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SYT7 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9202401

Synaptotagmins, such as SYT7, are brain-specificcalcium-dependent phospholipid-binding proteins that play a role insynaptic exocytosis and neurotransmitter release. See MIM600782. More details

$240 / 0.08 mL +1 FREE 8GB USB
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
SYT7, Polyclonal Antibody
Full Product Name
SYT7 Antibody (N-term)
Product Gene Name
Product Synonym Names
Synaptotagmin-7; IPCA-7; Prostate cancer-associated protein 7; Synaptotagmin VII; SytVII; SYT7; PCANAP7
Clonality
Polyclonal
Isotype
Rabbit Ig
Host
Rabbit
Species Reactivity
Human, mouse
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Concentration
Vial Concentration: 0.4 (lot specific)
Specificity
This SYT7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 72-101 amino acids from the N-terminal region of human SYT7.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Antibody/Peptide Pairs
SYT7 peptide (MBS9220691) is used for blocking the activity of SYT7 antibody (MBS9202401)
Molecular Weight
45501
Immunogen Sequence Positions
72-101
OMIM
604146
3D Structure
ModBase 3D Structure for O43581
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Applications Tested/Suitable for anti-SYT7 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-SYT7 antibody
WB~~1:1000

Western Blot (WB) of anti-SYT7 antibody

SYT7 Antibody (N-term) western blot analysis in human uterine tomer tissue lysates (35ug/lane).This demonstrates the SYT7 antibody detected the SYT7 protein (arrow).
Rabbit Anti-SYT7 Polyclonal Antibody – Cat# MBS9202401

Western Blot (WB) of anti-SYT7 antibody

SYT7 Antibody (N-term) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the SYT7 antibody detected the SYT7 protein (arrow).
Rabbit Anti-SYT7 Polyclonal Antibody, Western Blot (WB) – Cat# MBS9202401

Product References and Citations for anti-SYT7 antibody

Bailey, S.D., et al. Diabetes Care (2010) In press :
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Fukuda, M., et al. Biochem. J. 365 (PT 1), 173-180 (2002) :
Caler, E.V., et al. J. Exp. Med. 193(9):1097-1104(2001)
Mizutani, A., et al. J. Biol. Chem. 275(13):9823-9831(2000)

Other Notes

Small volumes of anti-SYT7 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SYT7 purchase

MBS9202401 is an antibody targeting SYT7. Also known as SYT7 Antibody (N-term). Reactive in Human, mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for SYT7. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI Related Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
synaptotagmin-7 isoform 1
NCBI Official Synonym Full Names
synaptotagmin VII
NCBI Official Symbol
SYT7
NCBI Official Synonym Symbols
IPCA7; IPCA-7; SYTVII; PCANAP7; SYT-VII
UniProt Protein Name
Synaptotagmin-7
UniProt Synonym Protein Names
IPCA-7; Prostate cancer-associated protein 7; Synaptotagmin VII; SytVII
Protein Family
UniProt Gene Name
SYT7
UniProt Synonym Gene Names
PCANAP7; SytVII
UniProt Entry Name
SYT7_HUMAN
NCBI Protein Information
synaptotagmin-7

NCBI Summary for SYT7

This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. A similar protein in rodents mediates hormone secretion and lysosome exocytosis. In humans, expression of this gene has been associated with prostate cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]
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UniProt Comments for SYT7

SYT7: May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Belongs to the synaptotagmin family.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 11q12.2

Cellular Component: synaptic vesicle membrane; lysosome; plasma membrane; integral to membrane; cell junction

Molecular Function: calcium-dependent phospholipid binding; transporter activity; calcium ion binding

Biological Process: positive regulation of calcium ion-dependent exocytosis; exocytosis; plasma membrane repair; regulation of insulin secretion
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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