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PLTP Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS613178

Plasma phospholipid transfer protein (PLTP) plays a central role in regulating plasma HDL levels and distribution of HDL subpopulations. This regulation is evidenced in vivo by markedly reduced plasma HDL levels in PLTP gene knock-out mice. PLTP also… More details

$805 / 0.2 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
PLTP, Polyclonal Antibody
Full Product Name
PLTP (Plasma Phospholipid Transfer Protein)
Product Gene Name
Product Synonym Names
Anti -PLTP (Plasma Phospholipid Transfer Protein)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Supplied as a liquid in 0.02% sodium azide.
Purity/Purification
Serum
Serum
Specificity
Specific for human Phospholipid Transfer Protein (PLTP), ~78kD. Based on sequence homology, is expected to recognize mouse PLTP.
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
54,739 Da
Chromosome Location
Chromosome: 20; NC_000020.10 (44527397..44540786, complement). Location: 20q13.12
OMIM
172425
3D Structure
ModBase 3D Structure for P55058
Immunogen
aa470-490 of human PLTP (EVIEKNRPADVRASTAPTPST)
Applications Tested/Suitable for anti-PLTP antibody
Western Blot (WB)
Application Notes for anti-PLTP antibody
Suitable for use in Western Blot (non-neutralizing). This antibody does not exhibit neutralizing activity.
Dilution: Western Blot: 1:500-1:1000

Other Notes

Small volumes of anti-PLTP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PLTP purchase

MBS613178 is an antibody targeting PLTP. Also known as PLTP (Plasma Phospholipid Transfer Protein). Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PLTP. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
phospholipid transfer protein isoform b
NCBI Official Synonym Full Names
phospholipid transfer protein
NCBI Official Symbol
PLTP
NCBI Official Synonym Symbols
HDLCQ9
UniProt Protein Name
Phospholipid transfer protein
UniProt Synonym Protein Names
Lipid transfer protein II
UniProt Gene Name
PLTP
UniProt Entry Name
PLTP_HUMAN
NCBI Protein Information
phospholipid transfer protein; OTTHUMP00000031678; OTTHUMP00000031679; OTTHUMP00000214864; OTTHUMP00000214865; OTTHUMP00000214866; lipid transfer protein II

NCBI Summary for PLTP

The protein encoded by this gene is one of at least two lipid transfer proteins found in human plasma. The encoded protein transfers phospholipids from triglyceride-rich lipoproteins to high density lipoprotein (HDL). In addition to regulating the size of HDL particles, this protein may be involved in cholesterol metabolism. At least two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
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UniProt Comments for PLTP

PLTP: Converts HDL into larger and smaller particles. May play a key role in extracellular phospholipid transport and modulation of hdl particles. Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Lipid-binding; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 20q13.12

Cellular Component: extracellular space; extracellular region

Molecular Function: lipid binding

Biological Process: sperm motility; vitamin E biosynthetic process; lipid metabolic process; lipid transport
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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