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SAMD8 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9523775

MBS9523775 is an antibody targeting SAMD8. Also known as SAMD8 Antibody. Reactive in Human, Mouse. Host: Rabbit. More details

$265 / 0.04 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SAMD8, Polyclonal Antibody
Full Product Name
SAMD8 Antibody
Product Gene Name
anti-SAMD8 antibody
Product Synonym Names
Sphingomyelin synthase-related protein 1 (SMSr)(EC 2.7.8.-)(Ceramide phosphoethanolamine synthase)(CPE synthase)(Sterile alpha motif domain-containing protein 8)(SAM domain-containing protein 8)
Clonality
Polyclonal
Isotype
Rabbit IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1mg/ml (lot specific)
Specificity
This antibody detects endogenous levels of SAMD8 at Human, Mouse
Preparation and Storage
Store at -20 degree C/1 year
Molecular Weight
48,321 Da
OMIM
611575
3D Structure
ModBase 3D Structure for Q96LT4
Immunogen
Synthesized peptide derived from human SAMD8
Modification
Unmodified/Total

Product Categories/Family for anti-SAMD8 antibody

Primary Antibodies
Applications Tested/Suitable for anti-SAMD8 antibody
Western Blot (WB)
Application Notes for anti-SAMD8 antibody
WB: 1:500-2000

Other Notes

Small volumes of anti-SAMD8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SAMD8. It may not necessarily be applicable to this product.

NCBI GI #
292658773
NCBI GeneID
142891
NCBI Accession #
NP_001167627.1
UniProt Primary Accession #
Q96LT4
UniProt Secondary Accession #
Q5JSC5; Q5JSC8; Q66K52
UniProt Related Accession #
Q96LT4
GenBank Nucleotide #
NM_001174156.1
NCBI Official Full Name
sphingomyelin synthase-related protein 1 isoform 1
NCBI Official Synonym Full Names
sterile alpha motif domain containing 8
NCBI Official Symbol
SAMD8
NCBI Official Synonym Symbols
SMSr; HEL-177
UniProt Protein Name
Sphingomyelin synthase-related protein 1
UniProt Synonym Protein Names
Ceramide phosphoethanolamine synthase; CPE synthase; Sterile alpha motif domain-containing protein 8
Protein Family
Sphingomyelin synthase-related protein
UniProt Gene Name
SAMD8
UniProt Synonym Gene Names
SMSr; CPE synthase
UniProt Entry Name
SAMD8_HUMAN
NCBI Protein Information
sphingomyelin synthase-related protein 1; CPE synthase; epididymis luminal protein 177; sphingomyelin synthase related; SAM domain-containing protein 8; ceramide phosphoethanolamine synthase; sterile alpha motif domain-containing protein 8

UniProt Comments for SAMD8

SAMD8: Sphingomyelin synthases synthesize sphingolipids through transfer of a phosphatidyl head group on to the primary hydroxyl of ceramide. SAMD8 is an endoplasmic reticulum (ER) transferase that has no sphingomyelin synthase activity but can convert phosphatidylethanolamine (PE) and ceramide to ceramide phosphoethanolamine (CPE) albeit with low product yield. Appears to operate as a ceramide sensor to control ceramide homeostasis in the endoplasmic reticulum rather than a converter of ceramides. Seems to be critical for the integrity of the early secretory pathway. Belongs to the sphingomyelin synthase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell surface; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 10q22.2

Cellular Component: integral to membrane; integral to endoplasmic reticulum membrane

Molecular Function: transferase activity

Biological Process: ceramide biosynthetic process; sphingomyelin biosynthetic process
Show more

Research Articles on SAMD8

1. Observational study of gene-disease association. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SAMD8 antibody

 Reference Product  PubMed Publications
 ANKS3 antibody  >1 publications with SAMD8 and ANKS3

Pathways associated with anti-SAMD8 antibody

 Products by Pathway  Pathway Diagram
 Sphingomyelin Metabolism Pathway antibodies  Sphingomyelin Metabolism Pathway Diagram
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