074

Western Blot (WB) of anti-MOBP antibody

Western blot analysis of MOBP Antibody (N-term) in mouse cerebellum tissue lysates (35ug/lane). MOBP (arrow) was detected using the purified Pab.
Rabbit Anti-MOBP Polyclonal Antibody, Western Blot (WB) – Cat# MBS9201074

Immunohistochemistry (IHC) of anti-MOBP antibody

Formalin-fixed and paraffin-embedded human brain reacted with MOBP Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Rabbit Anti-MOBP Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS9201074

Flow Cytometry (FC/FACS) of anti-MOBP antibody

Flow cytometric analysis of 293 cells using MOBP Antibody (N-term)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Rabbit Anti-MOBP Polyclonal Antibody, Flow Cytometry (FC/FACS) – Cat# MBS9201074

Other Notes

Small volumes of anti-MOBP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MOBP purchase

MBS9201074 is an antibody targeting MOBP. Also known as MOBP Antibody (N-term). Reactive in Human, mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for MOBP. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI Related Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
myelin-associated oligodendrocyte basic protein isoform b
NCBI Official Synonym Full Names
myelin-associated oligodendrocyte basic protein
NCBI Official Symbol
MOBP
UniProt Protein Name
Myelin-associated oligodendrocyte basic protein
UniProt Gene Name
MOBP
UniProt Entry Name
MOBP_HUMAN
NCBI Protein Information
myelin-associated oligodendrocyte basic protein

UniProt Comments for MOBP

MOBP: May play a role in compacting or stabilizing the myelin sheath, possibly by binding the negatively charged acidic phospholipids of the cytoplasmic membrane. 3 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 3p22.1

Cellular Component: mitochondrion; perinuclear region of cytoplasm

Molecular Function: structural constituent of myelin sheath

Biological Process: nervous system development
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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