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STAT6 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS4750128

STAT6 transcription factor of the STAT family. Plays a central role in IL4-mediated biological responses. Induces the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. More details

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Product Overview

Product Name
STAT6, Polyclonal Antibody
Full Product Name
Anti-STAT6 Rabbit pAb
Product Gene Name
Product Synonym Names
IL-4-STAT; Signal transducer and activator of transcription 6; interleukin-4 induced; STAT; interleukin4-induced; STAT6; STAT6B; STAT6C; transcription factor IL-4 STAT
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity Chromatography
Specificity
STAT6 Antibody detects endogenous levels of total STAT6
Preparation and Storage
Store at 4 degree C for short term.
Store at-20 degree C for long term.
Avoid freeze/thaw cycle.
Molecular Weight
94kDa
OMIM
601512
3D Structure
ModBase 3D Structure for P42226
Immunogen
A synthesized peptide derived from human STAT6
Subcellular Location
Nucleus; Nucleolus
Applications Tested/Suitable for anti-STAT6 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP)
Application Notes for anti-STAT6 antibody
WB: 1:500-1:2000
IHC: 1:50-1:200
ICC/IF: 1:50-1:200
IP: 1:50

Western Blot (WB) of anti-STAT6 antibody

Western blot analysis of STAT6 expression in Raji cell lysate.
Rabbit Anti-STAT6 Polyclonal Antibody – Cat# MBS4750128

Immunohistochemistry (IHC) of anti-STAT6 antibody

Immunohistochemical analysis of paraffin-embedded rat liver, using STAT6 Antibody.
Rabbit Anti-STAT6 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS4750128

Immunofluorescence (IF) of anti-STAT6 antibody

Immunofluorescent analysis of Hela cells, using STAT6 Antibody.
Rabbit Anti-STAT6 Polyclonal Antibody, Immunofluorescence (IF) – Cat# MBS4750128

Other Notes

Small volumes of anti-STAT6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for STAT6 purchase

MBS4750128 is an antibody targeting STAT6. Also known as Anti-STAT6 Rabbit pAb. Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for STAT6. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
signal transducer and activator of transcription 6 isoform 1
NCBI Official Synonym Full Names
signal transducer and activator of transcription 6
NCBI Official Symbol
STAT6
NCBI Official Synonym Symbols
STAT6B; STAT6C; D12S1644; IL-4-STAT
UniProt Protein Name
Signal transducer and activator of transcription 6
UniProt Synonym Protein Names
IL-4 Stat
UniProt Gene Name
STAT6
NCBI Protein Information
signal transducer and activator of transcription 6

NCBI Summary for STAT6

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
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UniProt Comments for STAT6

Carries out a dual function: signal transduction and activation of transcription. Involved in IL4/interleukin-4- and IL3/interleukin-3-mediated signaling.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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