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PPM1G Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9209298

PPM1G is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors,… More details

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Product Overview

Online Datasheet in PDF
Product Name
PPM1G, Polyclonal Antibody
Full Product Name
PPM1G Antibody (Center)
Product Gene Name
anti-PPM1G antibody
Product Synonym Names
Protein phosphatase 1G; Protein phosphatase 1C; Protein phosphatase 2C isoform gamma; PP2C-gamma; Protein phosphatase magnesium-dependent 1 gamma; PPM1G; PPM1C
Clonality
Polyclonal
Isotype
Rabbit Ig
Host
Rabbit
Species Reactivity
Human, mouse
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Purity/Purification
Purified Rabbit Polyclonal Antibody (Pab)
Concentration
Vial Concentration: 2 (lot specific)
Specificity
This PPM1G antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 150-180 amino acids from the Central region of human PPM1G.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Molecular Weight
59272
Immunogen Sequence Positions
150-180
OMIM
605119
3D Structure
ModBase 3D Structure for O15355
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN

Product Categories/Family for anti-PPM1G antibody

Cell Biology; Signal transduction
Applications Tested/Suitable for anti-PPM1G antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-PPM1G antibody
WB~~1:1000

Western Blot (WB) of anti-PPM1G antibody

Western blot analysis of hPPM1G-C164 in 293 cell line lysates (35ug/lane). PPM1G (arrow) was detected using the purified Pab.
Rabbit Anti-PPM1G Polyclonal Antibody – Cat# MBS9209298

Western Blot (WB) of anti-PPM1G antibody

Western blot analysis of hPPM1G-C164 in mouse heart tissue lysates (35ug/lane). PPM1G (arrow) was detected using the purified Pab.
Rabbit Anti-PPM1G Polyclonal Antibody, Western Blot (WB) – Cat# MBS9209298

Other Notes

Small volumes of anti-PPM1G antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PPM1G purchase

MBS9209298 is an antibody targeting PPM1G. Also known as PPM1G Antibody (Center). Reactive in Human, mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for PPM1G. It may not necessarily be applicable to this product.

NCBI GI #
29826282
NCBI GeneID
5496
NCBI Accession #
NP_817092.1
UniProt Primary Accession #
O15355
UniProt Related Accession #
O15355
GenBank Nucleotide #
NM_177983.2
NCBI Official Full Name
protein phosphatase 1G
NCBI Official Synonym Full Names
protein phosphatase, Mg2+/Mn2+ dependent, 1G
NCBI Official Symbol
PPM1G
NCBI Official Synonym Symbols
PP2CG; PPP2CG; PP2CGAMMA
UniProt Protein Name
Protein phosphatase 1G
UniProt Synonym Protein Names
Protein phosphatase 1C; Protein phosphatase 2C isoform gamma; PP2C-gamma; Protein phosphatase magnesium-dependent 1 gamma
Protein Family
Protein phosphatase
UniProt Gene Name
PPM1G
UniProt Synonym Gene Names
PPM1C; PP2C-gamma
UniProt Entry Name
PPM1G_HUMAN
NCBI Protein Information
protein phosphatase 1G

NCBI Summary for PPM1G

The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors, which is important for the formation of functional spliceosome. Studies of a similar gene in mice suggested a role of this phosphatase in regulating cell cycle progression. [provided by RefSeq, Apr 2010]
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UniProt Comments for PPM1G

PPM1G: is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors, which is important for the formation of functional spliceosome. Studies of a similar gene in mice suggested a role of this phosphatase in regulating cell cycle progression. [provided by RefSeq, Apr 2010]

Protein type: Spliceosome; Protein phosphatase, Ser/Thr (non-receptor); EC 3.1.3.16; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 2p23.3

Cellular Component: nucleoplasm; cytoplasm; nucleus

Molecular Function: protein binding; metal ion binding; protein serine/threonine phosphatase activity

Biological Process: protein amino acid dephosphorylation; cell cycle arrest
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Research Articles on PPM1G

1. PPM1G inactivates monomeric WWP2 and promotes the assembly of WWP2-WWP1 heterodimeric complex.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-PPM1G antibody

 Reference Product  PubMed Publications
 EIF4EBP1 antibody  >1 publications with PPM1G and EIF4EBP1

Diseases associated with anti-PPM1G antibody

 Disease Name  Pubmed Publications
 Death Antibodies  >3 publications with PPM1G and Death
 Cardiovascular Diseases Antibodies  >1 publications with PPM1G and Cardiovascular Diseases
 Necrosis Antibodies  >1 publications with PPM1G and Necrosis

Organs/Tissues associated with anti-PPM1G antibody

 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >1 publications with PPM1G and Nerve
 Embryonic Tissue Antibodies  >1 publications with PPM1G and Embryonic Tissue
 Blood Antibodies  >1 publications with PPM1G and Blood
 Brain Antibodies  >1 publications with PPM1G and Brain
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