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PFDN1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6332842

This gene encodes a member of the prefoldin beta subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The… More details

$1025 / 0.1 mL +1 FREE 8GB USB
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Product Overview

Online Datasheet in PDF
Product Name
PFDN1, Polyclonal Antibody
Full Product Name
PFDN1, CT (PFDN1, PFD1, Prefoldin subunit 1) (MaxLight 405)
Product Gene Name
Product Synonym Names
PFDN1; PFD1; Prefoldin subunit 1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight405.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight405 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
14,210 Da
Chromosome Location
Chromosome: 5; NC_000005.9 (139624635..139682689, complement). Location: 5q31
OMIM
604897
3D Structure
ModBase 3D Structure for O60925
Immunogen
PFDN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 85-113 amino acids from the C-terminal region of human PFDN1.
Conjugate
MaxLight405
Note
Preservative Free

Product Categories/Family for anti-PFDN1 antibody

Applications Tested/Suitable for anti-PFDN1 antibody
Western Blot (WB), FLISA
Application Notes for anti-PFDN1 antibody
WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-PFDN1 antibody

Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007): Stirling, P.C., et al. J. Biol. Chem. 281(11):7012-7021(2006). Stelzl, U., et al. Cell 122(6):957-968(2005). Simons, C.T., et al. J. Biol. Chem. 279(6):4196-4203(2004). Gstaiger, M., et al. Science 302(5648):1208-1212(2003).

Other Notes

Small volumes of anti-PFDN1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PFDN1 purchase

MBS6332842 is an antibody targeting PFDN1. Also known as PFDN1, CT (PFDN1, PFD1, Prefoldin subunit 1) (MaxLight 405). Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PFDN1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
prefoldin subunit 1
NCBI Official Synonym Full Names
prefoldin subunit 1
NCBI Official Symbol
PFDN1
NCBI Official Synonym Symbols
PDF; PFD1
UniProt Protein Name
Prefoldin subunit 1
Protein Family
UniProt Gene Name
PFDN1
UniProt Synonym Gene Names
PFD1
UniProt Entry Name
PFD1_HUMAN
NCBI Protein Information
prefoldin subunit 1; prefoldin 1

UniProt Comments for PFDN1

PFDN1: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins. Belongs to the prefoldin subunit beta family.

Protein type: Chaperone

Chromosomal Location of Human Ortholog: 5q31

Cellular Component: prefoldin complex

Molecular Function: unfolded protein binding; transcription factor activity

Biological Process: 'de novo' posttranslational protein folding; telencephalon development; cellular protein metabolic process; B cell activation; regulation of transcription, DNA-dependent; protein folding; cerebellum development; actin cytoskeleton organization and biogenesis; cell cycle
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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