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PLEXIN B1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9401285

MBS9401285 is an antibody targeting Plexin B1. Also known as Plexin B1 Antibody. Reactive in Human, Mouse. Host: Rabbit. More details

$440 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Plexin B1, Polyclonal Antibody
Full Product Name
Plexin B1 Antibody
Product Gene Name
anti-Plexin B1 antibody
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
PBS, pH 7.4 with 0.02% Sodium Azide
Purity/Purification
Protein A purified
Concentration
1.0 mg/ml (lot specific)
Specificity
Plexin B1 antibody detects endogenous levels of Plexin B1 protein. Not tested with other proteins
Preparation and Storage
This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Molecular Weight
78,395 Da
OMIM
601053
Immunogen Type
Peptide-KLH
Immunogen Description
Synthetic peptide conjugated to KLH
Target Name
Plexin B1

Product Categories/Family for anti-Plexin B1 antibody

Total protein Ab
Applications Tested/Suitable for anti-Plexin B1 antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-Plexin B1 antibody
ELISA: 1:200
WB: 1:200

Testing Data of anti-Plexin B1 antibody

Rabbit Anti-PLEXIN B1 Polyclonal Antibody – Cat# MBS9401285

Other Notes

Small volumes of anti-Plexin B1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Plexin B1. It may not necessarily be applicable to this product.

NCBI GI #
194272180
NCBI GeneID
5364
NCBI Accession #
NP_001123554.1
UniProt Secondary Accession #
Q6NY20; Q9UIV7; Q9UJ92; Q9UJ93; A6H8Y2
UniProt Related Accession #
O43157
GenBank Nucleotide #
NM_001130082.2
NCBI Official Full Name
plexin-B1
NCBI Official Synonym Full Names
plexin B1
NCBI Official Symbol
PLXNB1
NCBI Official Synonym Symbols
SEP; PLXN5; PLEXIN-B1
UniProt Protein Name
Plexin-B1
UniProt Synonym Protein Names
Semaphorin receptor SEP
Protein Family
Plexin
UniProt Gene Name
PLXNB1
UniProt Synonym Gene Names
KIAA0407; PLXN5; SEP
UniProt Entry Name
PLXB1_HUMAN
NCBI Protein Information
plexin-B1

UniProt Comments for Plexin B1

PLXNB1: Receptor for SEMA4D. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Belongs to the plexin family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; Membrane protein, integral; Receptor, misc.

Chromosomal Location of Human Ortholog: 3p21.31

Cellular Component: integral to plasma membrane; extracellular region; plasma membrane; intracellular

Molecular Function: protein binding; transmembrane receptor activity; semaphorin receptor activity; GTPase activating protein binding; receptor activity; semaphorin receptor binding

Biological Process: positive regulation of phosphoinositide 3-kinase cascade; axon guidance; regulation of cell shape; cell migration; positive regulation of axonogenesis; negative regulation of osteoblast proliferation; negative regulation of cell adhesion; signal transduction; neurite morphogenesis; regulation of cytoskeleton organization and biogenesis
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Research Articles on Plexin B1

1. The Semaphorin 4D-Plexin-B1-RhoA signaling axis recruits pericytes and regulates vascular permeability through endothelial production of PDGF-B and ANGPTL4.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-Plexin B1 antibody

 Reference Product  PubMed Publications
 SEMA4D antibody  >71 publications with Plexin B1 and SEMA4D
 RHOA antibody  >22 publications with Plexin B1 and RHOA
 MET antibody  >20 publications with Plexin B1 and MET
 RAC1 antibody  >11 publications with Plexin B1 and RAC1
 RND1 antibody  >6 publications with Plexin B1 and RND1
 RRAS antibody  >3 publications with Plexin B1 and RRAS
 ARHGEF12 antibody  >3 publications with Plexin B1 and ARHGEF12
 ARHGEF11 antibody  >3 publications with Plexin B1 and ARHGEF11
 RAC3 antibody  >1 publications with Plexin B1 and RAC3

Pathways associated with anti-Plexin B1 antibody

 Products by Pathway  Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 G Alpha (12/13) Signalling Events Pathway antibodies  G Alpha (12/13) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 Sema4D In Semaphorin Signaling Pathway antibodies  Sema4D In Semaphorin Signaling Pathway Diagram
 Sema4D Induced Cell Migration And Growth-cone Collapse Pathway antibodies  Sema4D Induced Cell Migration And Growth-cone Collapse Pathway Diagram
 Sema4D Mediated Inhibition Of Cell Attachment And Migration Pathway antibodies  Sema4D Mediated Inhibition Of Cell Attachment And Migration Pathway Diagram
 Semaphorin Interactions Pathway antibodies  Semaphorin Interactions Pathway Diagram

Diseases associated with anti-Plexin B1 antibody

 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >6 publications with Plexin B1 and Breast Neoplasms
 Inflammation Antibodies  >3 publications with Plexin B1 and Inflammation
 Cardiovascular Diseases Antibodies  >3 publications with Plexin B1 and Cardiovascular Diseases
 Kidney Diseases Antibodies  >2 publications with Plexin B1 and Kidney Diseases
 Necrosis Antibodies  >2 publications with Plexin B1 and Necrosis
 Neural Tube Defects Antibodies  >1 publications with Plexin B1 and Neural Tube Defects
 Liver Neoplasms, Experimental Antibodies  >1 publications with Plexin B1 and Liver Neoplasms, Experimental
 Liver Diseases Antibodies  >1 publications with Plexin B1 and Liver Diseases
 Carcinoma, Hepatocellular Antibodies  >1 publications with Plexin B1 and Carcinoma, Hepatocellular
 Cell Transformation, Neoplastic Antibodies  >1 publications with Plexin B1 and Cell Transformation, Neoplastic

Organs/Tissues associated with anti-Plexin B1 antibody

 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >125 publications with Plexin B1 and Nerve
 Brain Antibodies  >22 publications with Plexin B1 and Brain
 Embryonic Tissue Antibodies  >19 publications with Plexin B1 and Embryonic Tissue
 Vascular Antibodies  >14 publications with Plexin B1 and Vascular
 Bone Antibodies  >11 publications with Plexin B1 and Bone
 Kidney Antibodies  >10 publications with Plexin B1 and Kidney
 Skin Antibodies  >8 publications with Plexin B1 and Skin
 Lung Antibodies  >6 publications with Plexin B1 and Lung
 Lymph Node Antibodies  >6 publications with Plexin B1 and Lymph Node
 Prostate Antibodies  >5 publications with Plexin B1 and Prostate
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