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RIPK4 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9466542

The protein encoded by this gene is a serine/threonine protein kinase that interacts with protein kinase C-delta. The encoded protein can also activate NFkappaB and is required for keratinocyte differentiation. This kinase undergoes autophosphorylation. More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
RIPK4, Polyclonal Antibody
Full Product Name
RIPK4 Rabbit Polyclonal Antibody
Product Gene Name
anti-RIPK4 antibody
Product Synonym Names
RIPK4; ANKK2; ANKRD3; DIK; NKRD3; PKK; PPS2; RIP4
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purity/Purification
Affinity purification
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
Molecular Weight
86,441 Da
OMIM
phenotype 605706
3D Structure
ModBase 3D Structure for P57078
Immunogen
Recombinant fusion protein of human RIPK4 (NP_065690.2).

Product Categories/Family for anti-RIPK4 antibody

Primary Antibody
Applications Tested/Suitable for anti-RIPK4 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-RIPK4 antibody
WB: 1:500-1:2000
IHC: 1:100-1:200

Immunohistochemistry (IHC) of anti-RIPK4 antibody

Immunohistochemistry of paraffin-embedded human liver damage using RIPK4 at dilution of 1:100 (40x lens).
Rabbit Anti-RIPK4 Polyclonal Antibody – Cat# MBS9466542

Immunohistochemistry (IHC) of anti-RIPK4 antibody

Immunohistochemistry of paraffin-embedded human stomach using RIPK4 at dilution of 1:100 (40x lens).
Rabbit Anti-RIPK4 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS9466542

Western Blot (WB) of anti-RIPK4 antibody

Western blot analysis of extracts of various cell lines, using RIPK4 at 1:1000 dilution.
Rabbit Anti-RIPK4 Polyclonal Antibody, Western Blot (WB) – Cat# MBS9466542

Other Notes

Small volumes of anti-RIPK4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RIPK4 purchase

MBS9466542 is an antibody targeting RIPK4. Also known as RIPK4 Rabbit Polyclonal Antibody. Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for RIPK4. It may not necessarily be applicable to this product.

NCBI GI #
41327754
NCBI GeneID
54101
NCBI Accession #
NP_065690.2
UniProt Primary Accession #
P57078
UniProt Secondary Accession #
Q96KH0
UniProt Related Accession #
P57078
GenBank Nucleotide #
NM_020639.2
NCBI Official Full Name
receptor-interacting serine/threonine-protein kinase 4
NCBI Official Synonym Full Names
receptor-interacting serine-threonine kinase 4
NCBI Official Symbol
RIPK4
NCBI Official Synonym Symbols
DIK; PKK; PPS2; RIP4; ANKK2; NKRD3; ANKRD3
UniProt Protein Name
Receptor-interacting serine/threonine-protein kinase 4
UniProt Synonym Protein Names
Ankyrin repeat domain-containing protein 3; PKC-delta-interacting protein kinase
Protein Family
Receptor-interacting serine/threonine-protein kinase
UniProt Gene Name
RIPK4
UniProt Synonym Gene Names
ANKRD3; DIK
UniProt Entry Name
RIPK4_HUMAN
NCBI Protein Information
receptor-interacting serine/threonine-protein kinase 4; protein kinase C-associated kinase; PKC-delta-interacting protein kinase; serine/threonine-protein kinase ANKRD3; ankyrin repeat domain-containing protein 3

UniProt Comments for RIPK4

ANKRD3: a TKL protein kinase of the RIPK family. Activates NFkappaB when overexpressed in cell lines and is required for keratinocyte differentiation in vivo. Appears to activate NFkappaB in both a kinase-dependent as well as a kinase-independent manner. Contains 10 ANK repeats. Two alternatively spliced isoforms have been described.

Protein type: Protein kinase, Ser/Thr (non-receptor); EC 2.7.11.1; Protein kinase, TKL; Kinase, protein; TKL group; RIPK family

Chromosomal Location of Human Ortholog: 21q22.3

Cellular Component: membrane; cytoplasm; nucleus

Molecular Function: protein serine/threonine kinase activity; protein binding; ATP binding

Biological Process: morphogenesis of an epithelium; protein amino acid phosphorylation; activation of NF-kappaB transcription factor

Disease: Popliteal Pterygium Syndrome, Lethal Type
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Research Articles on RIPK4

1. phosphorylation of DVL2 by RIPK4 favored canonical Wnt signaling; findings suggest that RIPK4 overexpression may contribute to the growth of certain tumor types

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-RIPK4 antibody

 Organ/Tissue Name  Pubmed Publications
 Skin Antibodies  >6 publications with RIPK4 and Skin
 Bone Antibodies  >3 publications with RIPK4 and Bone
 Embryonic Tissue Antibodies  >1 publications with RIPK4 and Embryonic Tissue
 Heart Antibodies  >1 publications with RIPK4 and Heart
 Liver Antibodies  >1 publications with RIPK4 and Liver
 Eye Antibodies  >1 publications with RIPK4 and Eye
 Brain Antibodies  >1 publications with RIPK4 and Brain
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