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RAB5B Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6339865

MBS6339865 is an antibody targeting RAB5B. Also known as RAB5B, ID (RAB5B, Ras-related protein Rab-5B) (PE). Reactive in Human, Mouse. Host: Rabbit. More details

$1060 / 0.2 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
RAB5B, Polyclonal Antibody
Full Product Name
RAB5B, ID (RAB5B, Ras-related protein Rab-5B) (PE)
Product Gene Name
Product Synonym Names
RAB5B; Ras-related protein Rab-5B
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).
Purity/Purification
Purified by Protein A and Peptide Affinity Chromatography.
Specificity
Recognizes human RAB5B. Species Crossreactivity: mouse
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
19,090 Da
OMIM
179514
3D Structure
ModBase 3D Structure for P61020
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 85-112 in the central region of human RAB5B Swiss/UniProt Accession: P61020. Species sequence homology: chicken
Conjugate
PE
Note
Preservative Free
Special Handling
Light sensitive

Product Categories/Family for anti-RAB5B antibody

Applications Tested/Suitable for anti-RAB5B antibody
Western Blot (WB), FLISA
Application Notes for anti-RAB5B antibody
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-RAB5B antibody

Western Blot analysis in HepG2 cell line lysates (35ug/lane) usingMBS6008086. This demonstrates that MBS6008086 detected the RAB5B protein (arrow).
Rabbit Anti-RAB5B Polyclonal Antibody – Cat# MBS6339865

Western Blot (WB) of anti-RAB5B antibody

Western Blot analysis in mouse liver tissue lysates (35ug/lane) usingMBS6008086.This demonstrates that MBS6008086 detected the RAB5B protein (arrow).
Rabbit Anti-RAB5B Polyclonal Antibody, Western Blot (WB) – Cat# MBS6339865

Product References and Citations for anti-RAB5B antibody

1. Jin, Y., et al. Nat. Genet. 42(7):576-578(2010). 2. Chen, P.I., et al. J. Biol. Chem. 284(44):30328-30338(2009). 3. Shin, N., et al. Exp. Cell Res. 314(10):2055-2065(2008). 4. Hakonarson, H., et al. Diabetes 57(4):1143-1146(2008). 5. Hirota, Y., et al. Biochem. Biophys. Res. Commun. 364(1):40-47(2007).

Other Notes

Small volumes of anti-RAB5B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for RAB5B. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
ras-related protein Rab-5B isoform 1
NCBI Official Synonym Full Names
RAB5B, member RAS oncogene family
NCBI Official Symbol
RAB5B
UniProt Protein Name
Ras-related protein Rab-5B
UniProt Gene Name
RAB5B
UniProt Entry Name
RAB5B_HUMAN
NCBI Protein Information
ras-related protein Rab-5B

UniProt Comments for RAB5B

RAB5B: Protein transport. Probably involved in vesicular traffic. Belongs to the small GTPase superfamily. Rab family.

Protein type: G protein; G protein, monomeric, Rab; G protein, monomeric

Chromosomal Location of Human Ortholog: 12q13

Cellular Component: membrane; endocytic vesicle; early endosome membrane; early endosome; plasma membrane; melanosome; intracellular; endosome

Molecular Function: GTPase activity; protein binding; GDP binding; GTP binding; GTP-dependent protein binding

Biological Process: antigen processing and presentation; intracellular protein transport; endosome organization and biogenesis; metabolic process; regulation of endocytosis; plasma membrane to endosome transport; Rab protein signal transduction
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-RAB5B antibody

 Reference Product  PubMed Publications
 EEA1 antibody  >2 publications with RAB5B and EEA1
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