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NFE2L1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6324979

This gene encodes a protein that is involved in globin gene expression in erythrocytes. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene, NFE2L1, and for 'nuclear respiratory factor 1' which has an official… More details

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Product Overview

Online Datasheet in PDF
Product Name
NFE2L1, Polyclonal Antibody
Full Product Name
NFE2L1, CT (NFE2L1, HBZ17, NRF1, TCF11, Nuclear factor erythroid 2-related factor 1, Locus control region-factor 1, Nuclear factor, erythroid derived 2, like 1, Transcription factor 11, Transcription factor HBZ17, Transcription factor LCR-F1) (MaxLight 65
Product Gene Name
Product Synonym Names
NFE2L1; HBZ17; NRF1; TCF11; Nuclear factor erythroid 2-related factor 1; Locus control region-factor 1; Nuclear factor; erythroid derived 2; like 1; Transcription factor 11; Transcription factor HBZ17; Transcription factor LCR-F1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight650.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight650 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
84,704 Da
OMIM
163260
3D Structure
ModBase 3D Structure for Q14494
Immunogen
NFE2L1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 712-742 amino acids from the C-terminal region of human NFE2L1.
Conjugate
MaxLight650
Note
Preservative Free
Applications Tested/Suitable for anti-NFE2L1 antibody
Western Blot (WB), FLISA
Application Notes for anti-NFE2L1 antibody
WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-NFE2L1 antibody

Steffen, J., et al. Mol. Cell 40(1):147-158(2010). Radhakrishnan, S.K., et al. Mol. Cell 38(1):17-28(2010). Wang, W., et al. J. Biol. Chem. 282(34):24670-24678(2007). Newman, J.R., et al. Science 300(5628):2097-2101(2003). Toki, T., et al. Oncogene 14(16):1901-1910(1997).

Other Notes

Small volumes of anti-NFE2L1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NFE2L1 purchase

MBS6324979 is an antibody targeting NFE2L1. Also known as NFE2L1, CT (NFE2L1, HBZ17, NRF1, TCF11, Nuclear factor erythroid 2-related factor 1, Locus control region-factor 1, Nuclear factor, erythroid derived 2, like 1, Transcription factor 11, Transcription factor HBZ17, Transcription factor LCR-F1) (MaxLight 65. Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for NFE2L1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
nuclear factor erythroid 2-related factor 1
NCBI Official Synonym Full Names
nuclear factor, erythroid 2-like 1
NCBI Official Symbol
NFE2L1
NCBI Official Synonym Symbols
NRF1; TCF11; LCR-F1
UniProt Protein Name
Nuclear factor erythroid 2-related factor 1
UniProt Synonym Protein Names
Locus control region-factor 1; Nuclear factor, erythroid derived 2, like 1; Transcription factor 11; TCF-11; Transcription factor HBZ17; Transcription factor LCR-F1
UniProt Gene Name
NFE2L1
UniProt Synonym Gene Names
HBZ17; NRF1; TCF11; NF-E2-related factor 1; NFE2-related factor 1; TCF-11
UniProt Entry Name
NF2L1_HUMAN
NCBI Protein Information
nuclear factor erythroid 2-related factor 1; TCF-11; NFE2-related factor 1; NF-E2-related factor 1; transcription factor HBZ17; transcription factor LCR-F1; locus control region-factor 1; nuclear factor (erythroid-derived 2)-like 1; nuclear factor, erythr

NCBI Summary for NFE2L1

This gene encodes a protein that is involved in globin gene expression in erythrocytes. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene, NFE2L1, and for "nuclear respiratory factor 1" which has an official symbol of NRF1. [provided by RefSeq, Jul 2008]
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UniProt Comments for NFE2L1

NFE2L1: Activates erythroid-specific, globin gene expression. Interacts with KEAP1. Belongs to the bZIP family. CNC subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 17q21.3

Cellular Component: endoplasmic reticulum membrane; integral to membrane; nucleus

Molecular Function: transcription cofactor activity; transcription factor activity

Biological Process: transcription from RNA polymerase II promoter; anatomical structure morphogenesis; erythrocyte differentiation; positive regulation of transcription from RNA polymerase II promoter; inflammatory response; heme biosynthetic process
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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