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NDUFB6 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6002409

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron… More details

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Product Overview

Online Datasheet in PDF
Product Name
NDUFB6, Polyclonal Antibody
Full Product Name
NDUFB6 (NADH Dehydrogenase [Ubiquinone] 1 beta Subcomplex Subunit 6, Complex I-B17, CI-B17, NADH-ubiquinone Oxidoreductase B17 Subunit, MGC13675)
Product Gene Name
anti-NDUFB6 antibody
Product Synonym Names
Anti -NDUFB6 (NADH Dehydrogenase [Ubiquinone] 1 beta Subcomplex Subunit 6, Complex I-B17, CI-B17, NADH-ubiquinone Oxidoreductase B17 Subunit, MGC13675)
Immunogen Sequence
MTGYTPDEKL RLQQLRELRR RWLKDQELSP REPVLPPQKM GPMEKFWNKF LENKSPWRKM VHGVYKKSIF VFTHVLVPVW IIHYYMKYHV SEKPYGIVEK KSRIFPGDTI LETGEVIPPM KEFPDQHH
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Recognizes human NDUFB6. Species Crossreactivity: mouse.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
15,489 Da
Chromosome Location
Chromosome: 9; NC_000009.11 (32553524..32573182, complement). Location: 9p21.1
OMIM
603322
3D Structure
ModBase 3D Structure for O95139
Immunogen
Full length human NDUFB6, aa1-128 (NP_002484.1).

Product Categories/Family for anti-NDUFB6 antibody

Antibodies; Abs to Enzymes; Dehydrogenase
Applications Tested/Suitable for anti-NDUFB6 antibody
Western Blot (WB)
Application Notes for anti-NDUFB6 antibody
Suitable for use in Western Blot.

Western Blot (WB) of anti-NDUFB6 antibody

NDUFB6 rabbit polyclonal antibody. Western Blot analysis of NDUFB6 expression in mouse kidney.
Rabbit Anti-NDUFB6 Polyclonal Antibody – Cat# MBS6002409

Western Blot (WB) of anti-NDUFB6 antibody

Western Blot analysis of NDUFB6 expression in transfected 293T cell line by NDUFB6 polyclonal antibody. Lane 1: NDUFB6 transfected lysate (15.5kD). Lane 2: Non-transfected lysate.
Rabbit Anti-NDUFB6 Polyclonal Antibody, Western Blot (WB) – Cat# MBS6002409

Other Notes

Small volumes of anti-NDUFB6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NDUFB6 purchase

MBS6002409 is an antibody targeting NDUFB6. Also known as NDUFB6 (NADH Dehydrogenase [Ubiquinone] 1 beta Subcomplex Subunit 6, Complex I-B17, CI-B17, NADH-ubiquinone Oxidoreductase B17 Subunit, MGC13675). Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for NDUFB6. It may not necessarily be applicable to this product.

NCBI GI #
316983171
NCBI GeneID
4712
NCBI Accession #
NP_001186916.1
UniProt Primary Accession #
O95139
UniProt Secondary Accession #
Q5VYT2; Q6IB84; A8K0Y7
UniProt Related Accession #
O95139
GenBank Nucleotide #
NM_001199987.1
NCBI Official Full Name
NADH dehydrogenase
NCBI Official Synonym Full Names
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa
NCBI Official Symbol
NDUFB6
NCBI Official Synonym Symbols
CI; B17
UniProt Protein Name
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6
UniProt Synonym Protein Names
Complex I-B17; CI-B17; NADH-ubiquinone oxidoreductase B17 subunit
Protein Family
NADH dehydrogenase
UniProt Gene Name
NDUFB6
UniProt Synonym Gene Names
CI-B17
UniProt Entry Name
NDUB6_HUMAN
NCBI Protein Information
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6; NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6; CI-B17; complex I-B17; NADH-ubiquinone oxidoreductase B17 subunit; NADH-ubiquinone oxidoreductase beta subunit, 6; complex I, mitochondrial respiratory chain, B17 subunit

NCBI Summary for NDUFB6

The protein encoded by this gene is a subunit of the multisubunit NADH:ubiquinone oxidoreductase (complex I). Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Alternative splicing occurs at this locus and three transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Jan 2011]
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UniProt Comments for NDUFB6

NDUFB6: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Belongs to the complex I NDUFB6 subunit family.

Protein type: EC 1.6.5.3; Membrane protein, integral; Oxidoreductase; EC 1.6.99.3; Energy Metabolism - oxidative phosphorylation; Mitochondrial

Chromosomal Location of Human Ortholog: 9p21.1

Cellular Component: nucleoplasm; mitochondrion; mitochondrial membrane; mitochondrial inner membrane; integral to membrane; mitochondrial respiratory chain complex I

Molecular Function: NADH dehydrogenase (ubiquinone) activity

Biological Process: cellular metabolic process; mitochondrial electron transport, NADH to ubiquinone
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Research Articles on NDUFB6

1. NDUFB6 subunit is required for complex I activity.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-NDUFB6 antibody

 Reference Product  PubMed Publications
 NDUFS3 antibody  >2 publications with NDUFB6 and NDUFS3
 NDUFA12 antibody  >1 publications with NDUFB6 and NDUFA12
 NDUFA8 antibody  >1 publications with NDUFB6 and NDUFA8
 NDUFA6 antibody  >1 publications with NDUFB6 and NDUFA6

Pathways associated with anti-NDUFB6 antibody

 Products by Pathway  Pathway Diagram
 Alzheimer's Disease Pathway antibodies  Alzheimer's Disease Pathway Diagram
 Alzheimer's Disease Pathway antibodies  Alzheimer's Disease Pathway Diagram
 Electron Transport Chain Pathway antibodies  Electron Transport Chain Pathway Diagram
 Huntington's Disease Pathway antibodies  Huntington's Disease Pathway Diagram
 Huntington's Disease Pathway antibodies  Huntington's Disease Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 NADH Dehydrogenase (ubiquinone) 1 Beta Subcomplex Pathway antibodies  NADH Dehydrogenase (ubiquinone) 1 Beta Subcomplex Pathway Diagram
 Non-alcoholic Fatty Liver Disease (NAFLD) Pathway antibodies  Non-alcoholic Fatty Liver Disease (NAFLD) Pathway Diagram
 Non-alcoholic Fatty Liver Disease (NAFLD) Pathway antibodies  Non-alcoholic Fatty Liver Disease (NAFLD) Pathway Diagram
 Oxidative Phosphorylation Pathway antibodies  Oxidative Phosphorylation Pathway Diagram

Diseases associated with anti-NDUFB6 antibody

 Disease Name  Pubmed Publications
 Weight Gain Antibodies  >3 publications with NDUFB6 and Weight Gain
 Fatty Liver Antibodies  >3 publications with NDUFB6 and Fatty Liver
 Nervous System Diseases Antibodies  >2 publications with NDUFB6 and Nervous System Diseases
 Hyperglycemia Antibodies  >1 publications with NDUFB6 and Hyperglycemia
 Liver Diseases Antibodies  >1 publications with NDUFB6 and Liver Diseases
 Inflammation Antibodies  >1 publications with NDUFB6 and Inflammation

Organs/Tissues associated with anti-NDUFB6 antibody

 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >6 publications with NDUFB6 and Muscle
 Liver Antibodies  >4 publications with NDUFB6 and Liver
 Connective Tissue Antibodies  >2 publications with NDUFB6 and Connective Tissue
 Bone Antibodies  >1 publications with NDUFB6 and Bone
 Kidney Antibodies  >1 publications with NDUFB6 and Kidney
 Skin Antibodies  >1 publications with NDUFB6 and Skin
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