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PGD Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6333022

6-phosphogluconate dehydrogenase is the second dehydrogenase in the pentose phosphate shunt. Deficiency of this enzyme is generally asymptomatic, and the inheritance of this disorder is autosomal dominant. Hemolysis results from combined deficiency of… More details

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Product Overview

Online Datasheet in PDF
Product Name
PGD, Polyclonal Antibody
Full Product Name
PGD, ID (PGD, PGDH, 6-phosphogluconate dehydrogenase, decarboxylating) (MaxLight 750)
Product Gene Name
Product Synonym Names
PGD; PGDH; 6-phosphogluconate dehydrogenase; decarboxylating
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight750.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight750 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
53,140 Da
Chromosome Location
Chromosome: 1; NC_000001.10 (10459085..10480201). Location: 1p36.22
OMIM
172200
3D Structure
ModBase 3D Structure for P52209
Immunogen
PGD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 242-271 amino acids from the Central region of human PGD.
Conjugate
MaxLight750
Note
Preservative Free

Product Categories/Family for anti-PGD antibody

Applications Tested/Suitable for anti-PGD antibody
Flow Cytometry (FC/FACS), FLISA, Immunohistochemistry (IHC), Western Blot (WB)
Application Notes for anti-PGD antibody
FC/FACS: 1:10-50
FLISA: 1:1,000
IHC: 1:50-100
WB: 1:100-500
Applications are based on unconjugated antibody.

Product References and Citations for anti-PGD antibody

Lehner, B., et al. Genome Res. 14(7):1315-1323(2004). Kerimov, B.F. Vopr. Med. Khim. 48(5):490-496(2002). Rippa, M., et al. Biochim. Biophys. Acta 1429(1):83-92(1998).

Other Notes

Small volumes of anti-PGD antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PGD purchase

MBS6333022 is an antibody targeting PGD. Also known as PGD, ID (PGD, PGDH, 6-phosphogluconate dehydrogenase, decarboxylating) (MaxLight 750). Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PGD. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
6-phosphogluconate dehydrogenase, decarboxylating
NCBI Official Synonym Full Names
phosphogluconate dehydrogenase
NCBI Official Symbol
PGD
NCBI Official Synonym Symbols
6PGD
UniProt Protein Name
6-phosphogluconate dehydrogenase, decarboxylating
UniProt Gene Name
PGD
UniProt Synonym Gene Names
PGDH
UniProt Entry Name
6PGD_HUMAN
NCBI Protein Information
6-phosphogluconate dehydrogenase, decarboxylating

UniProt Comments for PGD

PGD: an oxidative carboxylase that catalyses the decarboxylating reduction of 6-phosphogluconate into ribulose 5-phosphate in the presence of NADP. This reaction is a component of the hexose mono-phosphate shunt and pentose phosphate pathways.

Protein type: Oxidoreductase; Carbohydrate Metabolism - pentose phosphate pathway; Other Amino Acids Metabolism - glutathione; EC 1.1.1.44

Chromosomal Location of Human Ortholog: 1p36.22

Cellular Component: nucleus; cytosol

Molecular Function: phosphogluconate dehydrogenase (decarboxylating) activity; NADP binding

Biological Process: pentose-phosphate shunt; pentose-phosphate shunt, oxidative branch; carbohydrate metabolic process; pathogenesis; D-gluconate metabolic process; pentose biosynthetic process
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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