Rabbit Anti-SAMD8 Polyclonal Antibody – Cat# MBS8551619

SAMD8 Antibody – Rabbit Polyclonal

Name: SAMD8 Antibody; Polyclonal; Rabbit; Human/Mouse-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS8551619
Price: 380 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8551619

MBS8551619 is an antibody targeting SAMD8. Also known as SAMD8 (N-Term) Rabbit pAb. Reactive in Human, Mouse. Host: Rabbit. More details

$380 / 0.1 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

SAMD8, Polyclonal Antibody

Full Product Name

SAMD8 (N-Term) Rabbit pAb

Product Gene Name

anti-SAMD8 antibody

Product Synonym Names

Sphingomyelin synthase-related protein 1; SMSr; 278-; Ceramide phosphoethanolamine synthase; CPE synthase; Sterile alpha motif domain-containing protein 8; SAM domain-containing protein 8; SAMD8

Clonality

Polyclonal

Isotype

Clone Number

RB31781

Host

Rabbit

Species Reactivity

Human, Mouse

Form/Format

Supplied in PBS with 0.09% (W/V) Sodium Azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Purity/Purification

Affinity Purified

OMIM

611575

3D Structure

ModBase 3D Structure for Q96LT4

Immunogen

This SAMD8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 38-67 amino acids from the N-terminal region of human SAMD8.

Cellular Localization

Endoplasmic Reticulum, Membrane

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for anti-SAMD8 antibody

Western Blot (WB)

Application Notes for anti-SAMD8 antibody

WB: 1:1000

Other Notes

Small volumes of anti-SAMD8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SAMD8. It may not necessarily be applicable to this product.

NCBI GI #

292658773

NCBI Accession #

NP_001167627.1

UniProt Primary Accession #

Q96LT4

GenBank Nucleotide #

NP_001167627.1

NCBI Official Full Name

sphingomyelin synthase-related protein 1 isoform 1

UniProt Protein Name

Sphingomyelin synthase-related protein 1

UniProt Synonym Protein Names

Ceramide phosphoethanolamine synthase; CPE synthase; Sterile alpha motif domain-containing protein 8

Protein Family

Sphingomyelin synthase-related protein

UniProt Gene Name

SAMD8

UniProt Synonym Gene Names

SMSr; CPE synthase

UniProt Entry Name

SAMD8_HUMAN

UniProt Comments for SAMD8

SAMD8: Sphingomyelin synthases synthesize sphingolipids through transfer of a phosphatidyl head group on to the primary hydroxyl of ceramide. SAMD8 is an endoplasmic reticulum (ER) transferase that has no sphingomyelin synthase activity but can convert phosphatidylethanolamine (PE) and ceramide to ceramide phosphoethanolamine (CPE) albeit with low product yield. Appears to operate as a ceramide sensor to control ceramide homeostasis in the endoplasmic reticulum rather than a converter of ceramides. Seems to be critical for the integrity of the early secretory pathway. Belongs to the sphingomyelin synthase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell surface; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 10q22.2

Cellular Component: integral to membrane; integral to endoplasmic reticulum membrane

Molecular Function: transferase activity

Biological Process: ceramide biosynthetic process; sphingomyelin biosynthetic process

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SAMD8 antibody

Reference Product	PubMed Publications
ANKS3 antibody	>1 publications with SAMD8 and ANKS3

Pathways associated with anti-SAMD8 antibody

Products by Pathway	Pathway Diagram
Sphingomyelin Metabolism Pathway antibodies	Sphingomyelin Metabolism Pathway Diagram