• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

NME6 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9403496

Nucleoside diphosphate (NDP) kinases (EC 2.7.4.6), such as NME6, are ubiquitous enzymes that catalyze transfer of gamma-phosphates, via a phosphohistidine intermediate, between nucleoside and dioxynucleoside tri- and diphosphates. Major role in the synthesis… More details

$325 / 0.1 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
NME6, Polyclonal Antibody
Full Product Name
NME6 Antibody
Product Gene Name
anti-NME6 antibody
Product Synonym Names
NDK 6; NM23-H6; IPIA-ALPHA
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Purity/Purification
Antigen affinity purification.
Concentration
0.8 mg/ml (lot specific)
Specificity
The antibody detects endogenous levels of total NME6 protein.
Preparation and Storage
Store at -20 degree C
Molecular Weight
18,087 Da
OMIM
608294
3D Structure
ModBase 3D Structure for O75414
Immunogen Type
Recombinant Protein
Immunogen Description
Full length fusion protein
Target Name
NME6

Product Categories/Family for anti-NME6 antibody

Total protein Ab
Applications Tested/Suitable for anti-NME6 antibody
Western Blot (WB)
Application Notes for anti-NME6 antibody
Western blotting: 1:200-1:1000

Testing Data of anti-NME6 antibody

Gel: 10%SDS-PAGE Lysates (from left to right): Mouse spleen and intestinum crassum tissue Amount of lysate: 40ug per lane Primary antibody: 1/400 dilution Secondary antibody dilution: 1/8000 Exposure time: 1 minute
Rabbit Anti-NME6 Polyclonal Antibody – Cat# MBS9403496

Other Notes

Small volumes of anti-NME6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NME6 purchase

MBS9403496 is an antibody targeting NME6. Also known as NME6 Antibody. Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for NME6. It may not necessarily be applicable to this product.

NCBI GI #
5031951
NCBI GeneID
10201
NCBI Accession #
NP_005784.1
UniProt Primary Accession #
O75414
UniProt Secondary Accession #
Q53HM5; Q96E73; Q9BQ63; B4DGW7; B4DM99
UniProt Related Accession #
O75414
GenBank Nucleotide #
NM_005793.4
NCBI Official Full Name
nucleoside diphosphate kinase 6 isoform 1
NCBI Official Synonym Full Names
NME/NM23 nucleoside diphosphate kinase 6
NCBI Official Symbol
NME6
NCBI Official Synonym Symbols
NDK 6; NM23-H6; IPIA-ALPHA
UniProt Protein Name
Nucleoside diphosphate kinase 6
UniProt Synonym Protein Names
Inhibitor of p53-induced apoptosis-alpha; IPIA-alpha; nm23-H6
Protein Family
Nucleoside diphosphate kinase
UniProt Gene Name
NME6
UniProt Synonym Gene Names
NDK 6; NDP kinase 6; IPIA-alpha
UniProt Entry Name
NDK6_HUMAN
NCBI Protein Information
nucleoside diphosphate kinase 6

NCBI Summary for NME6

Nucleoside diphosphate (NDP) kinases (EC 2.7.4.6), such as NME6, are ubiquitous enzymes that catalyze transfer of gamma-phosphates, via a phosphohistidine intermediate, between nucleoside and dioxynucleoside tri- and diphosphates (Mehus et al., 1999 [PubMed 10453732]).[supplied by OMIM, Jul 2010]

UniProt Comments for NME6

NME6: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Inhibitor of p53-induced apoptosis. Belongs to the NDK family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Kinase, nucleoside diphosphate; EC 2.7.4.6; Nucleotide Metabolism - pyrimidine; Kinase, other; Nucleotide Metabolism - purine; Other group; NDK family

Chromosomal Location of Human Ortholog: 3p21

Cellular Component: mitochondrion

Molecular Function: metal ion binding; nucleoside diphosphate kinase activity; ATP binding

Biological Process: GTP biosynthetic process; CTP biosynthetic process; apoptosis; UTP biosynthetic process; negative regulation of mitosis; nucleoside diphosphate phosphorylation; negative regulation of cell growth
Show more

Research Articles on NME6

1. Observational study of gene-disease association. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-NME6 antibody

 Products by Pathway  Pathway Diagram
 Adenine Ribonucleotide Biosynthesis, IMP => ADP,ATP Pathway antibodies  Adenine Ribonucleotide Biosynthesis, IMP => ADP,ATP Pathway Diagram
 Adenine Ribonucleotide Biosynthesis, IMP => ADP,ATP Pathway antibodies  Adenine Ribonucleotide Biosynthesis, IMP => ADP,ATP Pathway Diagram
 Biosynthesis Of Antibiotics Pathway antibodies  Biosynthesis Of Antibiotics Pathway Diagram
 CMP Phosphorylation Pathway antibodies  CMP Phosphorylation Pathway Diagram
 Guanine Ribonucleotide Biosynthesis IMP => GDP,GTP Pathway antibodies  Guanine Ribonucleotide Biosynthesis IMP => GDP,GTP Pathway Diagram
 Guanine Ribonucleotide Biosynthesis IMP => GDP,GTP Pathway antibodies  Guanine Ribonucleotide Biosynthesis IMP => GDP,GTP Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Purine Metabolism Pathway antibodies  Purine Metabolism Pathway Diagram
 Purine Metabolism Pathway antibodies  Purine Metabolism Pathway Diagram
 Pyrimidine Metabolism Pathway antibodies  Pyrimidine Metabolism Pathway Diagram

Organs/Tissues associated with anti-NME6 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >1 publications with NME6 and Blood
 Prostate Antibodies  >1 publications with NME6 and Prostate
 Kidney Antibodies  >1 publications with NME6 and Kidney
 Intestine Antibodies  >1 publications with NME6 and Intestine
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000